"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
| Descriptor ID |
D020121
|
| MeSH Number(s) |
D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
|
| Concept/Terms |
5' Untranslated Regions- 5' Untranslated Regions
- 5' Untranslated Region
- Region, 5' Untranslated
- Regions, 5' Untranslated
- Untranslated Region, 5'
- Untranslated Regions, 5'
- 5'UTR
- 5'UTRs
- Leader Sequences, mRNA
- Leader Sequence, mRNA
- Sequence, mRNA Leader
- Sequences, mRNA Leader
- mRNA Leader Sequence
- mRNA Leader Sequences
- 5' UTR
- 5' UTRs
- UTR, 5'
- UTRs, 5'
- Leader mRNA Sequences
- Leader mRNA Sequence
- Sequence, Leader mRNA
- Sequences, Leader mRNA
- mRNA Sequence, Leader
- mRNA Sequences, Leader
|
Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".
This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 4 | 4 |
| 2003 | 0 | 5 | 5 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 4 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.
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Flagellar switch inverted repeats impact heterogeneity in flagellar gene expression and thus C. difficile RT027/MLST1 virulence. Cell Rep. 2025 Jun 24; 44(6):115830.
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Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5' untranslated region. Nat Commun. 2025 Jan 08; 16(1):483.
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Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease. Nat Commun. 2024 Jul 09; 15(1):5748.
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Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers. Int J Mol Sci. 2022 Sep 12; 23(18).
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Beyond Trinucleotide Repeat Expansion in Fragile X Syndrome: Rare Coding and Noncoding Variants in FMR1 and Associated Phenotypes. Genes (Basel). 2021 10 22; 12(11).
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YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
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Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions. Nucleic Acids Res. 2020 09 25; 48(17):9521-9537.
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Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nat Med. 2019 02; 25(2):301-311.
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The 5'UTR variant of ERCC5 fails to influence outcomes in ovarian and lung cancer patients undergoing treatment with platinum-based drugs. Sci Rep. 2016 12 14; 6:39217.
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The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6.