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Dorothy A. Sipkins

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ridge SM, Whiteley AE, Yao H, Price TT, Brockman ML, Murray AS, Simon BG, Islam P, Sipkins DA. Pan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse. Leuk Lymphoma. 2021 11; 62(11):2690-2702. PMID: 34355654.
      View in: PubMed
    2. Whiteley AE, Price TT, Cantelli G, Sipkins DA. Leukaemia: a model metastatic disease. Nat Rev Cancer. 2021 07; 21(7):461-475. PMID: 33953370.
      View in: PubMed
    3. Srinivasan ES, Tan AC, Anders CK, Pendergast AM, Sipkins DA, Ashley DM, Fecci PE, Khasraw M. Salting the Soil: Targeting the Microenvironment of Brain Metastases. Mol Cancer Ther. 2021 03; 20(3):455-466. PMID: 33402399.
      View in: PubMed
    4. Fan S, Price T, Huang W, Plue M, Warren J, Sundaramoorthy P, Paul B, Feinberg D, MacIver N, Chao N, Sipkins D, Kang Y. PINK1-Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B-Mediated Hippo-YAP/TAZ Pathway. Adv Sci (Weinh). 2020 Mar; 7(5):1900860. PMID: 32154065.
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    5. Yao H, Price TT, Cantelli G, Ngo B, Warner MJ, Olivere L, Ridge SM, Jablonski EM, Therrien J, Tannheimer S, McCall CM, Chenn A, Sipkins DA. Leukaemia hijacks a neural mechanism to invade the central nervous system. Nature. 2018 08; 560(7716):55-60. PMID: 30022166.
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    6. Rein LA, Wisler JW, Kim J, Theriot B, Huang L, Price T, Yang H, Chen M, Chen W, Sipkins D, Fedoriw Y, Walker JK, Premont RT, Lefkowitz RJ. ß-Arrestin2 mediates progression of murine primary myelofibrosis. JCI Insight. 2017 12 21; 2(24). PMID: 29263312.
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    7. Price TT, Sipkins DA. E-Selectin and SDF-1 regulate metastatic trafficking of breast cancer cells within the bone. Mol Cell Oncol. 2017; 4(4):e1214771. PMID: 28868340.
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    8. Price TT, Burness ML, Sivan A, Warner MJ, Cheng R, Lee CH, Olivere L, Comatas K, Magnani J, Kim Lyerly H, Cheng Q, McCall CM, Sipkins DA. Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone. Sci Transl Med. 2016 05 25; 8(340):340ra73. PMID: 27225183.
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    9. Price T, Sipkins DA. Rewiring the niche: sympathetic neuropathy drives malignant niche transformation. Cell Stem Cell. 2014 Sep 04; 15(3):261-262. PMID: 25192459.
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    10. Locke F, Agarwal R, Kunnavakkam R, van Besien K, Larson RA, Odenike O, Godley LA, Liu H, Le Beau MM, Gurbuxani S, Thirman MJ, Sipkins D, White C, Artz A, Stock W. A novel clofarabine bridge strategy facilitates allogeneic transplantation in patients with relapsed/refractory leukemia and high-risk myelodysplastic syndromes. Bone Marrow Transplant. 2013 Nov; 48(11):1437-43. PMID: 23771005.
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    11. Boyerinas B, Zafrir M, Yesilkanal AE, Price TT, Hyjek EM, Sipkins DA. Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy. Blood. 2013 Jun 13; 121(24):4821-31. PMID: 23589674.
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    12. Fox MF, Pontier A, Gurbuxani S, Sipkins DA. Stem cell factor expression in B cell malignancies is influenced by the niche. Leuk Lymphoma. 2013 Oct; 54(10):2274-80. PMID: 23418895.
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    13. Larson SM, Campbell NP, Huo D, Artz A, Zhang Y, Gajria D, Green M, Weiner H, Daugherty C, Odenike O, Godley LA, Hyjek E, Gurbuxani S, Thirman M, Sipkins D, Van Besien K, Larson RA, Stock W. High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML). Leuk Lymphoma. 2012 Mar; 53(3):445-50. PMID: 21913806.
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    14. Boyerinas B, Sipkins DA. HSPCs in the balance: The vascular niche. Cell Stem Cell. 2010 Dec 03; 7(6):645-6. PMID: 21112557.
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    15. Burness ML, Sipkins DA. The stem cell niche in health and malignancy. Semin Cancer Biol. 2010 Apr; 20(2):107-15. PMID: 20510363.
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    16. Sipkins DA. Rendering the leukemia cell susceptible to attack. N Engl J Med. 2009 Sep 24; 361(13):1307-9. PMID: 19776414.
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    17. Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008 Dec 19; 322(5909):1861-5. PMID: 19095944.
      View in: PubMed
    18. Sipkins DA. Chemotherapy and the bone marrow stroma. Leuk Lymphoma. 2008 Jan; 49(1):17-8. PMID: 18203006.
      View in: PubMed
    19. Colmone A, Sipkins DA. Beyond angiogenesis: the role of endothelium in the bone marrow vascular niche. Transl Res. 2008 Jan; 151(1):1-9. PMID: 18061122.
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    20. Wei X, Sipkins DA, Pitsillides CM, Novak J, Georgakoudi I, Lin CP. Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging. 2005 Oct-Dec; 4(4):415-6. PMID: 16285902.
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    21. Sipkins DA, Wei X, Wu JW, Runnels JM, Côté D, Means TK, Luster AD, Scadden DT, Lin CP. In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. Nature. 2005 Jun 16; 435(7044):969-73. PMID: 15959517.
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    22. Sipkins DA, Gijbels K, Tropper FD, Bednarski M, Li KC, Steinman L. ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging. J Neuroimmunol. 2000 Apr 03; 104(1):1-9. PMID: 10683508.
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    23. Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nat Med. 1998 May; 4(5):623-6. PMID: 9585240.
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    24. Storrs RW, Tropper FD, Li HY, Song CK, Sipkins DA, Kuniyoshi JK, Bednarski MD, Strauss HW, Li KC. Paramagnetic polymerized liposomes as new recirculating MR contrast agents. J Magn Reson Imaging. 1995 Nov-Dec; 5(6):719-24. PMID: 8748492.
      View in: PubMed
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