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Rex C. Haydon

TitleProfessor
InstitutionUniversity of Chicago
DepartmentOrthopaedic Surg & Rehab Med
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Rex Haydon, MD, PhD, focuses on the comprehensive treatment of malignant and benign tumors in bone or soft tissue. He specializes in the surgical care of bone and soft tissue tumors, including limb-salvage and reconstructive surgery of the upper and lower extremities. Dr. Haydon works with an integrated team of specialists to ensure that patients have access to the most innovative and effective treatment options available.

    Also a skilled physician scientist, his research focuses on advancing the treatment of musculoskeletal tumors. Dr. Haydon has a particular interest in the underlying causes of musculoskeletal neoplasms. Author of more than 25 articles and book chapters, he has accepted career development awards from both the Orthopaedic Research and Education Foundation and the National Institutes of Health. Additionally, Dr. Haydon's research has been supported by the Musculoskeletal Tumor Foundation.


    Collapse Biography 
    Collapse education and training
    The University of Chicago, Chicago, Illinois B.A.1988Anthropology
    The University of Chicago, Chicago, Illinois M.A.1993 MAPSS (Social Sciences),
    The University of Chicago, Chicago, Illinois Ph.D1996Anthropology
    The University of Chicago, Chicago, IllinoisResident2001Orthopaedic Surgery
    The University of Chicago, Chicago, IllinoisOrthopaedic Fellowship2002Research
    The University of Chicago, Chicago, Illinois Orthopaedic Fellowship 2003Oncology
    Collapse awards and honors
    2018Orlov Visiting Professor in Orthopaedic Oncology, Loyola University of Chicago
    2017Senior Faculty Scholar, Bucksbaum Institute for Clinical Excellence
    2011Gerald S. Laros Resident Teaching Award
    2010Keynote Speaker, Pritzker School of Medicine White Coat Ceremony
    2009American-British-Canadian Traveling Fellowship, AOA
    2008Induction into ??? (Beta Chapter) as Faculty member by Pritzker School of Medicine
    2007Gerald S. Laros Resident Teaching Award
    2006Orthopaedic Research Society Career Development Award
    2006Kappa Delta Ann Doner Vaughan Award, Co-Recipient, AAOS/ORS
    2006Marshall R. Urist Young Investigator Award, Association of Bone & Joint Surgeons
    2005John J. Fahey, MD Memorial North American Traveling Fellowship, AOA
    2004 - 2009K08 Mentored Clinical Scientist Development Award, NIH-NIAMS
    2003 - 2005Thomas M. Coffman OREF Career Development Award
    2002Best Poster Award: Charles Huggins Conference: “Upregulation Of cKit In Giant Cell Tumor of Bone: Po
    2000Howard Schneider Award for Best Manuscript at the OREF Midwest Conference

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wang X, Yuan C, Huang B, Fan J, Feng Y, Li AJ, Zhang B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Wu D, Chen X, Liu B, Wagstaff W, He F, Wu X, Luo H, Zhang J, Zhang M, Haydon RC, Luu HH, Lee MJ, Moriatis Wolf J, Huang A, He TC, Zeng Z. Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells. ACS Synth Biol. 2019 Sep 20; 8(9):2092-2105. PMID: 31465214.
      View in: PubMed
    2. Fan J, Feng Y, Zhang R, Zhang W, Shu Y, Zeng Z, Huang S, Zhang L, Huang B, Wu D, Zhang B, Wang X, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Liu B, Wagstaff W, He F, Wu X, Zhang J, Moriatis Wolf J, Lee MJ, Haydon RC, Luu HH, Huang A, He TC, Yan S. A simplified system for the effective expression and delivery of functional mature microRNAs in mammalian cells. Cancer Gene Ther. 2019 Jun 20. PMID: 31222181.
      View in: PubMed
    3. Wang X, Wu X, Zhang Z, Ma C, Wu T, Tang S, Zeng Z, Huang S, Gong C, Yuan C, Zhang L, Feng Y, Huang B, Liu W, Zhang B, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Haydon RC, Luu HH, Peng B, Liu X, He TC. Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914. PMID: 30559409.
      View in: PubMed
    4. Shu Y, Yang C, Ji X, Zhang L, Bi Y, Yang K, Gong M, Liu X, Guo Q, Su Y, Qu X, Nan G, Zhao C, Zeng Z, Yu X, Zhang R, Yan S, Lei J, Wu K, Wu Y, An L, Huang S, Gong C, Yuan C, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Haydon RC, Luu HH, Reid RR, Wolf JM, Lee MJ, He TC, Li Y. Reversibly immortalized human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are responsive to BMP9-induced osteogenic and adipogenic differentiation. J Cell Biochem. 2018 11; 119(11):8872-8886. PMID: 30076626.
      View in: PubMed
    5. Yu X, Xia Y, Zeng L, Zhang X, Chen L, Yan S, Zhang R, Zhao C, Zeng Z, Shu Y, Huang S, Lei J, Yuan C, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Luo W, Wang X, Zhang H, Haydon RC, Luu HH, He TC, Gan H. A blockade of PI3K? signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Sci Rep. 2018 Jul 20; 8(1):10988. PMID: 30030497.
      View in: PubMed
    6. Yu X, Liu F, Zeng L, He F, Zhang R, Yan S, Zeng Z, Shu Y, Zhao C, Wu X, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Huang S, Ji X, Gong C, Yuan C, Zhang L, Feng Y, Huang B, Liu W, Zhang B, Dai Z, Wang X, Liu B, Haydon RC, Luu HH, Gan H, He TC, Chen L. Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells. Cell Physiol Biochem. 2018; 47(3):957-971. PMID: 29843133.
      View in: PubMed
    7. Feng Y, Spezia M, Huang S, Yuan C, Zeng Z, Zhang L, Ji X, Liu W, Huang B, Luo W, Liu B, Lei Y, Du S, Vuppalapati A, Luu HH, Haydon RC, He TC, Ren G. Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes Dis. 2018 Jun; 5(2):77-106. PMID: 30258937.
      View in: PubMed
    8. Yan S, Zhang R, Wu K, Cui J, Huang S, Ji X, An L, Yuan C, Gong C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Liu B, Haydon RC, Lee MJ, Reid RR, Wolf JM, Shi Q, Luu HH, He TC, Weng Y. Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference. Genes Dis. 2018 Jun; 5(2):172-184. PMID: 30258947.
      View in: PubMed
    9. Yu X, Chen L, Wu K, Yan S, Zhang R, Zhao C, Zeng Z, Shu Y, Huang S, Lei J, Ji X, Yuan C, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Luo W, Wang X, Liu B, Haydon RC, Luu HH, He TC, Gan H. Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs). Genes Dis. 2018 Jun; 5(2):137-149. PMID: 30258943.
      View in: PubMed
    10. Zeng Z, Huang B, Huang S, Zhang R, Yan S, Yu X, Shu Y, Zhao C, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Ji X, Gong C, Yuan C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Haydon RC, Luu HH, Zhou L, Reid RR, He TC, Wu X. The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis. 2018 Mar; 5(1):62-74. PMID: 30159383.
      View in: PubMed
    11. Hu X, Li L, Yu X, Zhang R, Yan S, Zeng Z, Shu Y, Zhao C, Wu X, Lei J, Li Y, Zhang W, Yang C, Wu K, Wu Y, An L, Huang S, Ji X, Gong C, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Haydon RC, Luu HH, Reid RR, Lee MJ, Wolf JM, Yu Z, He TC. CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs). Oncotarget. 2017 Dec 19; 8(67):111847-111865. PMID: 29340096.
      View in: PubMed
    12. Liao J, Yu X, Hu X, Fan J, Wang J, Zhang Z, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Li Y, Zhang W, Cui J, Ma C, Li L, Yu Y, Wu T, Wu X, Lei J, Wang J, Yang C, Wu K, Wu Y, Tang J, He BC, Deng ZL, Luu HH, Haydon RC, Reid RR, Lee MJ, Wolf JM, Huang W, He TC. lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Aug 08; 8(32):53581-53601. PMID: 28881833.
      View in: PubMed
    13. Liao J, Yu X, Hu X, Fan J, Wang J, Zhang Z, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Li Y, Zhang W, Cui J, Ma C, Li L, Yu Y, Wu T, Wu X, Lei J, Wang J, Yang C, Wu K, Wu Y, Tang J, He BC, Deng ZL, Luu HH, Haydon RC, Reid RR, Lee MJ, Wolf JM, Huang W, He TC. lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Jun 27. PMID: 28668938.
      View in: PubMed
    14. Bawa HS, Moore DD, Pelayo JC, Cipriani N, Mak G, Haydon RC. Pediatric Chondrosarcoma of the Sternum Resected with Thorascopic Assistance. Open Orthop J. 2017; 11:479-485. PMID: 28694886.
      View in: PubMed
    15. Fan J, Wei Q, Liao J, Zou Y, Song D, Xiong D, Ma C, Hu X, Qu X, Chen L, Li L, Yu Y, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Zhang W, Haydon RC, Luu HH, Huang A, He TC, Tang H. Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors. Oncotarget. 2017 Apr 18; 8(16):27105-27119. PMID: 28404920.
      View in: PubMed
    16. Zhang F, Li Y, Zhang H, Huang E, Gao L, Luo W, Wei Q, Fan J, Song D, Liao J, Zou Y, Liu F, Liu J, Huang J, Guo D, Ma C, Hu X, Li L, Qu X, Chen L, Yu X, Zhang Z, Wu T, Luu HH, Haydon RC, Song J, He TC, Ji P. Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC). Oncotarget. 2017 Feb 21; 8(8):12968-12982. PMID: 28099902.
      View in: PubMed
    17. Aneja A, Jiang JJ, Cohen-Rosenblum A, Luu HL, Peabody TD, Attar S, Luo TD, Haydon RC. Thromboembolic Disease in Patients with Metastatic Femoral Lesions: A Comparison Between Prophylactic Fixation and Fracture Fixation. J Bone Joint Surg Am. 2017 Feb 15; 99(4):315-323. PMID: 28196033.
      View in: PubMed
    18. Choy B, Hyjek E, Montag AG, Pytel P, Haydon R, Luu HH, Zhen CJ, Long BC, Kadri S, Segal JP, Furtado LV, Cipriani NA. High prevalence of MiTF staining in undifferentiated pleomorphic sarcoma: caution in the use of melanocytic markers in sarcoma. Histopathology. 2017 Apr; 70(5):734-745. PMID: 27926791.
      View in: PubMed
    19. Deng Y, Wang Z, Zhang F, Qiao M, Yan Z, Wei Q, Wang J, Liu H, Fan J, Zou Y, Liao J, Hu X, Chen L, Yu X, Haydon RC, Luu HH, Qi H, He TC, Zhang J. A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88. PMID: 27497986.
      View in: PubMed
    20. Wei Q, Liao J, Yu X, Wang EJ, Wang C, Luu HH, Haydon RC, Lee MJ, He TC. An NgAgo tool for genome editing: did CRISPR/Cas9 just find a competitor? Genes Dis. 2016 Sep; 3(3):169-170. PMID: 28066798.
      View in: PubMed
    21. Ye J, Wang J, Zhu Y, Wei Q, Wang X, Yang J, Tang S, Liu H, Fan J, Zhang F, Farina EM, Mohammed MK, Zou Y, Song D, Liao J, Huang J, Guo D, Lu M, Liu F, Liu J, Li L, Ma C, Hu X, Haydon RC, Lee MJ, Reid RR, Ameer GA, Yang L, He TC. A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells. Biomed Mater. 2016 Apr 21; 11(2):025021. PMID: 27097687.
      View in: PubMed
    22. Denduluri SK, Scott B, Lamplot JD, Yin L, Yan Z, Wang Z, Ye J, Wang J, Wei Q, Mohammed MK, Haydon RC, Kang RW, He TC, Athiviraham A, Ho SH, Shi LL. Immortalized Mouse Achilles Tenocytes Demonstrate Long-Term Proliferative Capacity While Retaining Tenogenic Properties. Tissue Eng Part C Methods. 2016 Mar; 22(3):280-9. PMID: 26959762.
      View in: PubMed
    23. Wang J, Wei Q, Wang X, Tang S, Liu H, Zhang F, Mohammed MK, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Hu X, Haydon RC, He TC, Luu HH. Transition to resistance: An unexpected role of the EMT in cancer chemoresistance. Genes Dis. 2016 Mar; 3(1):3-6. PMID: 28491932.
      View in: PubMed
    24. Li Y, Wagner ER, Yan Z, Wang Z, Luther G, Jiang W, Ye J, Wei Q, Wang J, Zhao L, Lu S, Wang X, Mohammed MK, Tang S, Liu H, Fan J, Zhang F, Zou Y, Song D, Liao J, Haydon RC, Luu HH, He TC. The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation. Cell Physiol Biochem. 2015; 37(6):2375-92. PMID: 26646427.
      View in: PubMed
    25. Deng Y, Zhang J, Wang Z, Yan Z, Qiao M, Ye J, Wei Q, Wang J, Wang X, Zhao L, Lu S, Tang S, Mohammed MK, Liu H, Fan J, Zhang F, Zou Y, Liao J, Qi H, Haydon RC, Luu HH, He TC, Tang L. Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523. PMID: 26639992.
      View in: PubMed
    26. Yang K, Wang X, Zhang H, Wang Z, Nan G, Li Y, Zhang F, Mohammed MK, Haydon RC, Luu HH, Bi Y, He TC. The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest. 2016 Feb; 96(2):116-36. PMID: 26618721.
      View in: PubMed
    27. Green JD, Tollemar V, Dougherty M, Yan Z, Yin L, Ye J, Collier Z, Mohammed MK, Haydon RC, Luu HH, Kang R, Lee MJ, Ho SH, He TC, Shi LL, Athiviraham A. Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering. Genes Dis. 2015 Dec; 2(4):307-327. PMID: 26835506.
      View in: PubMed
    28. Shao C, Shen C, Lu E, Haydon RC, Luu HH, Athiviraham A, He TC, Lee MJ. Damage control: Harnessing prostaglandin E2 as a potential healing factor of tissue injuries. Genes Dis. 2015 Dec; 2(4):295-298. PMID: 26819965.
      View in: PubMed
    29. Mohammed MK, Shao C, Luu HH, Haydon RC. Opening the LOX to bone metastasis: The role of secreted lysyl oxidase in skeletal recurrence of breast cancers. Genes Dis. 2015 Dec; 2(4):288-290. PMID: 28529966.
      View in: PubMed
    30. Denduluri SK, Wang Z, Yan Z, Wang J, Wei Q, Mohammed MK, Haydon RC, Luu HH, He TC. Molecular pathogenesis and therapeutic strategies of human osteosarcoma. J Biomed Res. 2015 Aug 30; 30. PMID: 26496981.
      View in: PubMed
    31. Zhang Q, Wang J, Deng F, Yan Z, Xia Y, Wang Z, Ye J, Deng Y, Zhang Z, Qiao M, Li R, Denduluri SK, Wei Q, Zhao L, Lu S, Wang X, Tang S, Liu H, Luu HH, Haydon RC, He TC, Jiang L. TqPCR: A Touchdown qPCR Assay with Significantly Improved Detection Sensitivity and Amplification Efficiency of SYBR Green qPCR. PLoS One. 2015; 10(7):e0132666. PMID: 26172450.
      View in: PubMed
    32. Wang J, Wei Q, Ye J, Denduluri SK, Wang X, Mohammed MK, Luu HH, Haydon RC, He TC. Insider information: Testing cancer drug sensitivity for personalized therapy. Genes Dis. 2015 Sep; 2(3):219-221. PMID: 26491709.
      View in: PubMed
    33. Chen X, Cui J, Yan Z, Zhang H, Chen X, Wang N, Shah P, Deng F, Zhao C, Geng N, Li M, Denduluri SK, Haydon RC, Luu HH, Reid RR, He TC. Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system. Genes Dis. 2015 Mar; 2(1):96-105. PMID: 25815368.
      View in: PubMed
    34. Liao Z, Nan G, Yan Z, Zeng L, Deng Y, Ye J, Zhang Z, Qiao M, Li R, Denduluri S, Wang J, Wei Q, Geng N, Zhao L, Lu S, Wang X, Zhou G, Luu HH, Haydon RC, He TC, Wang Z. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets. 2015; 15(8):726-38. PMID: 26118906.
      View in: PubMed
    35. Jo A, Denduluri S, Zhang B, Wang Z, Yin L, Yan Z, Kang R, Shi LL, Mok J, Lee MJ, Haydon RC. The versatile functions of Sox9 in development, stem cells, and human diseases. Genes Dis. 2014 Dec; 1(2):149-161. PMID: 25685828.
      View in: PubMed
    36. Zhang H, Wang J, Deng F, Huang E, Yan Z, Wang Z, Deng Y, Zhang Q, Zhang Z, Ye J, Qiao M, Li R, Wang J, Wei Q, Zhou G, Luu HH, Haydon RC, He TC, Deng F. Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 Jan; 39:145-54. PMID: 25468367.
      View in: PubMed
    37. Deng F, Chen X, Liao Z, Yan Z, Wang Z, Deng Y, Zhang Q, Zhang Z, Ye J, Qiao M, Li R, Denduluri S, Wang J, Wei Q, Li M, Geng N, Zhao L, Zhou G, Zhang P, Luu HH, Haydon RC, Reid RR, Yang T, He TC. A simplified and versatile system for the simultaneous expression of multiple siRNAs in mammalian cells using Gibson DNA Assembly. PLoS One. 2014; 9(11):e113064. PMID: 25398142.
      View in: PubMed
    38. Bi Y, He Y, Huang J, Su Y, Zhu GH, Wang Y, Qiao M, Zhang BQ, Zhang H, Wang Z, Liu W, Cui J, Kang Q, Zhang Z, Deng Y, Li R, Zhang Q, Yang K, Luu HH, Haydon RC, He TC, Tang N. Functional characteristics of reversibly immortalized hepatic progenitor cells derived from mouse embryonic liver. Cell Physiol Biochem. 2014; 34(4):1318-38. PMID: 25301359.
      View in: PubMed
    39. Wang RN, Green J, Wang Z, Deng Y, Qiao M, Peabody M, Zhang Q, Ye J, Yan Z, Denduluri S, Idowu O, Li M, Shen C, Hu A, Haydon RC, Kang R, Mok J, Lee MJ, Luu HL, Shi LL. Bone Morphogenetic Protein (BMP) signaling in development and human diseases. Genes Dis. 2014 Sep; 1(1):87-105. PMID: 25401122.
      View in: PubMed
    40. Zhang Y, Chen X, Qiao M, Zhang BQ, Wang N, Zhang Z, Liao Z, Zeng L, Deng Y, Deng F, Zhang J, Yin L, Liu W, Zhang Q, Ya Z, Ye J, Wang Z, Zhou L, Luu HH, Haydon RC, He TC, Zhang H. Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. Oncol Rep. 2014 Sep; 32(3):1013-20. PMID: 24993644.
      View in: PubMed
    41. Wang N, Zhang W, Cui J, Zhang H, Chen X, Li R, Wu N, Chen X, Wen S, Zhang J, Yin L, Deng F, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Ye J, Deng Y, Wang Z, Qiao M, Luu HH, Haydon RC, Shi LL, Liang H, He TC. The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs). PLoS One. 2014; 9(5):e97316. PMID: 24845466.
      View in: PubMed
    42. Lamplot JD, Liu B, Yin L, Zhang W, Wang Z, Luther G, Wagner E, Li R, Nan G, Shui W, Yan Z, Rames R, Deng F, Zhang H, Liao Z, Liu W, Zhang J, Zhang Z, Zhang Q, Ye J, Deng Y, Qiao M, Haydon RC, Luu HH, Angeles J, Shi LL, He TC, Ho SH. Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype. Cell Transplant. 2015; 24(6):1053-66. PMID: 24800751.
      View in: PubMed
    43. Wu N, Zhang H, Deng F, Li R, Zhang W, Chen X, Wen S, Wang N, Zhang J, Yin L, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Wu D, Ye J, Deng Y, Yang K, Luu HH, Haydon RC, He TC. Overexpression of Ad5 precursor terminal protein accelerates recombinant adenovirus packaging and amplification in HEK-293 packaging cells. Gene Ther. 2014 Jul; 21(7):629-37. PMID: 24784448.
      View in: PubMed
    44. Wen S, Zhang H, Li Y, Wang N, Zhang W, Yang K, Wu N, Chen X, Deng F, Liao Z, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Zhou G, Luu HH, Haydon RC, Shi LL, He TC, Wei G. Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs). PLoS One. 2014; 9(4):e94397. PMID: 24714676.
      View in: PubMed
    45. Wang N, Zhang H, Zhang BQ, Liu W, Zhang Z, Qiao M, Zhang H, Deng F, Wu N, Chen X, Wen S, Zhang J, Liao Z, Zhang Q, Yan Z, Yin L, Ye J, Deng Y, Luu HH, Haydon RC, Liang H, He TC. Adenovirus-mediated efficient gene transfer into cultured three-dimensional organoids. PLoS One. 2014; 9(4):e93608. PMID: 24695466.
      View in: PubMed
    46. Zhao C, Wu N, Deng F, Zhang H, Wang N, Zhang W, Chen X, Wen S, Zhang J, Yin L, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Wu D, Ye J, Deng Y, Zhou G, Luu HH, Haydon RC, Si W, He TC. Adenovirus-mediated gene transfer in mesenchymal stem cells can be significantly enhanced by the cationic polymer polybrene. PLoS One. 2014; 9(3):e92908. PMID: 24658746.
      View in: PubMed
    47. Wang J, Zhang H, Zhang W, Huang E, Wang N, Wu N, Wen S, Chen X, Liao Z, Deng F, Yin L, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng F. Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev. 2014 Jun 15; 23(12):1405-16. PMID: 24517722.
      View in: PubMed
    48. Li R, Zhang W, Cui J, Shui W, Yin L, Wang Y, Zhang H, Wang N, Wu N, Nan G, Chen X, Wen S, Deng F, Zhang H, Zhou G, Liao Z, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng ZL. Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets. 2014; 14(3):274-85. PMID: 24605944.
      View in: PubMed
    49. Moore DD, Haydon RC. Ewing's sarcoma of bone. Cancer Treat Res. 2014; 162:93-115. PMID: 25070232.
      View in: PubMed
    50. Gao Y, Huang E, Zhang H, Wang J, Wu N, Chen X, Wang N, Wen S, Nan G, Deng F, Liao Z, Wu D, Zhang B, Zhang J, Haydon RC, Luu HH, Shi LL, He TC. Crosstalk between Wnt/ß-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2013; 8(12):e82436. PMID: 24340027.
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    51. Zhang W, Zhang H, Wang N, Zhao C, Zhang H, Deng F, Wu N, He Y, Chen X, Zhang J, Wen S, Liao Z, Zhang Q, Zhang Z, Liu W, Yan Z, Luu HH, Haydon RC, Zhou L, He TC. Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98. PMID: 24324366.
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    52. Kong Y, Zhang H, Chen X, Zhang W, Zhao C, Wang N, Wu N, He Y, Nan G, Zhang H, Wen S, Deng F, Liao Z, Wu D, Zhang J, Qin X, Haydon RC, Luu HH, He TC, Zhou L. Destabilization of heterologous proteins mediated by the GSK3ß phosphorylation domain of the ß-catenin protein. Cell Physiol Biochem. 2013; 32(5):1187-99. PMID: 24335169.
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    53. Chen X, Luther G, Zhang W, Nan G, Wagner ER, Liao Z, Wu N, Zhang H, Wang N, Wen S, He Y, Deng F, Zhang J, Wu D, Zhang B, Haydon RC, Zhou L, Luu HH, He TC. The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cell Physiol Biochem. 2013; 32(4):1083-96. PMID: 24217649.
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    54. Shui W, Zhang W, Yin L, Nan G, Liao Z, Zhang H, Wang N, Wu N, Chen X, Wen S, He Y, Deng F, Zhang J, Luu HH, Shi LL, Hu Z, Haydon RC, Mok JM, He TC. Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. J Biomed Mater Res A. 2014 Oct; 102(10):3429-38. PMID: 24133046.
      View in: PubMed
    55. Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, Zhang H, Li R, Kong Y, Chen X, Shui W, Wang N, Zhao C, Wu N, He Y, Nan G, Chen X, Wen S, Zhang H, Deng F, Wan L, Luu HH, Haydon RC, Shi LL, He TC, Shi Q. Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLoS One. 2013; 8(9):e73086. PMID: 24019898.
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    56. Hu N, Wang C, Liang X, Yin L, Luo X, Liu B, Zhang H, Shui W, Nan G, Wang N, Wu N, Chen X, He Y, Wen S, Deng F, Zhang H, Liao Z, Luu HH, Haydon RC, He TC, Huang W. Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013; 32(2):486-98. PMID: 23988723.
      View in: PubMed
    57. Beederman M, Lamplot JD, Nan G, Wang J, Liu X, Yin L, Li R, Shui W, Zhang H, Kim SH, Zhang W, Zhang J, Kong Y, Denduluri S, Rogers MR, Pratt A, Haydon RC, Luu HH, Angeles J, Shi LL, He TC. BMP signaling in mesenchymal stem cell differentiation and bone formation. J Biomed Sci Eng. 2013 Aug; 6(8A):32-52. PMID: 26819651.
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    128. Haydon RC, Zhou L, Feng T, Breyer B, Cheng H, Jiang W, Ishikawa A, Peabody T, Montag A, Simon MA, He TC. Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma. Clin Cancer Res. 2002 May; 8(5):1288-94. PMID: 12006550.
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    129. Feng T, Li Z, Jiang W, Breyer B, Zhou L, Cheng H, Haydon RC, Ishikawa A, Joudeh MA, He TC. Increased efficiency of cloning large DNA fragments using a lower copy number plasmid. Biotechniques. 2002 May; 32(5):992, 994, 996 passim. PMID: 12019795.
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    130. Haydon RC. Are second-generation antihistamines appropriate for most children and adults? Arch Otolaryngol Head Neck Surg. 2001 Dec; 127(12):1510-3. PMID: 11735828.
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    131. Jiang W, Zhou L, Breyer B, Feng T, Cheng H, Haydon R, Ishikawa A, He TC. Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells. J Biol Chem. 2001 Nov 30; 276(48):45168-74. PMID: 11581265.
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    132. Secor CP, Farrell HA, Haydon RC. Auricular endochondral pseudocysts: diagnosis and management. Plast Reconstr Surg. 1999 Apr; 103(5):1451-7. PMID: 10190442.
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    133. Valentino J, Donnelly MB, Sloan DA, Schwartz RW, Haydon RC. The reliability of six faculty members in identifying important OSCE items. Acad Med. 1998 Feb; 73(2):204-5. PMID: 9484196.
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    134. Haydon R, Donnelly M, Schwartz R, Strodel W, Jones R. Use of standardized patients to identify deficits in student performance and curriculum effectiveness. Am J Surg. 1994 Jul; 168(1):57-64; discussion 64-5. PMID: 8024100.
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    135. Weiss KL, Wax MK, Haydon RC, Kaufman HH, Hurst MK. Intracranial pressure changes during bilateral radical neck dissections. Head Neck. 1993 Nov-Dec; 15(6):546-52. PMID: 8253563.
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    136. Haydon RC. Cutaneous squamous carcinoma and related lesions. Otolaryngol Clin North Am. 1993 Feb; 26(1):57-71. PMID: 8433842.
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    137. Wilson BC, Davidson B, Corey JP, Haydon RC. Comparison of complications following frontal sinus fractures managed with exploration with or without obliteration over 10 years. Laryngoscope. 1988 May; 98(5):516-20. PMID: 3362014.
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    138. Wilson BC, Jarvis BL, Haydon RC. Nontraumatic subluxation of the atlantoaxial joint: Grisel's syndrome. Ann Otol Rhinol Laryngol. 1987 Nov-Dec; 96(6):705-8. PMID: 3688763.
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    139. Liudahl JJ, Haydon RC, Rodman SM. Snoring and related problems: surgical correction. W V Med J. 1986 May; 82(5):127-30. PMID: 3459310.
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