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Xiaochuan Pan

TitleProfessor
InstitutionUniversity of Chicago
DepartmentRadiology-Basic Sciences
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Research of Professor Pan’s lab centers on physics, algorithms, and engineering underpinning tomographic imaging and its biomedical and clinical applications. Dr. Pan and his lab conduct research on advanced theory and algorithms for conventional and spectral computed tomography (CT), positron emission tomography (PET), single-photo-emission computed tomography (SPECT), and tomosynthesis especially digital breast tomosynthesis (DBT) and digital lung tomosynthesis (DLT), supported by grants from federal funding agencies such as NIH and DOD, from state funding agencies, from foundations, and from industry. In collaborating with leading researchers in the field, he and his team have worked on magnetic resonance imaging (MRI) and have also investigated emerging imaging techniques, including electron-paramagnetic resonance imaging (EPRI), phase-contrast CT, and photo-acoustic tomography (PAT), among others. In recent years, he and his team have developed programs that translate theoretical concepts and methods to biomedical application work that includes developing innovative hardware systems and workflows, enabled by advanced algorithms, with a strong emphasis on the relevance and impact of imaging technological solutions tailored to specific applications of biomedical and/or clinical significance. Dr. Pan's lab has established continuous, close clinical and industrial collaboration. Dr. Pan is a Fellow of AAPM, AIMBE, IAMBE, IEEE, OSA, and SPIE.

    Collapse Research 
    Collapse research activities and funding
    R01CA287302     (PAN, XIAOCHUAN)Jul 1, 2024 - Jun 30, 2029
    NIH
    Intraoperative quantitative CT imaging of breast specimen for reducing re-surgery rate and tumor cataloguing
    Role: Principal Investigator
    R21CA263660     (PAN, XIAOCHUAN)Feb 10, 2022 - Jan 31, 2025
    NIH
    Algorithm-Enabled Auto-Calibrating Quantitative Dual-Energy CT
    Role: Principal Investigator
    R01EB026282     (PAN, XIAOCHUAN)Sep 14, 2018 - May 31, 2022
    NIH
    Advanced iterative image reconstruction for digital breast tomosynthesis - Resubmission 01
    Role: Principal Investigator
    R01EB018102     (PAN, XIAOCHUAN)Sep 1, 2014 - Dec 31, 2018
    NIH
    Digital Specimen Tomosynthesis for Volumetric Imaging of Lumpectomy Specimens
    Role: Principal Investigator
    R01CA182264     (PAN, XIAOCHUAN)Jul 1, 2014 - Jun 30, 2018
    NIH
    Development of Advanced C-arm Cone-Beam CT for the Treatment of Liver Cancer
    Role: Principal Investigator
    R13EB018729     (PAN, XIAOCHUAN)Apr 1, 2014 - Mar 31, 2015
    NIH
    36th Annual International Conference of the IEEE Engineering in Medicine and Biol
    Role: Principal Investigator
    R13EB013567     (PAN, XIAOCHUAN)Mar 9, 2011 - Feb 29, 2012
    NIH
    International Symposium on Biomedical Imaging: from Nano to Macro 2011 (ISBI2011)
    Role: Principal Investigator
    R13EB009925     (PAN, XIAOCHUAN)Aug 1, 2009 - Jul 31, 2010
    NIH
    31st Annual International Conference of IEEE Engineeering in Medicine and Biology
    Role: Principal Investigator
    R01CA120540     (PAN, XIAOCHUAN)Jul 27, 2007 - May 31, 2014
    NIH
    Optimized Cone-Beam CT for Image-Guided Radiation Therapy
    Role: Principal Investigator
    R01EB000225     (PAN, XIAOCHUAN)Jul 1, 2000 - Jan 31, 2016
    NIH
    Targeted Imaging in Helical cone-beam CT
    Role: Principal Investigator
    R01CA085593     (PAN, XIAOCHUAN)Jul 1, 2000 - Jun 30, 2005
    NIH
    FOURIER AND SPLINE BASED RECONSTRUCTIONS IN HELICAL CT
    Role: Principal Investigator
    R01EB002765     (PAN, XIAOCHUAN)Apr 1, 1996 - Mar 31, 2007
    NIH
    Non Iterative Methods for 3D SPECT Image Reconstruction
    Role: Principal Investigator
    R01CA070449     (PAN, XIAOCHUAN)Apr 1, 1996 - Mar 31, 2006
    NIH
    Non Iterative Methods for 3D SPECT Image Reconstruction
    Role: Principal Investigator
    R29CA070449     (PAN, XIAOCHUAN)Apr 1, 1996 - Mar 31, 2001
    NIH
    NON-ITERATIVE METHODS FOR 3D SPECT IMAGE RECONSTRUCTION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sidky EY, Wu X, Duan X, Huang H, Zhao W, Zhang LY, Phillips JP, Zhang Z, Chen B, Xia D, Reiser IS, Pan X. A directional total variation minimization algorithm for isotropic resolution in digital breast tomosynthesis. ArXiv. 2024 Jun 11. PMID: 38947918; PMCID: PMC11213119.
      Citations:    
    2. Zhang Z, Epel B, Chen B, Xia D, Sidky EY, Halpern H, Pan X. Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI. J Magn Reson. 2024 Apr; 361:107654. PMID: 38492546.
      Citations: 1     Fields:    
    3. Sidky EY, Barber RF, Kao CM, Pan X, Ren Z. Simultaneous activity and attenuation estimation in TOF-PET with TV-constrained nonconvex optimization. ArXiv. 2024 Feb 09. PMID: 37033460; PMCID: PMC10081343.
      Citations:    
    4. Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Prototyping optimization-based image reconstructions from limited-angular-range data in dual-energy CT. Med Image Anal. 2024 Jan; 91:103025. PMID: 37976869; PMCID: PMC10872817.
      Citations: 1     Fields:    Translation:Humans
    5. Zhang Z, Epel B, Chen B, Xia D, Sidky EY, Qiao Z, Halpern H, Pan X. 4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging. J Magn Reson. 2023 May; 350:107432. PMID: 37058955; PMCID: PMC10197356.
      Citations: 1     Fields:    
    6. Sidky EY, Pan X. Report on the AAPM deep-learning spectral CT Grand Challenge. Med Phys. 2024 Feb; 51(2):772-785. PMID: 36938878; PMCID: PMC10509324.
      Citations: 2     Fields:    Translation:Humans
    7. Chen B, Zhang Z, Xia D, Sidky EY, Gilat-Schmidt T, Pan X. Accurate Image Reconstruction in Dual-Energy CT with Limited-Angular-Range Data Using a Two-Step Method. Bioengineering (Basel). 2022 Dec 06; 9(12). PMID: 36550981; PMCID: PMC9774445.
      Citations: 2     
    8. Sidky EY, Paul ER, Gilat-Schmidt T, Pan X. Spectral calibration of photon-counting detectors at high photon flux. Med Phys. 2022 Oct; 49(10):6368-6383. PMID: 35975670; PMCID: PMC9588681.
      Citations: 4     Fields:    
    9. Sidky EY, Pan X. Report on the AAPM deep-learning sparse-view CT grand challenge. Med Phys. 2022 Aug; 49(8):4935-4943. PMID: 35083750; PMCID: PMC9314462.
      Citations: 2     Fields:    
    10. Zhang Z, Chen B, Xia D, Sidky EY, Pan X. Image reconstruction from data over two orthogonal arcs of limited-angular ranges. Med Phys. 2022 Mar; 49(3):1468-1480. PMID: 35020215; PMCID: PMC10238127.
      Citations: 2     Fields:    
    11. Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Dual-energy CT imaging with limited-angular-range data. Phys Med Biol. 2021 09 17; 66(18). PMID: 34320478; PMCID: PMC8704637.
      Citations: 7     Fields:    
    12. Kulkarni SA, Kulkarni K, Schacht D, Bhole S, Reiser I, Abe H, Bao J, Bethke K, Hansen N, Jaskowiak N, Khan SA, Tseng J, Chen B, Pincus J, Mueller J, Schulte L, LaBomascus B, Zhang Z, Xia D, Pan X, Wietholt C, Modgil D, Lester D, Lan L, Bohara B, Han X. High-Resolution Full-3D Specimen Imaging for Lumpectomy Margin Assessment in Breast Cancer. Ann Surg Oncol. 2021 Oct; 28(10):5513-5524. PMID: 34333705; PMCID: PMC8325528.
      Citations: 7     Fields:    Translation:Humans
    13. Sidky EY, Phillips JP, Zhou W, Ongie G, Cruz-Bastida JP, Reiser IS, Anastasio MA, Pan X. A signal detection model for quantifying overregularization in nonlinear image reconstruction. Med Phys. 2021 Oct; 48(10):6312-6323. PMID: 34169538; PMCID: PMC8697366.
      Citations: 3     Fields:    
    14. Zhang Z, Chen B, Xia D, Sidky EY, Pan X. Directional-TV algorithm for image reconstruction from limited-angular-range data. Med Image Anal. 2021 05; 70:102030. PMID: 33752167; PMCID: PMC8044061.
      Citations: 8     Fields:    Translation:Humans
    15. Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Dual-energy CT imaging over non-overlapping, orthogonal arcs of limited-angular ranges. J Xray Sci Technol. 2021; 29(6):975-985. PMID: 34569984; PMCID: PMC8697364.
      Citations: 3     Fields:    
    16. Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Non-convex primal-dual algorithm for image reconstruction in spectral CT. Comput Med Imaging Graph. 2021 01; 87:101821. PMID: 33373973; PMCID: PMC8050883.
      Citations: 11     Fields:    
    17. Chen B, Liu X, Zhang Z, Xia D, Sidky EY, Pan X. Optimization-based algorithm for solving the discrete x-ray transform with nonlinear partial volume effect. J Med Imaging (Bellingham). 2020 Sep; 7(5):053502. PMID: 33033733; PMCID: PMC7536359.
      Citations: 1     
    18. Davis AM, Pearson EA, Pan X, Pelizzari CA, Al-Hallaq H. Collision-avoiding imaging trajectories for linac mounted cone-beam CT. J Xray Sci Technol. 2019; 27(1):1-16. PMID: 30400125.
      Citations: 3     Fields:    Translation:Humans
    19. Ha W, Sidky EY, Barber RF, Schmidt TG, Pan X. Estimating the spectrum in computed tomography via Kullback-Leibler divergence constrained optimization. Med Phys. 2019 Jan; 46(1):81-92. PMID: 30370544; PMCID: PMC6461446.
      Citations: 9     Fields:    
    20. Xie KX, Xu LT, Zhai YY, Wang ZC, Chen M, Pan XH, Cao SH, Li YQ. The synergistic enhancement of silver nanocubes and graphene oxide on surface plasmon-coupled emission. Talanta. 2019 Apr 01; 195:752-756. PMID: 30625612.
      Citations: 7     Fields:    
    21. Qiao Z, Zhang Z, Pan X, Epel B, Redler G, Xia D, Halpern H. Optimization-based image reconstruction from sparsely sampled data in electron paramagnetic resonance imaging. J Magn Reson. 2018 09; 294:24-34. PMID: 30005191.
      Citations:    Fields:    Translation:Animals
    22. Chen B, Zhang Z, Xia D, Sidky EY, Pan X. Algorithm-enabled partial-angular-scan configurations for dual-energy CT. Med Phys. 2018 May; 45(5):1857-1870. PMID: 29516523; PMCID: PMC5948181.
      Citations: 8     Fields:    
    23. Xia D, Chang YB, Manak J, Siddiqui AH, Zhang Z, Chen B, Sidky EY, Pan X. Reduction of Angularly-Varying-Data Truncation in C-Arm CBCT Imaging. Sens Imaging. 2018 Dec; 19. PMID: 30319317; PMCID: PMC6181237.
      Citations:    
    24. Chen B, Zhang Z, Sidky EY, Xia D, Pan X. Image reconstruction and scan configurations enabled by optimization-based algorithms in multispectral CT. Phys Med Biol. 2017 Nov 02; 62(22):8763-8793. PMID: 29094680; PMCID: PMC5760273.
      Citations: 17     Fields:    Translation:Humans
    25. Rose SD, Sanchez AA, Sidky EY, Pan X. Investigating simulation-based metrics for characterizing linear iterative reconstruction in digital breast tomosynthesis. Med Phys. 2017 Sep; 44(9):e279-e296. PMID: 28901614; PMCID: PMC5604860.
      Citations: 3     Fields:    Translation:Humans
    26. Xia D, Langan DA, Solomon SB, Zhang Z, Chen B, Lai H, Sidky EY, Pan X. Optimization-based image reconstruction with artifact reduction in C-arm CBCT. Phys Med Biol. 2016 10 21; 61(20):7300-7333. PMID: 27694700; PMCID: PMC5109550.
      Citations: 7     Fields:    Translation:HumansAnimals
    27. Zhang Z, Ye J, Chen B, Perkins AE, Rose S, Sidky EY, Kao CM, Xia D, Tung CH, Pan X. Investigation of optimization-based reconstruction with an image-total-variation constraint in PET. Phys Med Biol. 2016 08 21; 61(16):6055-84. PMID: 27452653; PMCID: PMC5062374.
      Citations: 9     Fields:    Translation:Humans
    28. Foygel Barber R, Sidky EY, Gilat Schmidt T, Pan X. An algorithm for constrained one-step inversion of spectral CT data. Phys Med Biol. 2016 05 21; 61(10):3784-818. PMID: 27082489; PMCID: PMC5494281.
      Citations: 38     Fields:    
    29. Zhang Z, Han X, Pearson E, Pelizzari C, Sidky EY, Pan X. Artifact reduction in short-scan CBCT by use of optimization-based reconstruction. Phys Med Biol. 2016 May 07; 61(9):3387-406. PMID: 27046218; PMCID: PMC5496733.
      Citations: 9     Fields:    
    30. Pearson E, Pan X, Pelizzari C. Dynamic intensity-weighted region of interest imaging for conebeam CT. J Xray Sci Technol. 2016 03 17; 24(3):361-77. PMID: 27257875; PMCID: PMC5498113.
      Citations: 2     Fields:    Translation:Humans
    31. Sidky EY, Pan X, Sánchez AA. Use of the Hotelling observer to optimize image reconstruction in digital breast tomosynthesis. J Med Imaging (Bellingham). 2016 Jan; 3(1):011008. PMID: 26702408; PMCID: PMC4686589.
      Citations: 2     
    32. Han X, Pearson E, Pelizzari C, Al-Hallaq H, Sidky EY, Bian J, Pan X. Algorithm-enabled exploration of image-quality potential of cone-beam CT in image-guided radiation therapy. Phys Med Biol. 2015 Jun 21; 60(12):4601-33. PMID: 26020490; PMCID: PMC4610380.
      Citations: 6     Fields:    Translation:Humans
    33. Rose S, Andersen MS, Sidky EY, Pan X. Noise properties of CT images reconstructed by use of constrained total-variation, data-discrepancy minimization. Med Phys. 2015 May; 42(5):2690-8. PMID: 25979067; PMCID: PMC4425727.
      Citations: 7     Fields:    Translation:Humans
    34. Sanchez AA, Sidky EY, Pan X. Region of interest based Hotelling observer for computed tomography with comparison to alternative methods. J Med Imaging (Bellingham). 2014 Dec 08; 1(3):031010. PMID: 25685825; PMCID: PMC4326074.
      Citations: 2     
    35. Sidky EY, Kraemer DN, Roth EG, Reiser IS, Pan X, Ullberg C. Analysis of iterative region-of-interest image reconstruction for x-ray computed tomography. J Med Imaging (Bellingham). 2014 Oct 03; 1(3):031007. PMID: 25685824; PMCID: PMC4326078.
      Citations: 6     
    36. Sanchez AA, Sidky EY, Pan X. Task-based optimization of dedicated breast CT via Hotelling observer metrics. Med Phys. 2014 Oct; 41(10):101917. PMID: 25281969; PMCID: PMC4290542.
      Citations: 15     Fields:    Translation:Humans
    37. Athanassiadis AG, Sidky E, Pelizzari C, Pan X, Jaeger HM, La Rivière PJ. X-ray tomography system to investigate granular materials during mechanical loading. Rev Sci Instrum. 2014 Aug; 85(8):083708. PMID: 25173277.
      Citations: 2     Fields:    
    38. Sidky EY, Chartrand R, Boone JM, Pan X. Constrained TpV Minimization for Enhanced Exploitation of Gradient Sparsity: Application to CT Image Reconstruction. IEEE J Transl Eng Health Med. 2014 Jun 30; 2. PMID: 25401059; PMCID: PMC4228801.
      Citations: 13     Fields:    
    39. Sanchez AA, Sidky EY, Reiser I, Pan X. Comparison of human and Hotelling observer performance for a fan-beam CT signal detection task. Med Phys. 2013 Mar; 40(3):031104. PMID: 23464284; PMCID: PMC3598867.
      Citations: 9     Fields:    Translation:Humans
    40. Sidky EY, Pan X, Jørgensen JS. First-order convex feasibility algorithms for x-ray CT. Med Phys. 2013 Mar; 40(3):031115. PMID: 23464295; PMCID: PMC3598813.
      Citations: 6     Fields:    
    41. Bian J, Wang J, Han X, Sidky EY, Shao L, Pan X. Optimization-based image reconstruction from sparse-view data in offset-detector CBCT. Phys Med Biol. 2013 Jan 21; 58(2):205-30. PMID: 23257068; PMCID: PMC3590115.
      Citations: 16     Fields:    Translation:Humans
    42. Han X, Bian J, Ritman EL, Sidky EY, Pan X. Optimization-based reconstruction of sparse images from few-view projections. Phys Med Biol. 2012 Aug 21; 57(16):5245-73. PMID: 22850194; PMCID: PMC3446871.
      Citations: 28     Fields:    Translation:Humans
    43. Han X, Silver M, Oishi S, Zhang Z, Bian J, Sidky E, Pan X. WE-G-217BCD-06: Fully Incorporated Scanning Geometry for Improved Accuracy in C-Arm CBCT Image Reconstruction. Med Phys. 2012 Jun; 39(6Part28):3973. PMID: 28519635.
      Citations:    Fields:    
    44. Sidky EY, Pan X, Jørgensen JH. Convex optimization problem prototyping for image reconstruction in computed tomography with the Chambolle-Pock algorithm. Phys Med Biol. 2012 May 21; 57(10):3065-91. PMID: 22538474; PMCID: PMC3370658.
      Citations: 63     Fields:    
    45. Sidky EY, Duchin Y, Pan X, Ullberg C. A constrained, total-variation minimization algorithm for low-intensity x-ray CT. Med Phys. 2011 Jul; 38(S1):S117-S125. PMID: 28523707.
      Citations:    
    46. Sidky EY, Duchin Y, Pan X, Ullberg C. A constrained, total-variation minimization algorithm for low-intensity x-ray CT. Med Phys. 2011 Jul; 38 Suppl 1:S117. PMID: 21978112; PMCID: PMC3172126.
      Citations: 20     Fields:    Translation:Animals
    47. Han X, Bian J, Eaker DR, Kline TL, Sidky EY, Ritman EL, Pan X. Algorithm-enabled low-dose micro-CT imaging. IEEE Trans Med Imaging. 2011 Mar; 30(3):606-20. PMID: 20977983; PMCID: PMC3645946.
      Citations: 36     Fields:    Translation:Animals
    48. Bian J, Siewerdsen JH, Han X, Sidky EY, Prince JL, Pelizzari CA, Pan X. Evaluation of sparse-view reconstruction from flat-panel-detector cone-beam CT. Phys Med Biol. 2010 Nov 21; 55(22):6575-99. PMID: 20962368; PMCID: PMC3597413.
      Citations: 100     Fields:    Translation:Humans
    49. Sidky EY, Anastasio MA, Pan X. Image reconstruction exploiting object sparsity in boundary-enhanced X-ray phase-contrast tomography. Opt Express. 2010 May 10; 18(10):10404-22. PMID: 20588896; PMCID: PMC2987648.
      Citations: 13     Fields:    Translation:Cells
    50. Xia D, Cho S, Pan X. Backprojection-filtration reconstruction without invoking a spatially varying weighting factor. Med Phys. 2010 Mar; 37(3):1201-9. PMID: 20384257; PMCID: PMC2837731.
      Citations: 1     Fields:    Translation:Humans
    51. La Riviere P, Vargas P, Xia D, Pan X. Region of interest reconstruction in x-ray fluorescence computed tomography for negligible attenuation. IEEE Trans Nucl Sci. 2010 Feb 01; 57(1):234-241. PMID: 20383286; PMCID: PMC2851101.
      Citations: 2     
    52. Levine MS, Sidky EY, Pan X. Consistency Conditions for Cone-Beam CT Data Acquired with a Straight-Line Source Trajectory. Tsinghua Sci Technol. 2010 Feb; 15(1):56-61. PMID: 20559455; PMCID: PMC2886312.
      Citations: 2     
    53. Bian J, Han X, Sidky EY, Cao G, Lu J, Zhou O, Pan X. Investigation of Sparse Data Mouse Imaging Using Micro-CT with a Carbon-Nanotube-Based X-ray Source. Tsinghua Sci Technol. 2010 Feb 01; 15(1):74-78. PMID: 20582237; PMCID: PMC2891549.
      Citations:    
    54. Cho S, Sidky EY, Bian J, Pan X. Dual-Energy Technique at Low Tube Voltages for Small Animal Imaging. Tsinghua Sci Technol. 2010 Feb; 15(1):79-86. PMID: 20589233; PMCID: PMC2892926.
      Citations:    
    55. Bian J, Xia D, Sidky EY, Pan X. Region of Interest Imaging for a General Trajectory with the Rebinned BPF Algorithm. Tsinghua Sci Technol. 2010 Feb; 15(1):68-73. PMID: 20617122; PMCID: PMC2898485.
      Citations: 1     
    56. Cho S, Xia D, Pellizzari CA, Pan X. A BPF-FBP tandem algorithm for image reconstruction in reverse helical cone-beam CT. Med Phys. 2010 Jan; 37(1):32-9. PMID: 20175463; PMCID: PMC2801731.
      Citations: 1     Fields:    Translation:Humans
    57. Sidky EY, Pan X, Reiser IS, Nishikawa RM, Moore RH, Kopans DB. Enhanced imaging of microcalcifications in digital breast tomosynthesis through improved image-reconstruction algorithms. Med Phys. 2009 Nov; 36(11):4920-32. PMID: 19994501; PMCID: PMC2773453.
      Citations: 56     Fields:    Translation:Humans
    58. Cho S, Pearson E, Pelizzari CA, Pan X. Region-of-interest image reconstruction with intensity weighting in circular cone-beam CT for image-guided radiation therapy. Med Phys. 2009 Apr; 36(4):1184-92. PMID: 19472624; PMCID: PMC2673679.
      Citations: 11     Fields:    Translation:Humans
    59. Xia D, Cho S, Pan X. Image reconstruction in reduced circular sinusoidal cone-beam CT. J Xray Sci Technol. 2009; 17(3):189-205. PMID: 19893212; PMCID: PMC3049156.
      Citations: 2     Fields:    
    60. Sidky EY, Pan X. Analysis of image-reconstruction algorithms for circular, cone-beam CT by Hotelling observer performance on a detection task. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:997-9. PMID: 19964255.
      Citations: 2     Fields:    
    61. Xia D, Bian J, Han X, Sidky EY, Pan X. An Investigation of Compressive-sensing Image Reconstruction from Flying-focal-spot CT Data. IEEE Nucl Sci Symp Conf Rec (1997). 2009 Jan 01; 2009:3458-3462. PMID: 21318098; PMCID: PMC3037815.
      Citations: 2     
    62. Pan X, Sidky EY, Vannier M. Why do commercial CT scanners still employ traditional, filtered back-projection for image reconstruction? Inverse Probl. 2009 Jan 01; 25(12):1230009. PMID: 20376330; PMCID: PMC2849113.
      Citations: 90     
    63. Sharff KA, Song WX, Luo X, Tang N, Luo J, Chen J, Bi Y, He BC, Huang J, Li X, Jiang W, Zhu GH, Su Y, He Y, Shen J, Wang Y, Chen L, Zuo GW, Liu B, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem. 2009 Jan 02; 284(1):649-659. PMID: 18986983; PMCID: PMC2610517.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    64. Sidky EY, Pan X. Image reconstruction in circular cone-beam computed tomography by constrained, total-variation minimization. Phys Med Biol. 2008 Sep 07; 53(17):4777-807. PMID: 18701771; PMCID: PMC2630711.
      Citations: 346     Fields:    Translation:Humans
    65. Pan X, Siewerdsen J, La Riviere PJ, Kalender WA. Anniversary paper. Development of x-ray computed tomography: the role of medical physics and AAPM from the 1970s to present. Med Phys. 2008 Aug; 35(8):3728-39. PMID: 18777932; PMCID: PMC3910137.
      Citations: 13     Fields:    Translation:Humans
    66. Pan X, Siewerdsen J, La Riviere PJ, Kalender WA. Anniversary Paper: Development of x-ray computed tomography: The role of Medical Physics and AAPM from the 1970s to present. Med Phys. 2008 Aug; 35(8):3728-3739. PMID: 28525026.
      Citations:    
    67. Cho S, Xia D, Pelizzari CA, Pan X. Exact reconstruction of volumetric images in reverse helical cone-beam CT. Med Phys. 2008 Jul; 35(7Part1):3030-3040. PMID: 28513025.
      Citations:    
    68. LaRoque SJ, Sidky EY, Pan X. Accurate image reconstruction from few-view and limited-angle data in diffraction tomography. J Opt Soc Am A Opt Image Sci Vis. 2008 Jul; 25(7):1772-82. PMID: 18594635; PMCID: PMC2834797.
      Citations: 24     Fields:    Translation:HumansCells
    69. Cho S, Xia D, Pelizzari CA, Pan X. Exact reconstruction of volumetric images in reverse helical cone-beam CT. Med Phys. 2008 Jul; 35(7):3030-40. PMID: 18697525; PMCID: PMC2673556.
      Citations: 8     Fields:    Translation:Humans
    70. Cho S, Bian J, Pelizzari CA, Chen CT, He TC, Pan X. Region-of-interest image reconstruction in circular cone-beam microCT. Med Phys. 2007 Dec; 34(12):4923-33. PMID: 18196817.
      Citations: 13     Fields:    Translation:HumansAnimals
    71. King M, Giger ML, Suzuki K, Bardo DM, Greenberg B, Lan L, Pan X. Computerized assessment of motion-contaminated calcified plaques in cardiac multidetector CT. Med Phys. 2007 Dec; 34(12):4876-89. PMID: 18196813.
      Citations: 3     Fields:    Translation:Humans
    72. King M, Giger ML, Suzuki K, Pan X. Feature-based characterization of motion-contaminated calcified plaques in cardiac multidetector CT. Med Phys. 2007 Dec; 34(12):4860-75. PMID: 18196812.
      Citations: 3     Fields:    Translation:Humans
    73. King M, Giger ML, Suzuki K, Bardo DME, Greenberg B, Lan L, Pan X. Computerized assessment of motion-contaminated calcified plaques in cardiac multidetector CT. Med Phys. 2007 Dec; 34(12):4876-4889. PMID: 28523813.
      Citations:    
    74. Anastasio MA, Pan X. Region-of-interest imaging in differential phase-contrast tomography. Opt Lett. 2007 Nov 01; 32(21):3167-9. PMID: 17975632.
      Citations: 2     Fields:    
    75. Xia D, Yu L, Sidky EY, Zou Y, Zuo N, Pan X. Noise properties of chord-image reconstruction. IEEE Trans Med Imaging. 2007 Oct; 26(10):1328-44. PMID: 17948724.
      Citations: 5     Fields:    
    76. Anastasio MA, Zou Y, Sidky EY, Pan X. Local cone-beam tomography image reconstruction on chords. J Opt Soc Am A Opt Image Sci Vis. 2007 Jun; 24(6):1569-79. PMID: 17491625.
      Citations: 4     Fields:    
    77. Pan X, Xia D, Halpern H. Targeted-ROI imaging in electron paramagnetic resonance imaging. J Magn Reson. 2007 Jul; 187(1):66-77. PMID: 17451981.
      Citations: 4     Fields:    
    78. Yu L, Zou Y, Sidky EY, Pelizzari CA, Munro P, Pan X. Region of interest reconstruction from truncated data in circular cone-beam CT. IEEE Trans Med Imaging. 2006 Jul; 25(7):869-81. PMID: 16827488.
      Citations: 18     Fields:    Translation:Humans
    79. King M, Pan X, Yu L, Giger M. Region-of-interest reconstruction of motion-contaminated data using a weighted backprojection filtration algorithm. Med Phys. 2006 May; 33(5):1222-38. PMID: 16752557.
      Citations: 2     Fields:    Translation:HumansCells
    80. Zou Y, Pan X, Sidky EY. Theory and algorithms for image reconstruction on chords and within regions of interest. J Opt Soc Am A Opt Image Sci Vis. 2005 Nov; 22(11):2372-84. PMID: 16304723.
      Citations: 15     Fields:    Translation:Humans
    81. Anastasio MA, Zhang J, Sidky EY, Zou Y, Xia D, Pan X. Feasibility of half-data image reconstruction in 3-D reflectivity tomography with a spherical aperture. IEEE Trans Med Imaging. 2005 Sep; 24(9):1100-12. PMID: 16156349.
      Citations: 7     Fields:    
    82. Zou Y, Pan X, Xia D, Wang G. PI-line-based image reconstruction in helical cone-beam computed tomography with a variable pitch. Med Phys. 2005 Aug; 32(8):2639-48. PMID: 16193794.
      Citations: 1     Fields:    
    83. Williams BB, Pan X, Halpern HJ. EPR imaging: the relationship between CW spectra acquired from an extended sample subjected to fixed stepped gradients and the Radon transform of the resonance density. J Magn Reson. 2005 May; 174(1):88-96. PMID: 15809176.
      Citations: 11     Fields:    
    84. Pan X, Zou Y, Xia D, Sidky EY. Reconstruction of 3D regions-of-interest from data in reduced helical cone-beam scans. Technol Cancer Res Treat. 2005 Apr; 4(2):143-50. PMID: 15773783.
      Citations:    Fields:    
    85. Sidky EY, Zou Y, Pan X. Minimum data image reconstruction algorithms with shift-invariant filtering for helical, cone-beam CT. Phys Med Biol. 2005 Apr 21; 50(8):1643-57. PMID: 15815087.
      Citations: 4     Fields:    Translation:Humans
    86. Pan X, Zou Y, Xia D. Image reconstruction in peripheral and central regions-of-interest and data redundancy. Med Phys. 2005 Mar; 32(3):673-84. PMID: 15839339.
      Citations: 26     Fields:    Translation:Humans
    87. Pan X, Yu L, Kao CM. Spatial-resolution enhancement in computed tomography. IEEE Trans Med Imaging. 2005 Feb; 24(2):246-53. PMID: 15707250.
      Citations:    Fields:    
    88. Anastasio MA, Zhang J, Pan X, Zou Y, Ku G, Wang LV. Half-time image reconstruction in thermoacoustic tomography. IEEE Trans Med Imaging. 2005 Feb; 24(2):199-210. PMID: 15707246.
      Citations: 41     Fields:    Translation:Animals
    89. Zou Y, Pan X, Sidky EY. Image reconstruction in regions-of-interest from truncated projections in a reduced fan-beam scan. Phys Med Biol. 2005 Jan 07; 50(1):13-27. PMID: 15715419.
      Citations: 21     Fields:    
    90. Xia D, Roeske JC, Yu L, Pelizzari CA, Mundt AJ, Pan X. A hybrid approach to reducing computed tomography metal artifacts in intracavitary brachytherapy. Brachytherapy. 2005; 4(1):18-23. PMID: 15737902.
      Citations: 14     Fields:    
    91. Zou Y, Pan X. An extended data function and its generalized backprojection for image reconstruction in helical cone-beam CT. Phys Med Biol. 2004 Nov 21; 49(22):N383-7. PMID: 15609569.
      Citations: 9     Fields:    
    92. Pan X, Xia D, Zou Y, Yu L. A unified analysis of FBP-based algorithms in helical cone-beam and circular cone- and fan-beam scans. Phys Med Biol. 2004 Sep 21; 49(18):4349-69. PMID: 15509070.
      Citations: 6     Fields:    
    93. Zou Y, Pan X. Image reconstruction on PI-lines by use of filtered backprojection in helical cone-beam CT. Phys Med Biol. 2004 Jun 21; 49(12):2717-31. PMID: 15272684.
      Citations: 9     Fields:    
    94. Kao CM, Pan X, Chen CT. An exact Fourier rebinning algorithm for 3D PET imaging using panel detectors. Phys Med Biol. 2004 Jun 07; 49(11):2407-23. PMID: 15248586.
      Citations: 3     Fields:    
    95. Zou Y, Sidky EY, Pan X. Partial volume and aliasing artefacts in helical cone-beam CT. Phys Med Biol. 2004 Jun 07; 49(11):2365-75. PMID: 15248583.
      Citations: 8     Fields:    Translation:Humans
    96. Sidky EY, Zou Y, Pan X. Impact of polychromatic x-ray sources on helical, cone-beam computed tomography and dual-energy methods. Phys Med Biol. 2004 Jun 07; 49(11):2293-303. PMID: 15248578.
      Citations: 6     Fields:    Translation:Humans
    97. Pan X, La Rivière PJ. Sampling and aliasing consequences of quarter-detector offset use in helical CT. IEEE Trans Med Imaging. 2004 Jun; 23(6):738-49. PMID: 15191148.
      Citations: 7     Fields:    Translation:Humans
    98. Zou Y, Pan X. Exact image reconstruction on PI-lines from minimum data in helical cone-beam CT. Phys Med Biol. 2004 Mar 21; 49(6):941-59. PMID: 15104318.
      Citations: 48     Fields:    Translation:Humans
    99. Anastasio MA, Shi D, De Carlo F, Pan X. Analytic image reconstruction in local phase-contrast tomography. Phys Med Biol. 2004 Jan 07; 49(1):121-44. PMID: 14971777.
      Citations: 5     Fields:    Translation:Humans
    100. Anastasio MA, Shi D, Pan X, Pelizzari C, Munro P. A preliminary investigation of local tomography for megavoltage CT imaging. Med Phys. 2003 Nov; 30(11):2969-80. PMID: 14655944.
      Citations: 2     Fields:    Translation:Humans
    101. Yu L, Pan X. Half-scan fan-beam computed tomography with improved noise and resolution properties. Med Phys. 2003 Oct; 30(10):2629-37. PMID: 14596299.
      Citations: 5     Fields:    
    102. Pan X, Yu L. Image reconstruction with shift-variant filtration and its implication for noise and resolution properties in fan-beam computed tomography. Med Phys. 2003 Apr; 30(4):590-600. PMID: 12722811.
      Citations: 16     Fields:    
    103. Anastasio MA, Pan X. An improved reconstruction algorithm for 3-D diffraction tomography using spherical-wave sources. IEEE Trans Biomed Eng. 2003 Apr; 50(4):517-21. PMID: 12723064.
      Citations:    Fields:    
    104. Roeske JC, Lund C, Pelizzari CA, Pan X, Mundt AJ. Reduction of computed tomography metal artifacts due to the Fletcher-Suit applicator in gynecology patients receiving intracavitary brachytherapy. Brachytherapy. 2003; 2(4):207-14. PMID: 15062128.
      Citations: 8     Fields:    Translation:Humans
    105. Pan X, Zou Y, Anastasio MA. Data redundancy and reduced-scan reconstruction in reflectivity tomography. IEEE Trans Image Process. 2003; 12(7):784-95. PMID: 18237953.
      Citations: 7     Fields:    
    106. Pan X, La Rivière PJ. Longitudinal aliasing in multislice helical computed tomography: sampling and cone-beam effects. IEEE Trans Med Imaging. 2002 Nov; 21(11):1366-73. PMID: 12575873.
      Citations: 2     Fields:    
    107. Pan X, La Rivière PJ. Pitch dependence of longitudinal sampling and aliasing effects in multi-slice helical computed tomography (CT). Phys Med Biol. 2002 Aug 07; 47(15):2797-810. PMID: 12200940.
      Citations: 1     Fields:    
    108. Pan X, Sidky EY, Kao CM, Zou Y, Metz CE. Short-scan SPECT imaging with non-uniform attenuation and 3D distance-dependent spatial resolution. Phys Med Biol. 2002 Aug 07; 47(15):2811-33. PMID: 12200941.
      Citations: 1     Fields:    Translation:Humans
    109. Du W, Karczmar GS, Pan X. Effects of constant frequency noise in magnetic resonance imaging with nonuniform k-space sampling. Med Phys. 2002 Aug; 29(8):1832-8. PMID: 12201430.
      Citations:    Fields:    Translation:Animals
    110. Pan X, La Rivière PJ. Anti-aliasing weighting functions for single-slice helical CT. IEEE Trans Med Imaging. 2002 Aug; 21(8):978-90. PMID: 12472270.
      Citations: 1     Fields:    
    111. Pan X, La Rivière PJ. Favorable noise uniformity properties of Fourier-based interpolation and reconstruction approaches in single-slice helical computed tomography. Med Phys. 2002 Jun; 29(6):943-51. PMID: 12094989.
      Citations: 4     Fields:    Translation:Humans
    112. Pan X, La Rivière PJ. Fourier-based approach to interpolation in single-slice helical computed tomography. Med Phys. 2001 Mar; 28(3):381-92. PMID: 11318320.
      Citations:    Fields:    
    113. Kao CM, Pan X. Non-iterative methods incorporating a priori source distribution and data information for suppression of image noise and artefacts in 3D SPECT. Phys Med Biol. 2000 Oct; 45(10):2801-19. PMID: 11049173.
      Citations:    Fields:    
    114. Pan X. Fast reconstruction with uniform noise properties in halfscan computed tomography. Med Phys. 2000 Sep; 27(9):2031-6. PMID: 11011730.
      Citations: 2     Fields:    Translation:Humans
    115. Pan X, La Rivière PJ. Nonparametric regression sinogram smoothing using a roughness-penalized Poisson likelihood objective function. IEEE Trans Med Imaging. 2000 Aug; 19(8):773-86. PMID: 11055801.
      Citations: 1     Fields:    Translation:Humans
    116. Anastasio MA, Pan X. Computationally efficient and statistically robust image reconstruction in three-dimensional diffraction tomography. J Opt Soc Am A Opt Image Sci Vis. 2000 Mar; 17(3):391-400. PMID: 10708019.
      Citations:    Fields:    
    117. Anastasio MA, Pan X. A new reconstruction approach for reflection mode diffraction tomography. IEEE Trans Image Process. 2000; 9(7):1262-71. PMID: 18262963.
      Citations:    Fields:    
    118. Pan X, Anastasio MA. Minimal-scan filtered backpropagation algorithms for diffraction tomography. J Opt Soc Am A Opt Image Sci Vis. 1999 Dec; 16(12):2896-903. PMID: 10621970.
      Citations: 1     Fields:    
    119. Pan X. Optimal noise control in and fast reconstruction of fan-beam computed tomography image. Med Phys. 1999 May; 26(5):689-97. PMID: 10360528.
      Citations: 13     Fields:    
    120. Pan X. Unified reconstruction theory for diffraction tomography, with consideration of noise control. J Opt Soc Am A Opt Image Sci Vis. 1998 Sep; 15(9):2312-26. PMID: 9729852.
      Citations: 2     Fields:    
    121. Pan X. Quasi-bandlimited properties of radon transforms and their implications for increasing angular sampling densities. IEEE Trans Med Imaging. 1998 Jun; 17(3):395-406. PMID: 9735903.
      Citations: 1     Fields:    
    122. Kao CM, Pan X, Chen CT, Wong WH. Image restoration and reconstruction with a Bayesian approach. Med Phys. 1998 May; 25(5):600-13. PMID: 9608469.
      Citations: 4     Fields:    Translation:Humans
    123. Pan X. A general approach for multidimensional smoothing. Med Phys. 1998 Apr; 25(4):562-70. PMID: 9571624.
      Citations: 1     Fields:    Translation:Humans
    124. Pan X, Metz CE. The "proper" binormal model: parametric receiver operating characteristic curve estimation with degenerate data. Acad Radiol. 1997 May; 4(5):380-9. PMID: 9156236.
      Citations: 30     Fields:    Translation:Humans
    125. Aarsvold JN, Mintzer RA, Yasillo NJ, Heimsath SJ, Block TA, Matthews KL, Pan X, Wu C, Beck RN, Chen CT, et al. A miniature gamma camera. Ann N Y Acad Sci. 1994 May 31; 720:192-205. PMID: 8010638.
      Citations: 1     Fields:    Translation:Humans
    126. Aarsvold JN, Mintzer RA, Yasillo NJ, Heimsath SJ, Block TA, Matthews KL, Pan X, Wu C, Beck RN, Chen CT, Cooper M. A Miniature Gamma Cameraa. Ann N Y Acad Sci. 1994 May; 720(1):192-205. PMID: 28621865.
      Citations:    Fields:    
    127. Pan X, Wong WH, Chen CT, Liu J. Correction for photon attenuation in SPECT: analytical framework, average attenuation factors, and a new hybrid approach. Phys Med Biol. 1993 Sep; 38(9):1219-34. PMID: 8415901.
      Citations: 1     Fields:    
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