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Eve Van Cauter

TitleEmeritus/Emerita, Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Endocrinology
AddressChicago IL 60637
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    Collapse Research 
    Collapse research activities and funding
    U01DK094431     (EHRMANN, DAVID A)Sep 21, 2011 - Jun 30, 2019
    NIH
    Enhancement of Beta Cell Function with Pharmacologic and Sleep Apnea Treatment
    Role: Co-Principal Investigator
    R01OH009482     (VAN CAUTER, EVE)Sep 1, 2009 - Aug 31, 2015
    NIH
    Cardiometabolic Risk of Shift Work: Sleep Loss vs. Circadian Disruption
    Role: Principal Investigator
    R01DK071696     (VAN CAUTER, EVE)Sep 15, 2005 - Aug 31, 2011
    NIH
    Sleep Disturbance as a Nontraditional Risk Factor in CKD
    Role: Principal Investigator
    R01HL072694     (VAN CAUTER, EVE)Jul 1, 2002 - Apr 30, 2008
    NIH
    EXTENDED WORK SCHEDULE AND HEALTH: ROLE OF SLEEP LOSS
    Role: Principal Investigator
    T32HL007909     (TUREK, FRED W)Jul 1, 1998 - Feb 28, 2025
    NIH
    Training Grant in Circadian and Sleep Research
    Role: Co-Principal Investigator
    P01AG011412     (ZEE, PHYLLIS C.)Sep 1, 1994 - Jun 30, 2022
    NIH
    Alterations of Sleep and Circadian Timing in Aging
    Role: Co-Principal Investigator
    R01DK041814     (VAN CAUTER, EVE)Jul 1, 1989 - Apr 30, 2005
    NIH
    SLEEP AND CIRCADIAN RHYTHMICITY IN GLUCOSE REGULATION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cable J, Schernhammer E, Hanlon EC, Vetter C, Cedernaes J, Makarem N, Dashti HS, Shechter A, Depner C, Ingiosi A, Blume C, Tan X, Gottlieb E, Benedict C, Van Cauter E, St-Onge MP. Sleep and circadian rhythms: pillars of health-a Keystone Symposia report. Ann N Y Acad Sci. 2021 12; 1506(1):18-34. PMID: 34341993; PMCID: PMC8688158.
      Citations: 6     Fields:    Translation:HumansAnimals
    2. Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S, Nadeau KJ, Hannon TS, Manchanda S, Mather KJ, Kahn SE, Ehrmann DA, Van Cauter E, RISE Consortium. Obstructive Sleep Apnea, Glucose Tolerance, and ?-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 04; 44(4):993-1001. PMID: 33547205; PMCID: PMC7985427.
      Citations: 7     Fields:    Translation:Humans
    3. Hanlon EC, Leproult R, Stuhr KL, Doncheck EM, Hillard CJ, Van Cauter E. Circadian Misalignment of the 24-hour Profile of Endocannabinoid 2-Arachidonoylglycerol (2-AG) in Obese Adults. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31970413; PMCID: PMC7015463.
      Citations: 3     Fields:    Translation:Humans
    4. Sletten TL, Cappuccio FP, Davidson AJ, Van Cauter E, Rajaratnam SMW, Scheer FAJL. Health consequences of circadian disruption. Sleep. 2020 01 13; 43(1). PMID: 31930347; PMCID: PMC7368337.
      Citations: 12     Fields:    
    5. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E, RISE Consortium. The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes. Pediatr Diabetes. 2019 12; 20(8):1056-1063. PMID: 31486162; PMCID: PMC7199716.
      Citations: 4     Fields:    Translation:Humans
    6. Ikegami K, Refetoff S, Van Cauter E, Yoshimura T. Interconnection between circadian clocks and thyroid function. Nat Rev Endocrinol. 2019 10; 15(10):590-600. PMID: 31406343; PMCID: PMC7288350.
      Citations: 51     Fields:    Translation:HumansAnimals
    7. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider KM, Nadeau KJ, Hannon TS, Sam S, Barengolts E, Manchanda S, Ehrmann DA, Van Cauter E, RISE Consortium. Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes. Diabetes Care. 2019 07; 42(7):1326-1332. PMID: 31048411; PMCID: PMC6609965.
      Citations: 21     Fields:    Translation:Humans
    8. Carter JR, Grimaldi D, Fonkoue IT, Medalie L, Mokhlesi B, Van Cauter E. Assessment of sympathetic neural activity in chronic insomnia: evidence for elevated cardiovascular risk. Sleep. 2018 09 01; 41(9). PMID: 29992317; PMCID: PMC6132622.
      Citations: 7     Fields:    
    9. Gehlbach BK, Patel SB, Van Cauter E, Pohlman AS, Hall JB, Zabner J. The Effects of Timed Light Exposure in Critically Ill Patients: A Randomized Controlled Pilot Clinical Trial. Am J Respir Crit Care Med. 2018 07 15; 198(2):275-278. PMID: 29529381; PMCID: PMC6058987.
      Citations: 5     Fields:    Translation:Humans
    10. Morselli LL, Temple KA, Leproult R, Ehrmann DA, Van Cauter E, Mokhlesi B. Determinants of Slow-Wave Activity in Overweight and Obese Adults: Roles of Sex, Obstructive Sleep Apnea and Testosterone Levels. Front Endocrinol (Lausanne). 2018; 9:377. PMID: 30050500; PMCID: PMC6052085.
      Citations: 3     Fields:    
    11. Temple KA, Leproult R, Morselli L, Ehrmann DA, Van Cauter E, Mokhlesi B. Sex Differences in the Impact of Obstructive Sleep Apnea on Glucose Metabolism. Front Endocrinol (Lausanne). 2018; 9:376. PMID: 30042734; PMCID: PMC6048262.
      Citations: 9     Fields:    
    12. Reutrakul S, Van Cauter E. Sleep influences on obesity, insulin resistance, and risk of type 2 diabetes. Metabolism. 2018 07; 84:56-66. PMID: 29510179.
      Citations: 108     Fields:    Translation:Humans
    13. Morselli LL, Gamazon ER, Tasali E, Cox NJ, Van Cauter E, Davis LK. Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study. Diabetes. 2018 01; 67(1):155-164. PMID: 29084784; PMCID: PMC5741150.
      Citations: 1     Fields:    Translation:Humans
    14. Ricardo AC, Knutson K, Chen J, Appel LJ, Bazzano L, Carmona-Powell E, Cohan J, Kurella Tamura M, Steigerwalt S, Thornton JD, Weir M, Turek NF, Rahman M, Van Cauter E, Lash JP, Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. The Association of Sleep Duration and Quality with CKD Progression. J Am Soc Nephrol. 2017 12; 28(12):3708-3715. PMID: 28912373; PMCID: PMC5698066.
      Citations: 24     Fields:    Translation:Humans
    15. Knutson KL, Lash J, Ricardo AC, Herdegen J, Thornton JD, Rahman M, Turek N, Cohan J, Appel LJ, Bazzano LA, Tamura MK, Steigerwalt SP, Weir MR, Van Cauter E, Cric Study Investigators. Habitual sleep and kidney function in chronic kidney disease: the Chronic Renal Insufficiency Cohort study. J Sleep Res. 2018 04; 27(2):281-289. PMID: 28643350; PMCID: PMC6480301.
      Citations: 13     Fields:    Translation:Humans
    16. Guyon A, Morselli LL, Balbo ML, Tasali E, Leproult R, L'Hermite-Bal?riaux M, Van Cauter E, Spiegel K. Effects of Insufficient Sleep on Pituitary-Adrenocortical Response to CRH Stimulation in Healthy Men. Sleep. 2017 06 01; 40(6). PMID: 28444400; PMCID: PMC6075556.
      Citations: 11     Fields:    Translation:HumansAnimalsCTClinical Trials
    17. Oster H, Challet E, Ott V, Arvat E, de Kloet ER, Dijk DJ, Lightman S, Vgontzas A, Van Cauter E. The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids. Endocr Rev. 2017 02 01; 38(1):3-45. PMID: 27749086; PMCID: PMC5563520.
      Citations: 159     Fields:    Translation:HumansAnimals
    18. Mokhlesi B, Grimaldi D, Beccuti G, Van Cauter E. Effect of one week of CPAP treatment of obstructive sleep apnoea on 24-hour profiles of glucose, insulin and counter-regulatory hormones in type 2 diabetes. Diabetes Obes Metab. 2017 03; 19(3):452-456. PMID: 27860160.
      Citations: 27     Fields:    Translation:Humans
    19. DePietro RH, Knutson KL, Spampinato L, Anderson SL, Meltzer DO, Van Cauter E, Arora VM. Association Between Inpatient Sleep Loss and Hyperglycemia of Hospitalization. Diabetes Care. 2017 Feb; 40(2):188-193. PMID: 27903614; PMCID: PMC5250691.
      Citations: 19     Fields:    Translation:Humans
    20. Broussard JL, Van Cauter E. Disturbances of sleep and circadian rhythms: novel risk factors for obesity. Curr Opin Endocrinol Diabetes Obes. 2016 10; 23(5):353-9. PMID: 27584008; PMCID: PMC5070789.
      Citations: 65     Fields:    Translation:Humans
    21. Mokhlesi B, Grimaldi D, Beccuti G, Abraham V, Whitmore H, Delebecque F, Van Cauter E. Effect of One Week of 8-Hour Nightly Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea on Glycemic Control in Type 2 Diabetes: A Proof-of-Concept Study. Am J Respir Crit Care Med. 2016 08 15; 194(4):516-9. PMID: 27525461; PMCID: PMC5003331.
      Citations: 26     Fields:    Translation:Humans
    22. Grimaldi D, Carter JR, Van Cauter E, Leproult R. Adverse Impact of Sleep Restriction and Circadian Misalignment on Autonomic Function in Healthy Young Adults. Hypertension. 2016 07; 68(1):243-50. PMID: 27271308; PMCID: PMC4902172.
      Citations: 43     Fields:    Translation:Humans
    23. Hanlon EC, Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E. Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. Sleep. 2016 Mar 01; 39(3):653-64. PMID: 26612385; PMCID: PMC4763355.
      Citations: 43     Fields:    Translation:Humans
    24. Arble DM, Bass J, Behn CD, Butler MP, Challet E, Czeisler C, Depner CM, Elmquist J, Franken P, Grandner MA, Hanlon EC, Keene AC, Joyner MJ, Karatsoreos I, Kern PA, Klein S, Morris CJ, Pack AI, Panda S, Ptacek LJ, Punjabi NM, Sassone-Corsi P, Scheer FA, Saxena R, Seaquest ER, Thimgan MS, Van Cauter E, Wright KP. Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions. Sleep. 2015 Dec 01; 38(12):1849-60. PMID: 26564131; PMCID: PMC4667373.
      Citations: 64     Fields:    Translation:HumansAnimals
    25. Anothaisintawee T, Reutrakul S, Van Cauter E, Thakkinstian A. Sleep disturbances compared to traditional risk factors for diabetes development: Systematic review and meta-analysis. Sleep Med Rev. 2016 12; 30:11-24. PMID: 26687279.
      Citations: 179     Fields:    Translation:Humans
    26. Van Someren EJ, Cirelli C, Dijk DJ, Van Cauter E, Schwartz S, Chee MW. Disrupted Sleep: From Molecules to Cognition. J Neurosci. 2015 Oct 14; 35(41):13889-95. PMID: 26468189; PMCID: PMC4604227.
      Citations: 30     Fields:    Translation:Humans
    27. Beveridge C, Knutson K, Spampinato L, Flores A, Meltzer DO, Van Cauter E, Arora VM. Daytime Physical Activity and Sleep in Hospitalized Older Adults: Association with Demographic Characteristics and Disease Severity. J Am Geriatr Soc. 2015 Jul; 63(7):1391-400. PMID: 26131982; PMCID: PMC4752005.
      Citations: 17     Fields:    Translation:Humans
    28. Laposky AD, Van Cauter E, Diez-Roux AV. Reducing health disparities: the role of sleep deficiency and sleep disorders. Sleep Med. 2016 Feb; 18:3-6. PMID: 26431756; PMCID: PMC4603998.
      Citations: 45     Fields:    Translation:Humans
    29. Mokhlesi B, Finn LA, Hagen EW, Young T, Hla KM, Van Cauter E, Peppard PE. Obstructive sleep apnea during REM sleep and hypertension. results of the Wisconsin Sleep Cohort. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):1158-67. PMID: 25295854; PMCID: PMC4299639.
      Citations: 120     Fields:    Translation:Humans
    30. Reutrakul S, Van Cauter E. Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes. Ann N Y Acad Sci. 2014 Apr; 1311:151-73. PMID: 24628249.
      Citations: 110     Fields:    Translation:Humans
    31. Leproult R, Holmb?ck U, Van Cauter E. Circadian misalignment augments markers of insulin resistance and inflammation, independently of sleep loss. Diabetes. 2014 Jun; 63(6):1860-9. PMID: 24458353; PMCID: PMC4030107.
      Citations: 242     Fields:    Translation:Humans
    32. Mokhlesi B, Grimaldi D, Van Cauter E. Response to comment on Grimaldi et al. Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications. Diabetes Care 2014;37:355-363. Diabetes Care. 2014; 37(3):e60-1. PMID: 24558089; PMCID: PMC3931385.
      Citations: 2     Fields:    Translation:Humans
    33. Grimaldi D, Beccuti G, Touma C, Van Cauter E, Mokhlesi B. Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications. Diabetes Care. 2014 Feb; 37(2):355-63. PMID: 24101701; PMCID: PMC3898763.
      Citations: 81     Fields:    Translation:Humans
    34. Reutrakul S, Zaidi N, Wroblewski K, Kay HH, Ismail M, Ehrmann DA, Van Cauter E. Interactions between pregnancy, obstructive sleep apnea, and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):4195-202. PMID: 23966237; PMCID: PMC3790617.
      Citations: 30     Fields:    Translation:Humans
    35. Reutrakul S, Hood MM, Crowley SJ, Morgan MK, Teodori M, Knutson KL, Van Cauter E. Chronotype is independently associated with glycemic control in type 2 diabetes. Diabetes Care. 2013 Sep; 36(9):2523-9. PMID: 23637357; PMCID: PMC3747872.
      Citations: 100     Fields:    Translation:Humans
    36. Morselli LL, Nedeltcheva A, Leproult R, Spiegel K, Martino E, Legros JJ, Weiss RE, Mockel J, Van Cauter E, Copinschi G. Impact of GH replacement therapy on sleep in adult patients with GH deficiency of pituitary origin. Eur J Endocrinol. 2013 May; 168(5):763-70. PMID: 23447518; PMCID: PMC3832204.
      Citations: 9     Fields:    Translation:Humans
    37. Broussard JL, Ehrmann DA, Van Cauter E, Tasali E, Brady MJ. Impaired insulin signaling in human adipocytes after experimental sleep restriction: a randomized, crossover study. Ann Intern Med. 2012 Oct 16; 157(8):549-57. PMID: 23070488; PMCID: PMC4435718.
      Citations: 149     Fields:    Translation:HumansCells
    38. Gehlbach BK, Chapotot F, Leproult R, Whitmore H, Poston J, Pohlman M, Miller A, Pohlman AS, Nedeltcheva A, Jacobsen JH, Hall JB, Van Cauter E. Temporal disorganization of circadian rhythmicity and sleep-wake regulation in mechanically ventilated patients receiving continuous intravenous sedation. Sleep. 2012 Aug 01; 35(8):1105-14. PMID: 22851806; PMCID: PMC3397814.
      Citations: 56     Fields:    Translation:Humans
    39. Van Cauter E. Sleep disturbances and insulin resistance. Diabet Med. 2011 Dec; 28(12):1455-62. PMID: 21950773.
      Citations: 41     Fields:    Translation:Humans
    40. Arora VM, Chang KL, Fazal AZ, Staisiunas PG, Meltzer DO, Zee PC, Knutson KL, Van Cauter E. Objective sleep duration and quality in hospitalized older adults: associations with blood pressure and mood. J Am Geriatr Soc. 2011 Nov; 59(11):2185-6. PMID: 22098044; PMCID: PMC3273961.
      Citations: 20     Fields:    Translation:Humans
    41. Reutrakul S, Zaidi N, Wroblewski K, Kay HH, Ismail M, Ehrmann DA, Van Cauter E. Sleep disturbances and their relationship to glucose tolerance in pregnancy. Diabetes Care. 2011 Nov; 34(11):2454-7. PMID: 21926292; PMCID: PMC3198297.
      Citations: 47     Fields:    Translation:Humans
    42. Hanlon EC, Van Cauter E. Quantification of sleep behavior and of its impact on the cross-talk between the brain and peripheral metabolism. Proc Natl Acad Sci U S A. 2011 Sep 13; 108 Suppl 3:15609-16. PMID: 21852576; PMCID: PMC3176603.
      Citations: 48     Fields:    Translation:Humans
    43. Leproult R, Van Cauter E. Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA. 2011 Jun 01; 305(21):2173-4. PMID: 21632481; PMCID: PMC4445839.
      Citations: 70     Fields:    Translation:Humans
    44. Knutson KL, Van Cauter E, Zee P, Liu K, Lauderdale DS. Cross-sectional associations between measures of sleep and markers of glucose metabolism among subjects with and without diabetes: the Coronary Artery Risk Development in Young Adults (CARDIA) Sleep Study. Diabetes Care. 2011 May; 34(5):1171-6. PMID: 21411507; PMCID: PMC3114508.
      Citations: 103     Fields:    Translation:Humans
    45. Spiegel K, Tasali E, Leproult R, Scherberg N, Van Cauter E. Twenty-four-hour profiles of acylated and total ghrelin: relationship with glucose levels and impact of time of day and sleep. J Clin Endocrinol Metab. 2011 Feb; 96(2):486-93. PMID: 21106712; PMCID: PMC3206394.
      Citations: 47     Fields:    Translation:HumansCells
    46. Van Cauter E, Ehrmann DA. Sleep and metabolism. Preface. Best Pract Res Clin Endocrinol Metab. 2010 Oct; 24(5):vii-viii. PMID: 21112018.
      Citations: 2     Fields:    Translation:HumansAnimals
    47. Balbo M, Leproult R, Van Cauter E. Impact of sleep and its disturbances on hypothalamo-pituitary-adrenal axis activity. Int J Endocrinol. 2010; 2010:759234. PMID: 20628523; PMCID: PMC2902103.
      Citations: 95     
    48. Copinschi G, Nedeltcheva A, Leproult R, Morselli LL, Spiegel K, Martino E, Legros JJ, Weiss RE, Mockel J, Van Cauter E. Sleep disturbances, daytime sleepiness, and quality of life in adults with growth hormone deficiency. J Clin Endocrinol Metab. 2010 May; 95(5):2195-202. PMID: 20332249; PMCID: PMC2869538.
      Citations: 11     Fields:    Translation:Humans
    49. Knutson KL, Van Cauter E, Rathouz PJ, DeLeire T, Lauderdale DS. Trends in the prevalence of short sleepers in the USA: 1975-2006. Sleep. 2010 Jan; 33(1):37-45. PMID: 20120619; PMCID: PMC2802246.
      Citations: 130     Fields:    Translation:Humans
    50. Aronsohn RS, Whitmore H, Van Cauter E, Tasali E. Impact of untreated obstructive sleep apnea on glucose control in type 2 diabetes. Am J Respir Crit Care Med. 2010 Mar 01; 181(5):507-13. PMID: 20019340; PMCID: PMC2830401.
      Citations: 153     Fields:    Translation:Humans
    51. Leproult R, Van Cauter E. Role of sleep and sleep loss in hormonal release and metabolism. Endocr Dev. 2010; 17:11-21. PMID: 19955752; PMCID: PMC3065172.
      Citations: 173     Fields:    Translation:HumansAnimals
    52. Knutson KL, Van Cauter E, Rathouz PJ, Yan LL, Hulley SB, Liu K, Lauderdale DS. Association between sleep and blood pressure in midlife: the CARDIA sleep study. Arch Intern Med. 2009 Jun 08; 169(11):1055-61. PMID: 19506175; PMCID: PMC2944774.
      Citations: 157     Fields:    Translation:Humans
    53. Spiegel K, Tasali E, Leproult R, Van Cauter E. Effects of poor and short sleep on glucose metabolism and obesity risk. Nat Rev Endocrinol. 2009 May; 5(5):253-61. PMID: 19444258; PMCID: PMC4457292.
      Citations: 310     Fields:    Translation:Humans
    54. Van Cauter E, Spiegel K, Tasali E, Leproult R. Metabolic consequences of sleep and sleep loss. Sleep Med. 2008 Sep; 9 Suppl 1:S23-8. PMID: 18929315; PMCID: PMC4444051.
      Citations: 232     Fields:    Translation:HumansCells
    55. Van Cauter E, Knutson KL. Sleep and the epidemic of obesity in children and adults. Eur J Endocrinol. 2008 Dec; 159 Suppl 1:S59-66. PMID: 18719052; PMCID: PMC2755992.
      Citations: 147     Fields:    Translation:HumansPHPublic Health
    56. Tasali E, Van Cauter E, Hoffman L, Ehrmann DA. Impact of obstructive sleep apnea on insulin resistance and glucose tolerance in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Oct; 93(10):3878-84. PMID: 18647805; PMCID: PMC2579653.
      Citations: 27     Fields:    Translation:Humans
    57. Tasali E, Van Cauter E, Ehrmann DA. Polycystic Ovary Syndrome and Obstructive Sleep Apnea. Sleep Med Clin. 2008 Mar; 3(1):37-46. PMID: 19255602; PMCID: PMC2390828.
      Citations: 24     Fields:    
    58. Tasali E, Mokhlesi B, Van Cauter E. Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest. 2008 Feb; 133(2):496-506. PMID: 18252916.
      Citations: 161     Fields:    Translation:Humans
    59. Tasali E, Leproult R, Ehrmann DA, Van Cauter E. Slow-wave sleep and the risk of type 2 diabetes in humans. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):1044-9. PMID: 18172212; PMCID: PMC2242689.
      Citations: 349     Fields:    Translation:Humans
    60. Knutson KL, Van Cauter E. Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci. 2008; 1129:287-304. PMID: 18591489; PMCID: PMC4394987.
      Citations: 282     Fields:    Translation:Humans
    61. Knutson KL, Spiegel K, Penev P, Van Cauter E. The metabolic consequences of sleep deprivation. Sleep Med Rev. 2007 Jun; 11(3):163-78. PMID: 17442599; PMCID: PMC1991337.
      Citations: 401     Fields:    Translation:Humans
    62. Van Cauter E, Holmback U, Knutson K, Leproult R, Miller A, Nedeltcheva A, Pannain S, Penev P, Tasali E, Spiegel K. Impact of sleep and sleep loss on neuroendocrine and metabolic function. Horm Res. 2007; 67 Suppl 1:2-9. PMID: 17308390.
      Citations: 94     Fields:    Translation:Humans
    63. Knutson KL, Ryden AM, Mander BA, Van Cauter E. Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus. Arch Intern Med. 2006 Sep 18; 166(16):1768-74. PMID: 16983057.
      Citations: 226     Fields:    Translation:Humans
    64. Latta F, Leproult R, Tasali E, Hofmann E, Van Cauter E. Sex differences in delta and alpha EEG activities in healthy older adults. Sleep. 2005 Dec; 28(12):1525-34. PMID: 16408411.
      Citations: 23     Fields:    Translation:Humans
    65. Latta F, Leproult R, Tasali E, Hofmann E, L'Hermite-Bal?riaux M, Copinschi G, Van Cauter E. Sex differences in nocturnal growth hormone and prolactin secretion in healthy older adults: relationships with sleep EEG variables. Sleep. 2005 Dec; 28(12):1519-24. PMID: 16408410.
      Citations: 14     Fields:    Translation:Humans
    66. Spiegel K, Knutson K, Leproult R, Tasali E, Van Cauter E. Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. J Appl Physiol (1985). 2005 Nov; 99(5):2008-19. PMID: 16227462.
      Citations: 395     Fields:    Translation:Humans
    67. Tasali E, Van Cauter E, Ehrmann DA. Relationships between sleep disordered breathing and glucose metabolism in polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jan; 91(1):36-42. PMID: 16219719.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    68. Leproult R, Van Onderbergen A, L'hermite-Bal?riaux M, Van Cauter E, Copinschi G. Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men. Clin Endocrinol (Oxf). 2005 Sep; 63(3):298-304. PMID: 16117817.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    69. Penev P, Spiegel K, Marcinkowski T, Van Cauter E. Impact of carbohydrate-rich meals on plasma epinephrine levels: dysregulation with aging. J Clin Endocrinol Metab. 2005 Nov; 90(11):6198-206. PMID: 16091491.
      Citations: 20     Fields:    Translation:Humans
    70. Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004 Dec 07; 141(11):846-50. PMID: 15583226.
      Citations: 786     Fields:    Translation:HumansCTClinical Trials
    71. Spiegel K, Leproult R, L'hermite-Bal?riaux M, Copinschi G, Penev PD, Van Cauter E. Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab. 2004 Nov; 89(11):5762-71. PMID: 15531540.
      Citations: 348     Fields:    Translation:HumansCells
    72. Van Cauter E, Latta F, Nedeltcheva A, Spiegel K, Leproult R, Vandenbril C, Weiss R, Mockel J, Legros JJ, Copinschi G. Reciprocal interactions between the GH axis and sleep. Growth Horm IGF Res. 2004 Jun; 14 Suppl A:S10-7. PMID: 15135771.
      Citations: 28     Fields:    Translation:Humans
    73. Burgess HJ, Penev PD, Schneider R, Van Cauter E. Estimating cardiac autonomic activity during sleep: impedance cardiography, spectral analysis, and Poincar? plots. Clin Neurophysiol. 2004 Jan; 115(1):19-28. PMID: 14706465.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    74. Buxton OM, Lee CW, L'Hermite-Baleriaux M, Turek FW, Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol. 2003 Mar; 284(3):R714-24. PMID: 12571075.
      Citations: 74     Fields:    Translation:Humans
    75. Leproult R, Colecchia EF, Berardi AM, Stickgold R, Kosslyn SM, Van Cauter E. Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated. Am J Physiol Regul Integr Comp Physiol. 2003 Feb; 284(2):R280-90. PMID: 12529281.
      Citations: 61     Fields:    Translation:HumansCTClinical Trials
    76. Spiegel K, Sheridan JF, Van Cauter E, Spiegel K, Sheridan JF, Van Cauter E. Effect of sleep deprivation on response to immunization. JAMA. 2002 Sep 25; 288(12):1471-2. PMID: 12243633.
      Citations: 143     Fields:    Translation:HumansPHPublic Health
    77. Caufriez A, Moreno-Reyes R, Leproult R, Vertongen F, Van Cauter E, Copinschi G. Immediate effects of an 8-h advance shift of the rest-activity cycle on 24-h profiles of cortisol. Am J Physiol Endocrinol Metab. 2002 May; 282(5):E1147-53. PMID: 11934681.
      Citations: 11     Fields:    Translation:Humans
    78. Cacioppo JT, Hawkley LC, Crawford LE, Ernst JM, Burleson MH, Kowalewski RB, Malarkey WB, Van Cauter E, Berntson GG. Loneliness and health: potential mechanisms. Psychosom Med. 2002 May-Jun; 64(3):407-17. PMID: 12021415.
      Citations: 261     Fields:    Translation:Humans
    79. Tasali E, Van Cauter E. Sleep-disordered breathing and the current epidemic of obesity: consequence or contributing factor? Am J Respir Crit Care Med. 2002 Mar 01; 165(5):562-3. PMID: 11874803.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    80. Van Cauter E, Leproult R, Plat L. Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men. JAMA. 2000 Aug 16; 284(7):861-8. PMID: 10938176.
      Citations: 174     Fields:    Translation:Humans
    81. Van Cauter E, Copinschi G. Interrelationships between growth hormone and sleep. Growth Horm IGF Res. 2000 Apr; 10 Suppl B:S57-62. PMID: 10984255.
      Citations: 16     Fields:    Translation:HumansAnimals
    82. Van Cauter E, Spiegel K. Sleep as a mediator of the relationship between socioeconomic status and health: a hypothesis. Ann N Y Acad Sci. 1999; 896:254-61. PMID: 10681902.
      Citations: 42     Fields:    Translation:Humans
    83. Van Cauter E, Plat L, Leproult R, Copinschi G. Alterations of circadian rhythmicity and sleep in aging: endocrine consequences. Horm Res. 1998; 49(3-4):147-52. PMID: 9550116.
      Citations: 23     Fields:    Translation:HumansAnimals
    84. Sturis J, Knudsen C, O'Meara NM, Thomsen JS, Mosekilde E, Van Cauter E, Polonsky KS. Phase-locking regions in a forced model of slow insulin and glucose oscillations. Chaos. 1995 Mar; 5(1):193-199. PMID: 12780173.
      Citations: 3     Fields:    
    85. Van Cauter EV, Polonsky KS, Blackman JD, Roland D, Sturis J, Byrne MM, Scheen AJ. Abnormal temporal patterns of glucose tolerance in obesity: relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity. J Clin Endocrinol Metab. 1994 Dec; 79(6):1797-805. PMID: 7989487.
      Citations: 13     Fields:    Translation:Humans
    86. Van Cauter EW, Virasoro E, Leclercq R, Copinschi G. Seasonal, circadian and episodic variations of human immunoreactive beta-MSH, ACTH and cortisol. Int J Pept Protein Res. 1981 Jan; 17(1):3-13. PMID: 6262256.
      Citations: 8     Fields:    Translation:Humans
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