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Tong-Chuan He to Signal Transduction

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This is a "connection" page, showing publications Tong-Chuan He has written about Signal Transduction.
Tong-Chuan He
Connection Strength
3.423
Signal Transduction
  1. Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914.
    View in: PubMed
    Score: 0.301
  2. Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98.
    View in: PubMed
    Score: 0.212
  3. Tetrandrine inhibits Wnt/ß-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol. 2011 Feb; 79(2):211-9.
    View in: PubMed
    Score: 0.171
  4. Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation. 2009 Nov; 78(4):195-204.
    View in: PubMed
    Score: 0.156
  5. BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med. 2009 Aug; 13(8B):2448-2464.
    View in: PubMed
    Score: 0.149
  6. Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest. 2007 Feb; 87(2):97-103.
    View in: PubMed
    Score: 0.132
  7. Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets. 2004 Dec; 4(8):653-71.
    View in: PubMed
    Score: 0.114
  8. Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies. Cancer Cell. 2024 Aug 12; 42(8):1336-1351.e9.
    View in: PubMed
    Score: 0.111
  9. Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem. 2003 Dec 15; 90(6):1149-65.
    View in: PubMed
    Score: 0.106
  10. Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Lett. 2003 Apr 25; 193(2):161-70.
    View in: PubMed
    Score: 0.102
  11. Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427.
    View in: PubMed
    Score: 0.090
  12. Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling. Stem Cells Dev. 2020 04 15; 29(8):498-510.
    View in: PubMed
    Score: 0.082
  13. Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2020 01; 24(2):1399-1412.
    View in: PubMed
    Score: 0.080
  14. Imiquimod Acts Synergistically with BMP9 through the Notch Pathway as an Osteoinductive Agent In Vitro. Plast Reconstr Surg. 2019 11; 144(5):1094-1103.
    View in: PubMed
    Score: 0.080
  15. A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies. Int J Mol Med. 2019 Nov; 44(5):1653-1666.
    View in: PubMed
    Score: 0.079
  16. BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Lab Invest. 2019 01; 99(1):58-71.
    View in: PubMed
    Score: 0.074
  17. Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cell Physiol Biochem. 2017; 41(5):1905-1923.
    View in: PubMed
    Score: 0.067
  18. Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid's anti-metastatic effect in 4T1 tumor bearing mice. Oncotarget. 2016 Nov 01; 7(44):71802-71816.
    View in: PubMed
    Score: 0.065
  19. Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2015 Jun; 35(6):1641-50.
    View in: PubMed
    Score: 0.058
  20. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets. 2015; 15(8):726-38.
    View in: PubMed
    Score: 0.057
  21. TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol. J Pharmacol Sci. 2015 Jan; 127(1):83-91.
    View in: PubMed
    Score: 0.057
  22. Signal transduction in the erythropoietin receptor system. Stem Cells. 1993 Sep; 11(5):381-92.
    View in: PubMed
    Score: 0.052
  23. Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013; 32(2):486-98.
    View in: PubMed
    Score: 0.052
  24. Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells. J Cell Mol Med. 2013 Sep; 17(9):1160-72.
    View in: PubMed
    Score: 0.052
  25. Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways. Oncol Rep. 2013 Jul; 30(1):292-8.
    View in: PubMed
    Score: 0.051
  26. Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res. 2012 Jul; 27(7):1566-75.
    View in: PubMed
    Score: 0.048
  27. Enhancement of canonical Wnt/ß-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One. 2011; 6(11):e27496.
    View in: PubMed
    Score: 0.046
  28. BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential. Curr Gene Ther. 2011 Jun; 11(3):229-40.
    View in: PubMed
    Score: 0.045
  29. The therapeutic potential of the Wnt signaling pathway in bone disorders. Curr Mol Pharmacol. 2011 Jan; 4(1):14-25.
    View in: PubMed
    Score: 0.043
  30. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol. 2011 Feb; 38(2):437-45.
    View in: PubMed
    Score: 0.043
  31. Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov; 29(10):1569-81.
    View in: PubMed
    Score: 0.040
  32. Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development. Development. 2009 Jun; 136(12):2081-9.
    View in: PubMed
    Score: 0.039
  33. Neurogenesis-related genes expression profiling of mouse fibroblastic stem cells induced by Wnt signaling. Neurol Res. 2009 Mar; 31(2):200-3.
    View in: PubMed
    Score: 0.038
  34. Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res. 2008 Sep; 466(9):2114-30.
    View in: PubMed
    Score: 0.036
  35. Regulation of osteogenic differentiation during skeletal development. Front Biosci. 2008 Jan 01; 13:2001-21.
    View in: PubMed
    Score: 0.035
  36. Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res. 2007 May; 25(5):665-77.
    View in: PubMed
    Score: 0.034
  37. CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol. 2006 Apr; 26(8):2955-64.
    View in: PubMed
    Score: 0.031
  38. Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Dec 31; 279(53):55958-68.
    View in: PubMed
    Score: 0.028
  39. Effect of antibiotic monensin on cell proliferation and IGF1R signaling pathway in human colorectal cancer cells. Ann Med. 2023 12; 55(1):954-964.
    View in: PubMed
    Score: 0.027
  40. Systematic Review of Nonsyndromic Craniosynostosis: Genomic Alterations and Impacted Signaling Pathways. Plast Reconstr Surg. 2024 02 01; 153(2):383e-396e.
    View in: PubMed
    Score: 0.025
  41. Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Aging (Albany NY). 2019 12 12; 11(23):11520-11540.
    View in: PubMed
    Score: 0.020
  42. ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia. Cancer Res. 2020 03 01; 80(5):988-998.
    View in: PubMed
    Score: 0.020
  43. The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation. FASEB J. 2019 02; 33(2):2132-2143.
    View in: PubMed
    Score: 0.019
  44. Identification of c-MYC as a target of the APC pathway. Science. 1998 Sep 04; 281(5382):1509-12.
    View in: PubMed
    Score: 0.018
  45. Whole-Proteome Analysis of Human Craniosynostotic Tissue Suggests a Link between Inflammatory Signaling and Osteoclast Activation in Human Cranial Suture Patency. Plast Reconstr Surg. 2018 02; 141(2):250e-260e.
    View in: PubMed
    Score: 0.018
  46. Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes. Oncotarget. 2017 May 30; 8(22):35890-35901.
    View in: PubMed
    Score: 0.017
  47. A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88.
    View in: PubMed
    Score: 0.016
  48. Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523.
    View in: PubMed
    Score: 0.015
  49. Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. Cell Physiol Biochem. 2015; 37(2):548-62.
    View in: PubMed
    Score: 0.014
  50. Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 Jan; 39:145-54.
    View in: PubMed
    Score: 0.014
  51. BMP9 regulates cross-talk between breast cancer cells and bone marrow-derived mesenchymal stem cells. Cell Oncol (Dordr). 2014 Oct; 37(5):363-75.
    View in: PubMed
    Score: 0.014
  52. Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. J Biol Chem. 1994 Aug 26; 269(34):21411-4.
    View in: PubMed
    Score: 0.014
  53. Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res. 2013 Nov; 31(11):1796-803.
    View in: PubMed
    Score: 0.013
  54. Paraptosis and NF-?B activation are associated with protopanaxadiol-induced cancer chemoprevention. BMC Complement Altern Med. 2013 Jan 03; 13:2.
    View in: PubMed
    Score: 0.012
  55. BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2013 Jan 15; 126(Pt 2):532-41.
    View in: PubMed
    Score: 0.012
  56. LIGHT delivery to tumors by mesenchymal stem cells mobilizes an effective antitumor immune response. Cancer Res. 2012 Jun 15; 72(12):2980-9.
    View in: PubMed
    Score: 0.012
  57. All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. Int J Oncol. 2012 Jul; 41(1):153-60.
    View in: PubMed
    Score: 0.012
  58. Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett. 2011 Feb 28; 301(2):185-92.
    View in: PubMed
    Score: 0.011
  59. Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res. 2010 Nov; 25(11):2447-59.
    View in: PubMed
    Score: 0.011
  60. The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histol Histopathol. 2010 06; 25(6):795-806.
    View in: PubMed
    Score: 0.010
  61. Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells. Dev Growth Differ. 2010 Jun; 52(5):419-31.
    View in: PubMed
    Score: 0.010
  62. Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2005 Jul; 289(1):G129-37.
    View in: PubMed
    Score: 0.007
  63. CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. Oncogene. 1999 Sep 02; 18(35):5010-4.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.