Tobin Sosnick to Protein Conformation
This is a "connection" page, showing publications Tobin Sosnick has written about Protein Conformation.
Connection Strength
3.032
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Metal binding kinetics of bi-histidine sites used in psi analysis: evidence of high-energy protein folding intermediates. Biochemistry. 2009 Apr 07; 48(13):2950-9.
Score: 0.243
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Characterizing protein folding transition States using Psi-analysis. Methods Mol Biol. 2007; 350:83-104.
Score: 0.208
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Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well? Annu Rev Biophys. 2025 05; 54(1):17-34.
Score: 0.180
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Distinguishing foldable proteins from nonfolders: when and how do they differ? Proteins. 2002 Oct 01; 49(1):15-23.
Score: 0.155
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Lipid bilayer induces contraction of the denatured state ensemble of a helical-bundle membrane protein. Proc Natl Acad Sci U S A. 2022 01 04; 119(1).
Score: 0.147
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Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence. J Chem Theory Comput. 2022 Jan 11; 18(1):550-561.
Score: 0.147
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Folding and misfolding of potassium channel monomers during assembly and tetramerization. Proc Natl Acad Sci U S A. 2021 08 24; 118(34).
Score: 0.143
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Water as a Good Solvent for Unfolded Proteins: Folding and Collapse are Fundamentally Different. J Mol Biol. 2020 04 17; 432(9):2882-2889.
Score: 0.129
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Commonly used FRET fluorophores promote collapse of an otherwise disordered protein. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):8889-8894.
Score: 0.122
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Trajectory-based training enables protein simulations with accurate folding and Boltzmann ensembles in cpu-hours. PLoS Comput Biol. 2018 12; 14(12):e1006578.
Score: 0.119
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Accurate calculation of side chain packing and free energy with applications to protein molecular dynamics. PLoS Comput Biol. 2018 12; 14(12):e1006342.
Score: 0.119
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Response to Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water". Science. 2018 08 31; 361(6405).
Score: 0.117
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Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4747-52.
Score: 0.099
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The role of helix formation in the folding of a fully alpha-helical coiled coil. Proteins. 1996 Apr; 24(4):427-32.
Score: 0.099
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Factors that control the chemistry of the LOV domain photocycle. PLoS One. 2014; 9(1):e87074.
Score: 0.085
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Folding of a large protein at high structural resolution. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18898-903.
Score: 0.083
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A "Link-Psi" strategy using crosslinking indicates that the folding transition state of ubiquitin is not very malleable. Protein Sci. 2012 Jun; 21(6):819-27.
Score: 0.075
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Modeling large regions in proteins: applications to loops, termini, and folding. Protein Sci. 2012 Jan; 21(1):107-21.
Score: 0.073
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A probabilistic and continuous model of protein conformational space for template-free modeling. J Comput Biol. 2010 Jun; 17(6):783-98.
Score: 0.066
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Protein structure prediction enhanced with evolutionary diversity: SPEED. Protein Sci. 2010 Mar; 19(3):520-34.
Score: 0.065
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Folding of a universal ribozyme: the ribonuclease P RNA. Q Rev Biophys. 2007 May; 40(2):113-61.
Score: 0.055
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Investigations into sequence and conformational dependence of backbone entropy, inter-basin dynamics and the Flory isolated-pair hypothesis for peptides. J Mol Biol. 2003 Aug 15; 331(3):693-711.
Score: 0.041
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Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding. J Mol Biol. 2002 Nov 22; 324(2):359-71.
Score: 0.039
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Dynamics of hydrogen bond desolvation in protein folding. J Mol Biol. 2002 Aug 23; 321(4):659-75.
Score: 0.038
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Challenges and Advantages of Accounting for Backbone Flexibility in Prediction of Protein-Protein Complexes. J Chem Theory Comput. 2022 Mar 08; 18(3):2016-2032.
Score: 0.037
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Engineered metal binding sites map the heterogeneous folding landscape of a coiled coil. Nat Struct Biol. 2001 Dec; 8(12):1042-7.
Score: 0.037
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The thermodynamic origin of the stability of a thermophilic ribozyme. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4355-60.
Score: 0.035
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Properties of protein unfolded states suggest broad selection for expanded conformational ensembles. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23356-23364.
Score: 0.033
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Structural basis for adhesion G protein-coupled receptor Gpr126 function. Nat Commun. 2020 01 10; 11(1):194.
Score: 0.032
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Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil folding. Biochemistry. 1998 Oct 13; 37(41):14613-22.
Score: 0.029
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Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends. Biochemistry. 1997 May 13; 36(19):5806-16.
Score: 0.027
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Protein minimization: downsizing through mutation. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12):5680-1.
Score: 0.025
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Random coil negative control reproduces the discrepancy between scattering and FRET measurements of denatured protein dimensions. Proc Natl Acad Sci U S A. 2015 May 26; 112(21):6631-6.
Score: 0.023
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Denatured states of ribonuclease A have compact dimensions and residual secondary structure. Biochemistry. 1992 Sep 08; 31(35):8329-35.
Score: 0.019
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Small-angle X-ray scattering and single-molecule FRET spectroscopy produce highly divergent views of the low-denaturant unfolded state. J Mol Biol. 2012 May 04; 418(3-4):226-36.
Score: 0.018
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Outcome of a workshop on applications of protein models in biomedical research. Structure. 2009 Feb 13; 17(2):151-9.
Score: 0.015
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Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library. Biochemistry. 2005 Jul 19; 44(28):9691-702.
Score: 0.012
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Single-molecule studies highlight conformational heterogeneity in the early folding steps of a large ribozyme. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):534-9.
Score: 0.011
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Large-scale context in protein folding: villin headpiece. Biochemistry. 2003 Jan 28; 42(3):664-71.
Score: 0.010
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Mechanisms and uses of hydrogen exchange. Curr Opin Struct Biol. 1996 Feb; 6(1):18-23.
Score: 0.006
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Protein folding intermediates: native-state hydrogen exchange. Science. 1995 Jul 14; 269(5221):192-7.
Score: 0.006
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Structures of fd gene 5 protein.nucleic acid complexes: a combined solution scattering and electron microscopy study. J Mol Biol. 1995 Jun 09; 249(3):576-94.
Score: 0.006
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Expression in Escherichia coli and characterization of the heat-stable inhibitor of the cAMP-dependent protein kinase. J Biol Chem. 1991 Jun 15; 266(17):10906-11.
Score: 0.004