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Shasha Wu

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentNeurology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Wu's research focuses on the investigation of EEG biomarkers for the epileptogenic tissue, such as infra slowing activity and High-Frequency Oscillations using intracranial EEG recordings. The goal of the research is to help in delineating the epileptic brain tissue for epilepsy surgery and to improve the surgical outcome.


    Collapse Biography 
    Collapse education and training
    University Hospitals Case Medical Center, Cleveland, OH06/2012Clinical Fellowship in Clinical Neurophysiology and Epilepsy
    University of Vermont, Burlington, VT06/2010Neurology Residency
    AtlantiCare Regional Medical Center, Atlantic City, NJ06/2007Medical Intership
    University of Pittsburgh, Pittsburgh, PA06/2006Research Fellow
    Peking University, Beijing, ChinaPhD06/2000Molecular Biology
    Baotou Medical College, Inner Mongolia, ChinaMD06/1994Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Abumurad S, Issa NP, Wu S, Rose S, Taylan Esengul Y, Nordli D, Warnke PC, Tao JX. Laser interstitial thermal therapy for NPRL3-related epilepsy with multiple seizure foci: A case report. Epilepsy Behav Rep. 2021; 16:100459. PMID: 34235417.
      View in: PubMed
    2. Wu S, Issa NP, Lacy M, Satzer D, Rose SL, Yang CW, Collins JM, Liu X, Sun T, Towle VL, Nordli DR, Warnke PC, Tao JX. Surgical Outcomes and EEG Prognostic Factors After Stereotactic Laser Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy. Front Neurol. 2021; 12:654668. PMID: 34079512.
      View in: PubMed
    3. Lee S, Wu S, Tao JX, Rose S, Warnke PC, Issa NP, van Drongelen W. Manifestation of Hippocampal Interictal Discharges on Clinical Scalp EEG Recordings. J Clin Neurophysiol. 2021 May 14. PMID: 34010227.
      View in: PubMed
    4. Del Brutto OH, Mera RM, Wu S, Recalde BY, Issa NP. Epilepsy, interictal EEG abnormalities and hippocampal atrophy in patients with calcified neurocysticercosis: a population study in an endemic milieu. Epileptic Disord. 2021 Apr 01; 23(2):357-365. PMID: 33926860.
      View in: PubMed
    5. Santos de Lima F, Klein S, El Ammar F, Wu S, Rose S, Tao JX, Issa NP. Rapid development of seizures and PRES in a COVID-19 patient. Epilepsy Behav Rep. 2021; 15:100436. PMID: 33688630.
      View in: PubMed
    6. Del Brutto OH, Wu S, Mera RM, Costa AF, Recalde BY, Issa NP. Cognitive decline among individuals with history of mild symptomatic SARS-CoV-2 infection: A longitudinal prospective study nested to a population cohort. Eur J Neurol. 2021 Feb 11. PMID: 33576150.
      View in: PubMed
    7. Santos de Lima F, Issa N, Seibert K, Davis J, Wlodarski R, Klein S, El Ammar F, Wu S, Rose S, Warnke P, Tao J. Epileptiform activity and seizures in patients with COVID-19. J Neurol Neurosurg Psychiatry. 2021 05; 92(5):565-566. PMID: 33158913.
      View in: PubMed
    8. Zheng W, Minama Reddy GK, Dai F, Chandramani A, Brang D, Hunter S, Kohrman MH, Rose S, Rossi M, Tao J, Wu S, Byrne R, Frim DM, Warnke P, Towle VL. Chasing language through the brain: Successive parallel networks. Clin Neurophysiol. 2021 01; 132(1):80-93. PMID: 33360179.
      View in: PubMed
    9. Chen Z, Issa NP, Wu S, Liu X, Sun T, Bodnya J, Rose S, Tao JX. The clinical significance of small sharp spikes: A retrospective study of 909 patients in epilepsy monitoring unit. Epilepsy Res. 2020 12; 168:106477. PMID: 33096313.
      View in: PubMed
    10. Sun T, Liu X, Issa NP, Rose S, Wu S, Wang Q, Martinez R, Towle VL, Jr DRN, Warnke P, Tao JX. RTTBD-like activity in association with hippocampal ictal discharges in patients with temporal lobe epilepsy. Epileptic Disord. 2020 Aug 01; 22(4):462-472. PMID: 32763870.
      View in: PubMed
    11. Arabkheradmand G, Zhou G, Noto T, Yang Q, Schuele SU, Parvizi J, Gottfried JA, Wu S, Rosenow JM, Koubeissi MZ, Lane G, Zelano C. Anticipation-induced delta phase reset improves human olfactory perception. PLoS Biol. 2020 05; 18(5):e3000724. PMID: 32453719.
      View in: PubMed
    12. Tao JX, Satzer D, Issa NP, Collins J, Wu S, Rose S, Henry J, Santos de Lima F, Nordli D, Warnke PC. Stereotactic laser anterior corpus callosotomy for Lennox-Gastaut syndrome. Epilepsia. 2020 06; 61(6):1190-1200. PMID: 32401350.
      View in: PubMed
    13. Satzer D, Tao JX, Issa NP, Chen Z, Wu S, Rose S, Collins J, Awad IA, Warnke PC. Stereotactic laser interstitial thermal therapy for epilepsy associated with solitary and multiple cerebral cavernous malformations. Neurosurg Focus. 2020 04 01; 48(4):E12. PMID: 32234994.
      View in: PubMed
    14. Issa NP, Wu S, Rose S, Tao JX. Prone position: An underrecognized and preventable risk for SUDEP. Epilepsy Behav. 2020 03; 104(Pt A):106918. PMID: 32058301.
      View in: PubMed
    15. Rose S, Issa NP, Wu S, Liu X, Tao JX. Reader response: Postconvulsive central apnea as a biomarker for sudden unexpected death in epilepsy (SUDEP). Neurology. 2019 12 03; 93(23):1020-1021. PMID: 31792108.
      View in: PubMed
    16. Tao JX, Issa NP, Wu S, Rose S, Collins J, Warnke PC. Interstitial Stereotactic Laser Anterior Corpus Callosotomy: A Report of 2 Cases with Operative Technique and Effectiveness. Neurosurgery. 2019 09 01; 85(3):E569-E574. PMID: 29982584.
      View in: PubMed
    17. Liu X, Wu S, Daif A, Sun T, Chauhan V, Issa NP, Rose S, Tao JX. Clinical implications of scalp ictal EEG pattern in patients with temporal lobe epilepsy. Clin Neurophysiol. 2019 09; 130(9):1604-1610. PMID: 31319289.
      View in: PubMed
    18. Lee S, Issa NP, Rose S, Tao JX, Warnke PC, Towle VL, van Drongelen W, Wu S. DC shifts, high frequency oscillations, ripples and fast ripples in relation to the seizure onset zone. Seizure. 2020 Apr; 77:52-58. PMID: 31101405.
      View in: PubMed
    19. Plass J, Ahn E, Towle VL, Stacey WC, Wasade VS, Tao J, Wu S, Issa NP, Brang D. Joint Encoding of Auditory Timing and Location in Visual Cortex. J Cogn Neurosci. 2019 07; 31(7):1002-1017. PMID: 30912728.
      View in: PubMed
    20. Liu X, Issa NP, Rose S, Wu S, Sun T, Towle LV, Warnke PC, Tao JX. The first-hour-of-the-day sleep EEG reliably identifies interictal epileptiform discharges during long-term video-EEG monitoring. Seizure. 2018 Dec; 63:48-51. PMID: 30399461.
      View in: PubMed
    21. Issa NP, Lee S, Wu S, Rose S, Towle VL, Warnke PC, van Drongelen W, Tao JX. Reply to "which small sharp spikes are benign epileptiform transients of sleep?" Clin Neurophysiol. 2018 11; 129(11):2495-2496. PMID: 30268708.
      View in: PubMed
    22. Bruzzone MJ, Issa N, Rose S, Warnke P, Towle VL, Tao JX, Wu S. Insights Into the Therapeutic Effect of Responsive Neurostimulation Assessed With Scalp EEG Recording: A Case Report. J Clin Neurophysiol. 2018 Sep; 35(5):438-441. PMID: 29023305.
      View in: PubMed
    23. Issa NP, Wu S, Rose S, Towle VL, Warnke PC, Tao JX. Small sharp spikes as EEG markers of mesiotemporal lobe epilepsy. Clin Neurophysiol. 2018 09; 129(9):1796-1803. PMID: 30005212.
      View in: PubMed
    24. Daif A, Lukas RV, Issa NP, Javed A, VanHaerents S, Reder AT, Tao JX, Warnke P, Rose S, Towle VL, Wu S. Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy. Epilepsy Behav. 2018 03; 80:331-336. PMID: 29433947.
      View in: PubMed
    25. Tao JX, Wu S, Lacy M, Rose S, Issa NP, Yang CW, Dorociak KE, Bruzzone M, Kim J, Daif A, Choi J, Towle VL, Warnke PC. Stereotactic EEG-guided laser interstitial thermal therapy for mesial temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2018 05; 89(5):542-548. PMID: 29183959.
      View in: PubMed
    26. Ali A, Wu S, Issa NP, Rose S, Towle VL, Warnke P, Tao JX. Association of sleep with sudden unexpected death in epilepsy. Epilepsy Behav. 2017 11; 76:1-6. PMID: 28917499.
      View in: PubMed
    27. Jiang H, Schuele S, Rosenow J, Zelano C, Parvizi J, Tao JX, Wu S, Gottfried JA. Theta Oscillations Rapidly Convey Odor-Specific Content in Human Piriform Cortex. Neuron. 2017 Apr 05; 94(1):207-219.e4. PMID: 28384472.
      View in: PubMed
    28. Tao JX, Issa N, Collins JW, Wu S, Rose S, Warnke P. Homonymous hemianopsia after MR-guided stereotactic laser amygdalohippocampectomy. Epilepsy Behav. 2017 01; 66:140-141. PMID: 27993511.
      View in: PubMed
    29. Serafini A, Issa NP, Rose S, Wu S, Warnke P, Tao JX. TIRDA Originating From Lateral Temporal Cortex in a Patient With mTLE Is Not Related to Hippocampal Activity. J Clin Neurophysiol. 2016 Dec; 33(6):e34-e38. PMID: 27753735.
      View in: PubMed
    30. Wang S, Graf S, Xu J, Issa NP, Ali A, Rose S, Wu S, Jacobsen J, Warnke P, Tao JX. The incidence of peri-ictal prone position in patients with generalized convulsive seizures. Epilepsy Behav. 2016 08; 61:158-161. PMID: 27351726.
      View in: PubMed
    31. Serafini A, Lukas RV, VanHaerents S, Warnke P, Tao JX, Rose S, Wu S. Paraneoplastic epilepsy. Epilepsy Behav. 2016 08; 61:51-58. PMID: 27304613.
      View in: PubMed
    32. Wu S, Issa NP, Rose SL, Ali A, Tao JX. Impact of periictal nurse interventions on postictal generalized EEG suppression in generalized convulsive seizures. Epilepsy Behav. 2016 05; 58:22-5. PMID: 26994879.
      View in: PubMed
    33. Wu S, Tao XJ, Issa N, Rose S, Warnke P. MR-guided laser interstitial thermal therapy for the treatment of medically refractory epilepsy. Int J Neurol Neurother. 2016; (3):42.
    34. Tao J, Liebenthal J, Wu S, Rose S, Ebersole JS. Author response:. Neurology. 2015 Sep 29; 85(13):1185-6. PMID: 26688873.
      View in: PubMed
    35. Rose S, Wu S, Jiang A, Kim J, Tao JX. Neurogenic pulmonary edema: An etiological factor for SUDEP? Epilepsy Behav. 2015 Nov; 52(Pt A):76-7. PMID: 26409134.
      View in: PubMed
    36. Brang D, Towle VL, Suzuki S, Hillyard SA, Di Tusa S, Dai Z, Tao J, Wu S, Grabowecky M. Peripheral sounds rapidly activate visual cortex: evidence from electrocorticography. J Neurophysiol. 2015 Nov; 114(5):3023-8. PMID: 26334017.
      View in: PubMed
    37. Tao JX, Sandra R, Wu S, Ebersole JS. Should the "Back to Sleep" campaign be advocated for SUDEP prevention? Epilepsy Behav. 2015 Apr; 45:79-80. PMID: 25875185.
      View in: PubMed
    38. Liebenthal JA, Wu S, Rose S, Ebersole JS, Tao JX. Association of prone position with sudden unexpected death in epilepsy. Neurology. 2015 Feb 17; 84(7):703-9. PMID: 25609764.
      View in: PubMed
    39. Wu S, Kunhi Veedu HP, Lhatoo SD, Koubeissi MZ, Miller JP, L├╝ders HO. Role of ictal baseline shifts and ictal high-frequency oscillations in stereo-electroencephalography analysis of mesial temporal lobe seizures. Epilepsia. 2014 May; 55(5):690-8. PMID: 24725106.
      View in: PubMed
    40. Lee A, Wu S, Zhou X, Liebenthal J, Rose S, Tao JX. Periictal autonomic dysfunction and generalized postictal EEG suppression in convulsive seizures arising from sleep and wakefulness. Epilepsy Behav. 2013 Sep; 28(3):439-43. PMID: 23891764.
      View in: PubMed
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