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Jubao Duan

TitleProfessor, Part-Time
InstitutionUniversity of Chicago
DepartmentPsychiatry & Behav. Neurosci
AddressChicago IL 60637
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    Collapse overview
    Jubao Duan, PhD

    Charles R. Walgreen Research Chair
    Director, Stem Cell & Functional Genomics in Psychiatry
    Co-Director, Center for Psychiatric Genetics
    NorthShore University HealthSystem Research Institute
    Professor, Department of Psychiatry and Behavioral Neuroscience

    Contact Information
    1001 University Place, Evanston, IL 60201
    224.364.7564
    224.364.7570 fax
    jduan@uchicago.edu; jduan@northshore.org

    Research Interests

    Molecular basis of schizophrenia and other neuropsychiatric and neurological disorders; Functional genetics and genomics; Disease modeling in human induced pluripotent stem cells (hiPSC)-derived neurons and brain organoids; Genome editing; Gene expression and regulation.

    Professional Services

    *Editorial Board Member: Complex Psychiatry; Frontiers in Neurogenomics; Scientific Reports
    *Ad hoc grant reviewer for MRC (Medical Research Council) of UK, Research Grant Council (RGC) of Hong Kong and other international agencies
    *2020 US VA Mental Hlth & Behav Sciences-A (MHBA) study section meeting
    *Ad hoc member of NIH study sections: IFCN-Z(57) and BDCN-W(06)M (2017); MDCN-P (57) (2016-2019); NINDS ZNS1 SRB-A (24) Special Emphasis Panel (LBD Center Without Walls (CWOW)) and IFCN-S (55) (2020); ZRG1 BCMB-A (51) R (Transformative R01 Program) (2020); NINDS ZNS1 SRB-S(03) U54 and GHD (2021)

    Collapse Biography 
    Collapse awards and honors
    2019 - 2020Provost's Global Faculty Award, University of Chicago
    2017Excellence in Research Award, NorthShore University Healthsystem, Northshore University Healthsystem
    2016Special President’s Award,NorthShore University Healthsystem, NorthShore University Healthsystem
    2015Excellence in Research Award,Northshore University Healthsystem, Northshore University Healthsystem
    2011NorthShore University HealthSystem Pilot Grant Award, NorthShore University HealthSystem
    2006NARSAD Elizabeth Elser Doolittle Investigator , National Alliance for Research of Schizophrenia and Depression
    2005NARSAD Young Investigator Award, National Alliance for Research of Schizophrenia and Depression
    2004Evanston Northwestern Healthcare Research Career Development Award, Evanston Northwestern Healthcare
    2001NARSAD Young Investigator Award, National Alliance for Research of Schizophrenia and Depression

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang H, Peyton L, McCarroll A, de León Guerrerro SD, Zhang S, Gowda P, Sirkin D, El Achwah M, Duhe A, Wood WG, Jamison B, Tracy G, Pollak R, Hart RP, Pato CN, Mulle JG, Sanders AR, Pang ZP, Duan J. Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC. bioRxiv. 2024 Mar 19. PMID: 38562852; PMCID: PMC10983959.
      Citations:    
    2. Zhao X, Zhang S, Sanders AR, Duan J. Brain Lipids and Lipid Droplet Dysregulation in Alzheimer's Disease and Neuropsychiatric Disorders. Complex Psychiatry. 2023 Jan-Dec; 9(1-4):154-171. PMID: 38058955; PMCID: PMC10697751.
      Citations:    
    3. Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE, Sanders AR, Pang ZP, He X, Penzes P, Duan J. Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons. Cell Genom. 2023 Sep 13; 3(9):100399. PMID: 37719141; PMCID: PMC10504676.
      Citations: 4     
    4. Duan J. Human stem cell modeling of neuropsychiatric disorders: from polygenicity to convergence. Med Rev (2021). 2023 Aug; 3(4):347-350. PMID: 38235404; PMCID: PMC10790208.
      Citations:    
    5. Aksenov DP, Gascoigne DA, Duan J, Drobyshevsky A. Function and development of interneurons involved in brain tissue oxygen regulation. Front Mol Neurosci. 2022; 15:1069496. PMID: 36504684; PMCID: PMC9729339.
      Citations:    
    6. Parnell E, Culotta L, Forrest MP, Jalloul HA, Eckman BL, Loizzo DD, Horan KKE, Dos Santos M, Piguel NH, Tai DJC, Zhang H, Gertler TS, Simkin D, Sanders AR, Talkowski ME, Gejman PV, Kiskinis E, Duan J, Penzes P. Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons. Biol Psychiatry. 2023 07 15; 94(2):153-163. PMID: 36581494; PMCID: PMC10166768.
      Citations: 5     Fields:    Translation:HumansCells
    7. Zhang S, Sanders AR, Duan J. Modeling PTSD neuronal stress responses in a dish. Nat Neurosci. 2022 Nov; 25(11):1402-1404. PMID: 36266472; PMCID: PMC9721095.
      Citations: 3     Fields:    Translation:HumansCells
    8. Kozlova A, Zhang S, Kotlar AV, Jamison B, Zhang H, Shi S, Forrest MP, McDaid J, Cutler DJ, Epstein MP, Zwick ME, Pang ZP, Sanders AR, Warren ST, Gejman PV, Mulle JG, Duan J. Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons. Am J Hum Genet. 2022 08 04; 109(8):1500-1519. PMID: 35931052; PMCID: PMC9388388.
      Citations: 5     Fields:    Translation:HumansCells
    9. Yue W, Huang H, Duan J. Potential diagnostic biomarkers for schizophrenia. Med Rev (Berl). 2022 Aug; 2(4):385-416. PMID: 37724326; PMCID: PMC10388817.
      Citations: 1     
    10. Lai B, Qian S, Zhang H, Zhang S, Kozlova A, Duan J, Xu J, He X. Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning. PLoS Comput Biol. 2022 05; 18(5):e1010011. PMID: 35576194; PMCID: PMC9135341.
      Citations: 4     Fields:    
    11. Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia. Mol Neurodegener. 2022 05 07; 17(1):33. PMID: 35526014; PMCID: PMC9077874.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    12. Muhtaseb AW, Duan J. Modeling common and rare genetic risk factors of neuropsychiatric disorders in human induced pluripotent stem cells. Schizophr Res. 2022 Apr 19. PMID: 35459617; PMCID: PMC9735430.
      Citations: 4     Fields:    
    13. Qi T, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Als TD, Amin F, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Belliveau RA, Benyamin B, Bergen SE, Blasi G, Bonassi S, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Cheng W, Cheung EFC, Chong SA, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Genovese G, Gershon ES, Giegling I, Goldstein JI, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gur RE, Gur RC, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kubo M, Kucinskas V, Kucinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Molden E, Molina E, Mondelli V, Morley CP, Murphy KC, Myin-Germeys I, Nestadt G, Nikitina-Zake L, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Pantelis C, Papadimitriou GN, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Rutten BPF, Salomaa V, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Slominsky P, So HC, Sobell JL, Stain HJ, Steen NE, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Takahashi A, Terao C, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbasoglu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S, Indonesia Schizophrenia Consortium, PsychENCODE, Psychosis Endophenotypes International Consortium, SynGO Consortium, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Escott-Price V, Fanous AH, Gareeva A, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stefansson K, Tsuang MT, et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 04; 604(7906):502-508. PMID: 35396580; PMCID: PMC9392466.
      Citations: 460     Fields:    Translation:Humans
    14. Yang F, Gleason KJ, Wang J, Duan J, He X, Pierce BL, Chen LS. CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression. Bioinformatics. 2021 Sep 09; 37(17):2513-2520. PMID: 33647928; PMCID: PMC8428610.
      Citations: 1     Fields:    
    15. Yao Y, Guo W, Zhang S, Yu H, Yan H, Zhang H, Sanders AR, Yue W, Duan J. Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia. iScience. 2021 Jul 23; 24(7):102785. PMID: 34308291; PMCID: PMC8283158.
      Citations: 10     
    16. Doostparast Torshizi A, Duan J, Wang K. A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders. NAR Genom Bioinform. 2021 Jun; 3(2):lqab056. PMID: 34169279; PMCID: PMC8219045.
      Citations: 3     
    17. Kozlova A, Butler RR, Zhang S, Ujas T, Zhang H, Steidl S, Sanders AR, Pang ZP, Vezina P, Duan J. Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes. Neuropsychopharmacology. 2021 09; 46(10):1746-1756. PMID: 34007041; PMCID: PMC8358005.
      Citations: 2     Fields:    Translation:HumansAnimals
    18. Dobrindt K, Zhang H, Das D, Abdollahi S, Prorok T, Ghosh S, Weintraub S, Genovese G, Powell SK, Lund A, Akbarian S, Eggan K, McCarroll S, Duan J, Avramopoulos D, Brennand KJ. Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia. Complex Psychiatry. 2021 Feb; 6(3-4):68-82. PMID: 34883504; PMCID: PMC7923934.
      Citations: 14     
    19. Torshizi AD, Duan J, Wang K. Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes. Patterns (N Y). 2020 Sep 11; 1(6). PMID: 32984858; PMCID: PMC7518509.
      Citations: 3     
    20. Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. Science. 2020 07 31; 369(6503):561-565. PMID: 32732423; PMCID: PMC7773145.
      Citations: 47     Fields:    Translation:HumansCells
    21. Barretto N, Zhang H, Powell SK, Fernando MB, Zhang S, Flaherty EK, Ho SM, Slesinger PA, Duan J, Brennand KJ. ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs. J Neurosci Methods. 2020 Feb 14; 334:108548. PMID: 32065989; PMCID: PMC7426253.
      Citations: 20     Fields:    
    22. Duan J, Sanders AR, Gejman PV. From Schizophrenia Genetics to Disease Biology: Harnessing New Concepts and Technologies. J Psychiatr Brain Sci. 2019; 4. PMID: 31555746; PMCID: PMC6760308.
      Citations: 4     
    23. Doostparast Torshizi A, Armoskus C, Zhang H, Forrest MP, Zhang S, Souaiaia T, Evgrafov OV, Knowles JA, Duan J, Wang K. Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia. Sci Adv. 2019 09; 5(9):eaau4139. PMID: 31535015; PMCID: PMC6739105.
      Citations: 36     Fields:    Translation:HumansCells
    24. Butler Iii RR, Kozlova A, Zhang H, Zhang S, Streit M, Sanders AR, Laudanski K, Pang ZP, Gejman PV, Duan J. The Genetic Relevance of Human Induced Pluripotent Stem Cell-Derived Microglia to Alzheimer's Disease and Major Neuropsychiatric Disorders. Mol Neuropsychiatry. 2020 Apr; 5(Suppl 1):85-96. PMID: 32399472; PMCID: PMC7206606.
      Citations: 7     
    25. Kos MZ, Duan J, Sanders AR, Blondell L, Drigalenko EI, Carless MA, Gejman PV, MGS, Göring HHH. Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. Transl Psychiatry. 2018 12 13; 8(1):278. PMID: 30546022; PMCID: PMC6293320.
      Citations: 5     Fields:    Translation:HumansCells
    26. Duan J, Sanders AR, Moy W, Freda J, Drigalenko EI, Kos M, He D, Gejman PV, MGS, Göring HHH. Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model. Transl Psychiatry. 2018 08 16; 8(1):158. PMID: 30115913; PMCID: PMC6095865.
      Citations: 11     Fields:    Translation:HumansCells
    27. Doostparast Torshizi A, Duan J, Wang K. Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders. BMC Res Notes. 2018 Jul 17; 11(1):489. PMID: 30016992; PMCID: PMC6050725.
      Citations: 4     Fields:    Translation:HumansCells
    28. Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Owen MJ, Mead S, Passmore P, Morgan K, Rossor M, Lupton MK, Hoffmann P, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Wedenoja J, Buring JE, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Martin NG, Montgomery GW, Kurki MI, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono RJ, Catarino CB, De Jonghe P, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gibbs R, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Markus H, Kourkoulis C, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Ramos-Quiroga JA, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Waldman I, Wilmot B, Molly N, Crosbie J, Schachar R, Loo SK, McGough JJ, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Bolton P, Cantor R, Dawson G, De Rubeis S, Green A, Klauck SM, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Maaser A, Fischer SB, Fullerton JM, Mayoral F, Schofield PR, Cichon S, Degenhardt F, Schumacher J, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Ophoff R, Pato C, Anjorin A, et al. Analysis of shared heritability in common disorders of the brain. Science. 2018 06 22; 360(6395). PMID: 29930110; PMCID: PMC6097237.
      Citations: 685     Fields:    Translation:Humans
    29. Zhang S, Moy W, Zhang H, Leites C, McGowan H, Shi J, Sanders AR, Pang ZP, Gejman PV, Duan J. Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model. Stem Cell Res. 2018 05; 29:88-98. PMID: 29631039; PMCID: PMC6025752.
      Citations: 12     Fields:    Translation:HumansCells
    30. Sanders AR, Beecham GW, Guo S, Dawood K, Rieger G, Badner JA, Gershon ES, Krishnappa RS, Kolundzija AB, Duan J, MGS Collaboration, Gejman PV, Bailey JM, Martin ER. Genome-Wide Association Study of Male Sexual Orientation. Sci Rep. 2017 12 07; 7(1):16950. PMID: 29217827; PMCID: PMC5721098.
      Citations: 18     Fields:    Translation:HumansCells
    31. Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017 09 07; 21(3):305-318.e8. PMID: 28803920; PMCID: PMC5591074.
      Citations: 64     Fields:    Translation:HumansCells
    32. Stueve TR, Li WQ, Shi J, Marconett CN, Zhang T, Yang C, Mullen D, Yan C, Wheeler W, Hua X, Zhou B, Borok Z, Caporaso NE, Pesatori AC, Duan J, Laird-Offringa IA, Landi MT. Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers. Hum Mol Genet. 2017 08 01; 26(15):3014-3027. PMID: 28854564; PMCID: PMC5886283.
      Citations: 55     Fields:    Translation:HumansCells
    33. Shi J, Park JH, Duan J, Berndt ST, Moy W, Yu K, Song L, Wheeler W, Hua X, Silverman D, Garcia-Closas M, Hsiung CA, Figueroa JD, Cortessis VK, Karagas MR, Vineis P, Chang IS, Lin D, Zhou B, Seow A, Matsuo K, Hong YC, Caporaso NE, Wolpin B, Jacobs E, Petersen GM, Klein AP, Li D, Risch H, Sanders AR, Hsu L, Schoen RE, Brenner H, MGS (Molecular Genetics of Schizophrenia) GWAS Consortium, GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium), GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium, PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortiu, PanScan Consortium, GAME-ON/ELLIPSE Consortium, Stolzenberg-Solomon R, Gejman P, Lan Q, Rothman N, Amundadottir LT, Landi MT, Levinson DF, Chanock SJ, Chatterjee N, Malats N. Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016 Dec; 12(12):e1006493. PMID: 28036406; PMCID: PMC5201242.
      Citations: 57     Fields:    Translation:Humans
    34. Yu W, Kim HK, Rauch S, Schneewind O, Missiakas D. Pathogenic conversion of coagulase-negative staphylococci. Microbes Infect. 2017 02; 19(2):101-109. PMID: 28012900; PMCID: PMC5274588.
      Citations: 11     Fields:    Translation:AnimalsCells
    35. Anderson M, Ohr RJ, Aly KA, Nocadello S, Kim HK, Schneewind CE, Schneewind O, Missiakas D. EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection. J Bacteriol. 2017 01 01; 199(1). PMID: 27795322; PMCID: PMC5165088.
      Citations: 19     Fields:    Translation:AnimalsCells
    36. Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, Brodie SA, Palleschi A, Alloisio M, Pariscenti G, Jones K, Zhou W, Bouk AJ, Boland J, Hicks B, Risch A, Bennett H, Luke BT, Song L, Duan J, Liu P, Kohno T, Chen Q, Meerzaman D, Marconett C, Laird-Offringa I, Mills I, Caporaso NE, Gail MH, Pesatori AC, Consonni D, Bertazzi PA, Chanock SJ, Landi MT. Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. PLoS Med. 2016 Dec; 13(12):e1002162. PMID: 27923066; PMCID: PMC5140047.
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    37. Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato MT, Paunio T, Psychosis Endophenotypes International Consortium, Perkins DO, Pers TH, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J, CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, Crespo-Facorro B, Eriksson J, Giusti-Rodríguez P, Godard S, Kähler AK, Kahn RS, Lönnqvist J, Mallet J, Müller-Myhsok B, Nordin A, Pietiläinen O, Söderman E, Adolfsson R, Esko T, Jönsson EG, Nöthen MM. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017 01; 49(1):27-35. PMID: 27869829; PMCID: PMC5737772.
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    44. Thammavongsa V, Kim HK, Missiakas D, Schneewind O. Staphylococcal manipulation of host immune responses. Nat Rev Microbiol. 2015 Sep; 13(9):529-43. PMID: 26272408; PMCID: PMC4625792.
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    48. Thammavongsa V, Rauch S, Kim HK, Missiakas DM, Schneewind O. Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus. Vaccine. 2015 Jan 15; 33(4):523-6. PMID: 25488332; PMCID: PMC4378561.
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    49. Duan J, Shi J, Fiorentino A, Leites C, Chen X, Moy W, Chen J, Alexandrov BS, Usheva A, He D, Freda J, O'Brien NL, Molecular Genetics of Schizophrenia collaboration, Genomic Psychiatric Cohort consortium, McQuillin A, Sanders AR, Gershon ES, DeLisi LE, Bishop AR, Gurling HM, Levinson DF, Kendler KS, Gejman PV, Pato MT, Pato CN. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. Am J Hum Genet. 2014 Dec 04; 95(6):744-53. PMID: 25434007; PMCID: PMC4259974.
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    51. Pauli NT, Kim HK, Falugi F, Huang M, Dulac J, Henry Dunand C, Zheng NY, Kaur K, Andrews SF, Huang Y, DeDent A, Frank KM, Charnot-Katsikas A, Schneewind O, Wilson PC. Staphylococcus aureus infection induces protein A-mediated immune evasion in humans. J Exp Med. 2014 Nov 17; 211(12):2331-9. PMID: 25348152; PMCID: PMC4235641.
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    53. Rauch S, Gough P, Kim HK, Schneewind O, Missiakas D. Vaccine protection of leukopenic mice against Staphylococcus aureus bloodstream infection. Infect Immun. 2014 Nov; 82(11):4889-98. PMID: 25183728; PMCID: PMC4249340.
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    54. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014 Jul 24; 511(7510):421-7. PMID: 25056061; PMCID: PMC4112379.
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    55. Kim HK, Missiakas D, Schneewind O. Mouse models for infectious diseases caused by Staphylococcus aureus. J Immunol Methods. 2014 Aug; 410:88-99. PMID: 24769066; PMCID: PMC6211302.
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    56. Chan YG, Kim HK, Schneewind O, Missiakas D. The capsular polysaccharide of Staphylococcus aureus is attached to peptidoglycan by the LytR-CpsA-Psr (LCP) family of enzymes. J Biol Chem. 2014 May 30; 289(22):15680-90. PMID: 24753256; PMCID: PMC4140922.
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    57. Shi S, Leites C, He D, Schwartz D, Moy W, Shi J, Duan J. MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant. J Biol Chem. 2014 May 09; 289(19):13434-44. PMID: 24675081; PMCID: PMC4036351.
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    59. Thomer L, Becker S, Emolo C, Quach A, Kim HK, Rauch S, Anderson M, Leblanc JF, Schneewind O, Faull KF, Missiakas D. N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection. J Biol Chem. 2014 Feb 07; 289(6):3478-86. PMID: 24344128; PMCID: PMC3916549.
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    60. Kim HK, Emolo C, Missiakas D, Schneewind O. A monoclonal antibody that recognizes the E domain of staphylococcal protein A. Vaccine. 2014 Jan 16; 32(4):464-9. PMID: 24291195; PMCID: PMC6211298.
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    61. Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G, Walters GB, TAG Consortium, Oxford-GSK Consortium, ENGAGE consortium, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K. A common biological basis of obesity and nicotine addiction. Transl Psychiatry. 2013 Oct 01; 3:e308. PMID: 24084939; PMCID: PMC3818010.
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    62. Falugi F, Kim HK, Missiakas DM, Schneewind O. Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus. mBio. 2013 Aug 27; 4(5):e00575-13. PMID: 23982075; PMCID: PMC3760252.
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    78. McAdow M, Kim HK, Dedent AC, Hendrickx AP, Schneewind O, Missiakas DM. Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood. PLoS Pathog. 2011 Oct; 7(10):e1002307. PMID: 22028651; PMCID: PMC3197598.
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    79. Kim HK, Kim HY, Schneewind O, Missiakas D. Identifying protective antigens of Staphylococcus aureus, a pathogen that suppresses host immune responses. FASEB J. 2011 Oct; 25(10):3605-12. PMID: 21753082; PMCID: PMC3177580.
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      Citations: 1519     Fields:    Translation:Humans
    82. Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Parker AN, Peden JF, Petersmann A, Pichler I, Pouta A, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Melander O, Mosley TH, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Stefansson K, Frayling TM, Hirschhorn JN, Segrè AV, Mägi R, Esko T, Kutalik Z, König IR, Müller M, Kilpeläinen TO, Paré G, Pietiläinen KH, Ridderstråle M, Kähönen M, Lehtimäki T, Tönjes A, Grönberg H, Barroso I, Völzke H, Uitterlinden AG, Abecasis GR. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8. PMID: 20881960; PMCID: PMC2955183.
      Citations: 1025     Fields:    Translation:HumansCells
    83. Kim HK, Cheng AG, Kim HY, Missiakas DM, Schneewind O. Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice. J Exp Med. 2010 Aug 30; 207(9):1863-70. PMID: 20713595; PMCID: PMC2931167.
      Citations: 120     Fields:    Translation:AnimalsCells
    84. Cheng AG, McAdow M, Kim HK, Bae T, Missiakas DM, Schneewind O. Contribution of coagulases towards Staphylococcus aureus disease and protective immunity. PLoS Pathog. 2010 Aug 05; 6(8):e1001036. PMID: 20700445; PMCID: PMC2916881.
      Citations: 151     Fields:    Translation:HumansAnimalsCells
    85. Sanders AR, Levinson DF, Duan J, Dennis JM, Li R, Kendler KS, Rice JP, Shi J, Mowry BJ, Amin F, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Cloninger CR, Gejman PV. The Internet-based MGS2 control sample: self report of mental illness. Am J Psychiatry. 2010 Jul; 167(7):854-65. PMID: 20516154; PMCID: PMC6385597.
      Citations: 30     Fields:    Translation:Humans
    86. Duan J, Sanders AR, Gejman PV. Genome-wide approaches to schizophrenia. Brain Res Bull. 2010 Sep 30; 83(3-4):93-102. PMID: 20433910; PMCID: PMC2941569.
      Citations: 31     Fields:    Translation:HumansAnimals
    87. Kim HK, DeDent A, Cheng AG, McAdow M, Bagnoli F, Missiakas DM, Schneewind O. IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge. Vaccine. 2010 Aug 31; 28(38):6382-92. PMID: 20226248; PMCID: PMC3095377.
      Citations: 90     Fields:    Translation:HumansAnimals
    88. Gejman PV, Sanders AR, Duan J. The role of genetics in the etiology of schizophrenia. Psychiatr Clin North Am. 2010 Mar; 33(1):35-66. PMID: 20159339; PMCID: PMC2826121.
      Citations: 96     Fields:    Translation:Humans
    89. Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Crowe RR, Oksenberg JR, Mirel DB, Kendler KS, Freedman R, Gejman PV. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 2009 Aug 06; 460(7256):753-7. PMID: 19571809; PMCID: PMC2775422.
      Citations: 519     Fields:    Translation:HumansCells
    90. Cheng AG, Kim HK, Burts ML, Krausz T, Schneewind O, Missiakas DM. Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues. FASEB J. 2009 Oct; 23(10):3393-404. PMID: 19525403; PMCID: PMC2747682.
      Citations: 251     Fields:    Translation:AnimalsCells
    91. Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Hong SS, Honda Y, Honda M, Longstreth WT, Montplaisir J, Kemlink D, Einen M, Chen J, Musone SL, Akana M, Miyagawa T, Duan J, Desautels A, Erhardt C, Hesla PE, Poli F, Frauscher B, Jeong JH, Lee SP, Ton TG, Kvale M, Kolesar L, Nepom GT, Salomon D, Wichmann HE, Rouleau GA, Gieger C, Levinson DF, Gejman PV, Meitinger T, Young T, Peppard P, Tokunaga K, Kwok PY, Risch N, Mignot E, Högl B, Dobrovolná M. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet. 2009 Jun; 41(6):708-11. PMID: 19412176; PMCID: PMC2803042.
      Citations: 181     Fields:    Translation:HumansAnimalsCells
    92. O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, Leung HT, Hartmann AM, Morris DW, Shi Y, Feng G, Hoffmann P, Propping P, Vasilescu C, Maier W, Rietschel M, Zammit S, Schumacher J, Quinn EM, Schulze TG, Williams NM, Giegling I, Iwata N, Ikeda M, Darvasi A, Shifman S, He L, Duan J, Sanders AR, Levinson DF, Gejman PV, Cichon S, Gill M, Corvin A, Rujescu D, Kirov G, Owen MJ, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Cloninger CR, Molecular Genetics of Schizophrenia Collaboration, Möller HJ, Nöthen MM. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet. 2008 Sep; 40(9):1053-5. PMID: 18677311.
      Citations: 463     Fields:    Translation:Humans
    93. Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Crowe RR, Cloninger CR, Martinez M, Gejman PV. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Am J Psychiatry. 2008 Apr; 165(4):497-506. PMID: 18198266.
      Citations: 127     Fields:    Translation:Humans
    94. Duan J, Martinez M, Sanders AR, Hou C, Burrell GJ, Krasner AJ, Schwartz DB, Gejman PV. DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene. Hum Hered. 2007; 64(2):97-106. PMID: 17476109; PMCID: PMC2861529.
      Citations: 18     Fields:    Translation:Humans
    95. Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, Rice JP, Cox NJ, Martinez M, Mowry BJ, Amin F, Silverman JM, Black DW, Byerley WF, Crowe RR, Freedman R, Cloninger CR, Levinson DF, Gejman PV. Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. Am J Hum Genet. 2006 Feb; 78(2):315-33. PMID: 16400611; PMCID: PMC1380238.
      Citations: 53     Fields:    Translation:HumansCells
    96. Duan J, Martinez M, Sanders AR, Hou C, Krasner AJ, Schwartz DB, Gejman PV. Neuregulin 1 (NRG1 ) and schizophrenia: analysis of a US family sample and the evidence in the balance. Psychol Med. 2005 Nov; 35(11):1599-610. PMID: 16219118.
      Citations: 16     Fields:    Translation:HumansCells
    97. Duan J, Martinez M, Sanders AR, Hou C, Saitou N, Kitano T, Mowry BJ, Crowe RR, Silverman JM, Levinson DF, Gejman PV. Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. Am J Hum Genet. 2004 Oct; 75(4):624-38. PMID: 15329799; PMCID: PMC1182049.
      Citations: 30     Fields:    Translation:HumansCells
    98. Duan J, Antezana MA. Mammalian mutation pressure, synonymous codon choice, and mRNA degradation. J Mol Evol. 2003 Dec; 57(6):694-701. PMID: 14745538.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    99. Duan J, Wainwright MS, Comeron JM, Saitou N, Sanders AR, Gelernter J, Gejman PV. Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. Hum Mol Genet. 2003 Feb 01; 12(3):205-16. PMID: 12554675.
      Citations: 344     Fields:    Translation:HumansCells
    100. Sanders AR, Duan J, Gejman PV, Sanders AR, Duan J, Gejman PV. DNA variation and psychopharmacology of the human serotonin receptor 1B (HTR1B) gene. Pharmacogenomics. 2002 Nov; 3(6):745-62. PMID: 12437478.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
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