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Mark Anderson

TitlePost Doctoral Scholar
InstitutionUniversity of Chicago
DepartmentBSD Microbiology
AddressChicago IL 60637
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    Collapse Research 
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    U01DK143494     (OAKES, SCOTT A.)Aug 1, 2025 - Jun 30, 2029
    NIH
    Role of Pancreatic Elastase in Beta Cell Health, Autoimmunity and Type 1 Diabetes
    Role: Co-Principal Investigator
    R01DK137904     (GARG, ABHIMANYU)Sep 1, 2024 - Aug 31, 2028
    NIH
    Autoimmune Basis of Acquired Lipodystrophies
    Role: Co-Principal Investigator
    R01AI170841     (ANDERSON, MARK S)Aug 12, 2022 - Jul 31, 2026
    NIH
    Alterations of leukocyte integrin signaling leading to diabetes and autoimmunity
    Role: Principal Investigator
    R01DK133443     (ANDERSON, MARK S)Jun 1, 2022 - Apr 30, 2026
    NIH
    Tuning peptide specifities for T cell tolerance in Type 1 diabetes
    Role: Principal Investigator
    P01AI155393     (ANDERSON, MARK S)Feb 17, 2022 - Jan 31, 2027
    NIH
    STAT3 variants as a rheostat of immune tolerance
    Role: Principal Investigator
    T32GM141323     (KAO, AIMEE)Jul 1, 2021 - Jun 30, 2026
    NIH
    Medical Scientist Training Program (T32 NRSA Training Grant)
    Role: Co-Principal Investigator
    U01DK123559     (ANDERSON, MARK S;HEBROK, MATTHIAS ;PARENT, AUDREY ;SYKES, MEGAN)Sep 20, 2019 - May 31, 2024
    NIH
    Modeling autoimmune pathogenesis and beta cell destruction by T1D immune systems
    Role: Principal Investigator
    U01DK107383     (ANDERSON, MARK S)Jul 1, 2016 - Dec 31, 2020
    NIH
    Using human stem cell-derived thymic epithelium to remodel T1D immune tolerance
    Role: Principal Investigator
    P01AI118688     (ANDERSON, MARK S)Jun 8, 2016 - May 31, 2021
    NIH
    Disruption of T cell tolerance in type 1 diabetes
    Role: Principal Investigator
    R01DK101622     (ANDERSON, MARK S)Apr 2, 2014 - Mar 31, 2019
    NIH
    Developing eTACs as a Novel Method of Tolerance in Type 1 Diabetes
    Role: Principal Investigator
    UM1AI109565     (BUCKNER, JANE HOYT)Feb 1, 2014 - Jan 31, 2028
    NIH
    Immune Tolerance Network
    Role: Co-Principal Investigator
    R37AI097457     (ANDERSON, MARK S)Dec 1, 2011 - Jun 30, 2027
    NIH
    Thymic medullary epithelial cell turnover and control of immune tolerance
    Role: Principal Investigator
    R01AI097457     (ANDERSON, MARK S)Dec 1, 2011 - Jul 20, 2017
    NIH
    Thymic medullary epithelial cell turnover and control of immune tolerance
    Role: Principal Investigator
    R01EY016408     (ANDERSON, MARK S)Jun 1, 2005 - Jun 30, 2015
    NIH
    Aire-defieciency as a novel model of uveitis
    Role: Principal Investigator
    K08DK059958     (ANDERSON, MARK S)Sep 1, 2002 - Aug 31, 2008
    NIH
    Role of the AIRE Gene in the Development of Autoimmunity
    Role: Principal Investigator
    T32GM007618     (ANDERSON, MARK S)Jul 1, 1978 - Jun 30, 2021
    NIH
    Medical Scientist Training Program
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ohr RJ, Anderson M, Shi M, Schneewind O, Missiakas D. EssD, a Nuclease Effector of the Staphylococcus aureus ESS Pathway. J Bacteriol. 2017 01 01; 199(1). PMID: 27795323; PMCID: PMC5165103.
      Citations: 30     Fields:    Translation:AnimalsCells
    2. Anderson M, Ohr RJ, Aly KA, Nocadello S, Kim HK, Schneewind CE, Schneewind O, Missiakas D. EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection. J Bacteriol. 2017 01 01; 199(1). PMID: 27795322; PMCID: PMC5165088.
      Citations: 19     Fields:    Translation:AnimalsCells
    3. Brooks RS, Blanchard MT, Clothier KA, Fish S, Anderson ML, Stott JL. Characterization of Pajaroellobacter abortibovis, the etiologic agent of epizootic bovine abortion. Vet Microbiol. 2016 Aug 30; 192:73-80. PMID: 27527767.
      Citations: 8     Fields:    Translation:AnimalsCells
    4. Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nat Immunol. 2016 Feb; 17(2):187-95. PMID: 26726812; PMCID: PMC4718891.
      Citations: 94     Fields:    Translation:AnimalsCells
    5. LaFlam TN, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS, Seumois G. Identification of a novel cis-regulatory element essential for immune tolerance. J Exp Med. 2015 Nov 16; 212(12):1993-2002. PMID: 26527800; PMCID: PMC4647269.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    6. Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4448-57. PMID: 26216992; PMCID: PMC4538633.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    7. Anderson MS. Too much of a good thing: NLRC4 and autoinflammation. J Exp Med. 2014 Nov 17; 211(12):2329. PMID: 25403807; PMCID: PMC4235639.
      Citations:    Fields:    Translation:HumansAnimals
    8. Khan IS, Mouchess ML, Zhu ML, Conley B, Fasano KJ, Hou Y, Fong L, Su MA, Anderson MS. Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance. J Exp Med. 2014 May 05; 211(5):761-8. PMID: 24752296; PMCID: PMC4010907.
      Citations: 63     Fields:    Translation:AnimalsCells
    9. Thomer L, Becker S, Emolo C, Quach A, Kim HK, Rauch S, Anderson M, Leblanc JF, Schneewind O, Faull KF, Missiakas D. N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection. J Biol Chem. 2014 Feb 07; 289(6):3478-86. PMID: 24344128; PMCID: PMC3916549.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    10. Mohan JF, Calderon B, Anderson MS, Unanue ER. Pathogenic CD4? T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes. J Exp Med. 2013 Oct 21; 210(11):2403-14. PMID: 24127484; PMCID: PMC3804950.
      Citations: 37     Fields:    Translation:AnimalsCells
    11. Anderson M, Aly KA, Chen YH, Missiakas D. Secretion of atypical protein substrates by the ESAT-6 secretion system of Staphylococcus aureus. Mol Microbiol. 2013 Nov; 90(4):734-43. PMID: 24033479; PMCID: PMC3951145.
      Citations: 39     Fields:    Translation:Cells
    12. Shakhsheer B, Anderson M, Khatib K, Tadoori L, Joshi L, Lisacek F, Hirschman L, Mullen E. SugarBind database (SugarBindDB): a resource of pathogen lectins and corresponding glycan targets. J Mol Recognit. 2013 Sep; 26(9):426-31. PMID: 23836470.
      Citations: 7     Fields:    Translation:HumansCells
    13. Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells. Immunity. 2013 Sep 19; 39(3):560-72. PMID: 23993652; PMCID: PMC3804105.
      Citations: 76     Fields:    Translation:AnimalsCells
    14. Chen YH, Anderson M, Hendrickx AP, Missiakas D. Characterization of EssB, a protein required for secretion of ESAT-6 like proteins in Staphylococcus aureus. BMC Microbiol. 2012 Sep 25; 12:219. PMID: 23006124; PMCID: PMC3489787.
      Citations: 17     Fields:    Translation:Cells
    15. Taniguchi RT, DeVoss JJ, Moon JJ, Sidney J, Sette A, Jenkins MK, Anderson MS. Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7847-52. PMID: 22552229; PMCID: PMC3356674.
      Citations: 67     Fields:    Translation:AnimalsCellsPHPublic Health
    16. Smith BC, Anderson MA, Hoadley KA, Keck JL, Cleland WW, Denu JM. Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry. 2012 Jan 10; 51(1):243-56. PMID: 22229411; PMCID: PMC3257521.
      Citations: 6     Fields:    
    17. Anderson M, Chen YH, Butler EK, Missiakas DM. EsaD, a secretion factor for the Ess pathway in Staphylococcus aureus. J Bacteriol. 2011 Apr; 193(7):1583-9. PMID: 21278286; PMCID: PMC3067666.
      Citations: 37     Fields:    Translation:AnimalsCells
    18. Kabre BG, Davini DW, Martinier N, Su MA, DeVoss JJ, Rosenthal WL, Anderson MS, Bluestone JA, Louvet C, Bour-Jordan H. A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy. J Exp Med. 2009 Mar 16; 206(3):507-14. PMID: 19221395; PMCID: PMC2699118.
      Citations: 24     Fields:    
    19. Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, Bluestone JA. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008 Sep 01; 205(9):1983-91. PMID: 18725525; PMCID: PMC2526194.
      Citations: 230     Fields:    Translation:AnimalsCells
    20. Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science. 2008 Aug 08; 321(5890):843-7. PMID: 18687966; PMCID: PMC2532844.
      Citations: 201     Fields:    
    21. DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med. 2006 Nov 27; 203(12):2727-35. PMID: 17116738; PMCID: PMC2118158.
      Citations: 105     Fields:    Translation:Animals
    22. Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C. Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med. 2005 Sep 19; 202(6):805-15. PMID: 16172259; PMCID: PMC2212943.
      Citations: 85     Fields:    Translation:Animals
    23. Anderson MS, Lopes JM. Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1. J Biol Chem. 1996 Oct 25; 271(43):26596-601. PMID: 8900132.
      Citations: 17     Fields:    Translation:AnimalsCells
    24. Anderson MS, Kanipes MI, Jackson JC, Yates J, Henry SA, Lopes JM. Physical map locations of the phospholipid biosynthetic structural and regulatory genes of Saccharomyces cerevisiae. Yeast. 1995 Feb; 11(2):187-90. PMID: 7732728.
      Citations: 1     Fields:    Translation:AnimalsCells
    25. Anderson MS, Swier K, Arneson L, Miller J. Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal. J Exp Med. 1993 Dec 01; 178(6):1959-69. PMID: 7902408; PMCID: PMC2191285.
      Citations: 11     Fields:    Translation:AnimalsCells
    26. Naujokas MF, Morin M, Anderson MS, Peterson M, Miller J. The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44. Cell. 1993 Jul 30; 74(2):257-68. PMID: 8343954.
      Citations: 53     Fields:    Translation:AnimalsCells
    27. Anderson MS, Miller J. Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2282-6. PMID: 1549594; PMCID: PMC48641.
      Citations: 64     Fields:    Translation:AnimalsCells
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