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Christina Ciaccio

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPediatrics-Allergy & Immunology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Christina E. Ciaccio MD MSc is an Associate Professor of Pediatrics and Medicine is the Chief of Allergy/Immunology and Pediatric Pulmonology and Sleep Medicine. She was raised in rural Kankakee county which sparked her research interest in understanding how nutrition (prebiotics) and microbial exposures (probiotics) affect IgE sensitization. She currently directs the Food Allergy Program at the University of Chicago and runs a clinical translational research program in food allergy and IgE sensitization. Dr. Ciaccio is the Secretary of the Food Allergy and Eosinophilic Gastrointestinal Disease Interest Section of the American Academy of Allergy, Asthma, and Immunology and a member of the Editorial Board of the Annals of Allergy, Asthma, and Immunology.

    Collapse Biography 
    Collapse education and training
    Georgetown University School of Medicine, Washington DCMD05/2002Medicine
    The University of Notre Dame, Notre Dame, INBS05/1998Mathematics
    The University of Kansas School of Medicine, Kansas City, KSMS05/2014Clinical Research
    McGaw Medical Center at Northwestern, Chicago, IL06/2005Internal Medicine
    McGaw Medical Center at Northwestern, Chicago, IL06/2006Allergy/Immunology
    Children's Mercy Hospital, Kansas City, MO06/2008Allergy/Immunology
    Collapse awards and honors
    2002Sarah E. Stewart Leadership Award, Georgetown University School of Medicine
    2004Outstanding Teaching Award, Northwestern University Feinberg School of Medicine
    2011 - 2012Young Faculty Award, American College of Allergy, Asthma, and Immunology
    2013 - 2014Paul Henson Clinical Scholar Award, Children's Mercy, Kansas City
    2013Golden Apple Award for Teaching and Mentoring, Children's Mercy, Kansas City
    2015Golden Apple Award for Teaching and Mentoring, Children's Mercy, Kansas City
    20177 Best Allergists in Chicago, Spokin
    2019Best Allergists in the Country, Spokin

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gupta RS, Sehgal S, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Nimmagadda SR, Assa'ad A, Mahdavinia M, Wasserman RL, Brown E, Sicherer SH, Bird JA, Roberts B, Sharma HP, Mendez K, Holding EG, Mitchell L, Corbett M, Makhija M, Starren JB. Accelerating Food Allergy Research: Need for a Data Commons. J Allergy Clin Immunol Pract. 2023 04; 11(4):1063-1067. PMID: 36796512.
      Citations:    Fields:    Translation:Humans
    2. Kraft A, Ciaccio CE. Diagnostic Testing Procedures and Challenges for Primary Immunodeficiencies. Pediatr Ann. 2022 Dec; 51(12):e480-e484. PMID: 36476200.
      Citations:    Fields:    
    3. Mayampurath A, Ajith A, Anderson-Smits C, Chang SC, Brouwer E, Johnson J, Baltasi M, Volchenboum S, Devercelli G, Ciaccio CE. Early Diagnosis of Primary Immunodeficiency Disease Using Clinical Data and Machine Learning. J Allergy Clin Immunol Pract. 2022 11; 10(11):3002-3007.e5. PMID: 36108921.
      Citations: 1     Fields:    Translation:Humans
    4. Ciaccio C, Goldsobel AB, Anagnostou A, Beyer K, Casale TB, Deschildre A, Fern?ndez-Rivas M, Hourihane JO, Krawiec M, Lieberman J, Scurlock AM, Vickery BP, Smith A, Tilles SA, Adelman DC, Brown KR, RAMSES (ARC007) and ARC011 Study Groups:. Participant characteristics and safety outcomes of peanut oral immunotherapy in the RAMSES and ARC011 trials. Ann Allergy Asthma Immunol. 2022 Dec; 129(6):758-768.e4. PMID: 35973655.
      Citations:    Fields:    Translation:HumansAnimalsCTClinical Trials
    5. Portnoy J, Ciaccio CE, Beausoleil J, Du Toit G, Fineman S, Tilles SA, Zhang J, Lawrence C, Yassine M, Mustafa SS. Eight tips for the implementation of the first licenced peanut allergy oral immunotherapy into clinical practice. Allergy Asthma Clin Immunol. 2022 May 09; 18(1):37. PMID: 35534909; PMCID: PMC9088027.
      Citations: 1     
    6. Volerman A, Pelczar A, Conti R, Ciaccio C, Chua KP. Association between dispensing of low-value oral albuterol and removal from Medicaid preferred drug lists. BMC Health Serv Res. 2022 Apr 26; 22(1):562. PMID: 35473608; PMCID: PMC9044602.
      Citations:    Fields:    Translation:Humans
    7. Sehgal S, Gupta RS, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Makhija M, Starren JB. Development of Food Allergy Data Dictionary: Toward a Food Allergy Data Commons. J Allergy Clin Immunol Pract. 2022 06; 10(6):1614-1621.e1. PMID: 35259539.
      Citations:    Fields:    Translation:Humans
    8. Hwang DW, Nagler CR, Ciaccio CE. New and emerging concepts and therapies for the treatment of food allergy. Immunother Adv. 2022; 2(1):ltac006. PMID: 35434724; PMCID: PMC9007422.
      Citations:    
    9. Shroba J, Das R, Bilaver L, Vincent E, Brown E, Polk B, Ramos A, Russell AF, Bird JA, Ciaccio CE, Lanser BJ, Mudd K, Sood A, Vickery BP, Gupta R. Food Insecurity in the Food Allergic Population: A?Work Group Report of the AAAAI Adverse Reactions to Foods Committee. J Allergy Clin Immunol Pract. 2022 01; 10(1):81-90. PMID: 34862158.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    10. Kim SL, Suresh R, Mayampurath A, Ciaccio CE. Increase in Epinephrine Administration for Food-Induced Anaphylaxis in Pediatric Emergency Departments From 2007 to 2015. J Allergy Clin Immunol Pract. 2022 01; 10(1):200-205.e1. PMID: 34563738.
      Citations: 2     Fields:    Translation:Humans
    11. Brough HA, Lanser BJ, Sindher SB, Teng JMC, Leung DYM, Venter C, Chan SM, Santos AF, Bahnson HT, Guttman-Yassky E, Gupta RS, Lack G, Ciaccio CE, Sampath V, Nadeau KC, Nagler CR. Early intervention and prevention of allergic diseases. Allergy. 2022 02; 77(2):416-441. PMID: 34255344.
      Citations: 8     Fields:    Translation:Humans
    12. Guillaume JD, Jagai JS, Makelarski JA, Abramsohn EM, Lindau ST, Verma R, Ciaccio CE. COVID-19-Related Food Insecurity Among Households with Dietary Restrictions: A National Survey. J Allergy Clin Immunol Pract. 2021 09; 9(9):3323-3330.e3. PMID: 34174493; PMCID: PMC8421756.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    13. Vickery BP, Vereda A, Nilsson C, du Toit G, Shreffler WG, Burks AW, Jones SM, Fern?ndez-Rivas M, Bl?mchen K, O'B Hourihane J, Beyer K, Anagnostou A, Assa'ad AH, Ben-Shoshan M, Bird JA, Carr TF, Carr WW, Casale TB, Chong HJ, Ciaccio CE, Dorsey MJ, Fineman SM, Fritz SB, Greiner AN, Greos LS, Hampel FC, Ib??ez MD, Jeong DK, Johnston DT, Kachru R, Kim EH, Lanser BJ, Leonard SA, Maier MC, Mansfield LE, Muraro A, Ohayon JA, Oude Elberink JNG, Petroni DH, Pongracic JA, Portnoy JM, Rachid R, Rupp NT, Sanders GM, Sharma HP, Sharma V, Sher ER, Sher L, Sindher SB, Siri D, Spergel JM, Sprikkelman AB, Sussman GL, Tsoumani M, Varshney P, Vitalpur G, Wang J, Yang WH, Zubeldia JM, Smith A, Ryan R, Adelman DC. Continuous and Daily Oral Immunotherapy for Peanut Allergy: Results from a 2-Year Open-Label Follow-On Study. J Allergy Clin Immunol Pract. 2021 05; 9(5):1879-1889.e13. PMID: 33359589.
      Citations: 11     Fields:    Translation:HumansAnimals
    14. Kanaley MK, Dyer AA, Negris OR, Fierstein JL, Ciaccio CE, Gupta RS, Bilaver LA. Guideline-informed care among Medicaid-enrolled children with food allergy. Am J Manag Care. 2020 12; 26(12):505-512. PMID: 33315325.
      Citations:    Fields:    Translation:Humans
    15. Pepper AN, Assa'ad A, Blaiss M, Brown E, Chinthrajah S, Ciaccio C, Fasano MB, Gupta R, Hong N, Lang D, Mahr T, Malawer E, Roach A, Shreffler W, Sicherer S, Vickers K, Vickery BP, Wasserman R, Yates K, Casale TB. Consensus report from the Food Allergy Research & Education (FARE) 2019 Oral Immunotherapy for Food Allergy Summit. J Allergy Clin Immunol. 2020 08; 146(2):244-249. PMID: 32505612.
      Citations: 4     Fields:    Translation:HumansAnimals
    16. Altman MC, Beigelman A, Ciaccio C, Gern JE, Heymann PW, Jackson DJ, Kennedy JL, Kloepfer K, Lemanske RF, McWilliams LM, Muehling L, Nance C, Peebles RS. Evolving concepts in how viruses impact asthma: A Work Group Report of the Microbes in Allergy Committee of the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2020 05; 145(5):1332-1344. PMID: 31926183; PMCID: PMC7577409.
      Citations: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    17. Makhija MM, Ciaccio CE. Pediatric Allergy and Immunology. Pediatr Ann. 2019 Dec 01; 48(12):e466-e467. PMID: 31830284.
      Citations:    Fields:    Translation:Humans
    18. Ciaccio CE, Bauer ME, Nowak-Wegrzyn A. Food OIT: What do we know, what don't we know, and what do we need to know? Ann Allergy Asthma Immunol. 2019 08; 123(2):118-119. PMID: 31376842.
      Citations:    Fields:    Translation:Humans
    19. Casale TB, Haselkorn T, Ciaccio CE, Sriaroon P, Chipps BE. Harmonization of Terminology for Tolerated and Reactive Dose in Food Allergy Immunotherapy. J Allergy Clin Immunol Pract. 2019 02; 7(2):389-392. PMID: 30557719.
      Citations: 2     Fields:    Translation:Humans
    20. Chipps BE, Ciaccio CE, Ros?n K, Haselkorn T, Zigmont E, Casale TB. Real-world attitudes among allergists/immunologists regarding oral immunotherapy and preferred terminology. J Allergy Clin Immunol Pract. 2019 02; 7(2):721-723.e9. PMID: 30557711.
      Citations: 2     Fields:    Translation:HumansAnimals
    21. Ciaccio CE. Modulating the microbiome: The future of allergy therapeutics? Ann Allergy Asthma Immunol. 2019 03; 122(3):233-235. PMID: 30552985.
      Citations: 2     Fields:    Translation:Humans
    22. PALISADE Group of Clinical Investigators, Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ib??ez MD, Tilles S, Assa?ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC, Kim EH, Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fern?ndez-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW. AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med. 2018 Nov 22; 379(21):1991-2001. PMID: 30449234.
      Citations: 141     Fields:    Translation:HumansAnimalsCTClinical Trials
    23. Zhu L, Ciaccio CE, Casale TB. Potential new targets for drug development in severe asthma. World Allergy Organ J. 2018; 11(1):30. PMID: 30386455; PMCID: PMC6203275.
      Citations: 13     
    24. Colombi M, Dordoni C, Venturini M, Ciaccio C, Morlino S, Chiarelli N, Zanca A, Calzavara-Pinton P, Zoppi N, Castori M, Ritelli M. Spectrum of mucocutaneous, ocular and facial features and delineation of novel presentations in 62 classical Ehlers-Danlos syndrome patients. Clin Genet. 2017 Dec; 92(6):624-631. PMID: 28485813.
      Citations: 14     Fields:    Translation:Humans
    25. Shroba J, Barnes C, Nanda M, Dinakar C, Ciaccio C. Ara h2 levels in dust from homes of individuals with peanut allergy and individuals with peanut tolerance. Allergy Asthma Proc. 2017 May 01; 38(3):192-196. PMID: 28441989; PMCID: PMC6479458.
      Citations: 6     Fields:    Translation:HumansAnimalsPHPublic Health
    26. Chan MA, Ciaccio CE, Gigliotti NM, Rezaiekhaligh M, Siedlik JA, Kennedy K, Barnes CS. DNA methylation levels associated with race and childhood asthma severity. J Asthma. 2017 Oct; 54(8):825-832. PMID: 27929694.
      Citations: 8     Fields:    Translation:HumansCells
    27. Ciaccio CE, Gurley-Calvez T, Shireman TI. Indoor tobacco legislation is associated with fewer emergency department visits for asthma exacerbation in children. Ann Allergy Asthma Immunol. 2016 12; 117(6):641-645. PMID: 27979021; PMCID: PMC5166981.
      Citations: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    28. Ciaccio CE, Barnes C, Kennedy K, Chan M, Portnoy J, Rosenwasser L. Home dust microbiota is disordered in homes of low-income asthmatic children. J Asthma. 2015; 52(9):873-80. PMID: 26512904; PMCID: PMC4807694.
      Citations: 14     Fields:    Translation:HumansCells
    29. Ciaccio CE, DiDonna A, Kennedy K, Barnes CS, Portnoy JM, Rosenwasser LJ. Secondhand tobacco smoke exposure in low-income children and its association with asthma. Allergy Asthma Proc. 2014 Nov-Dec; 35(6):462-6. PMID: 25584913; PMCID: PMC4210654.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    30. Pacheco CM, Ciaccio CE, Nazir N, Daley CM, DiDonna A, Choi WS, Barnes CS, Rosenwasser LJ. Homes of low-income minority families with asthmatic children have increased condition issues. Allergy Asthma Proc. 2014 Nov-Dec; 35(6):467-74. PMID: 25584914; PMCID: PMC4210655.
      Citations: 11     Fields:    Translation:Humans
    31. Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson ED, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O'Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes JD, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood. 2015 Jan 22; 125(4):591-9. PMID: 25359994; PMCID: PMC4304103.
      Citations: 208     Fields:    Translation:HumansCellsCTClinical Trials
    32. Raje N, Soden S, Swanson D, Ciaccio CE, Kingsmore SF, Dinwiddie DL. Utility of next generation sequencing in clinical primary immunodeficiencies. Curr Allergy Asthma Rep. 2014 Oct; 14(10):468. PMID: 25149170; PMCID: PMC4582650.
      Citations: 14     Fields:    Translation:Humans
    33. Ciaccio CE, Girdhar M. Effect of maternal ?3 fatty acid supplementation on infant allergy. Ann Allergy Asthma Immunol. 2014 Mar; 112(3):191-4. PMID: 24565593; PMCID: PMC3961846.
      Citations: 5     Fields:    Translation:Humans
    34. Rittenour WR, Ciaccio CE, Barnes CS, Kashon ML, Lemons AR, Beezhold DH, Green BJ. Internal transcribed spacer rRNA gene sequencing analysis of fungal diversity in Kansas City indoor environments. Environ Sci Process Impacts. 2014 Jan; 16(1):33-43. PMID: 24258337; PMCID: PMC3966654.
      Citations: 27     Fields:    Translation:AnimalsPHPublic Health
    35. Ciaccio CE, Gentile D. Effects of tobacco smoke exposure in childhood on atopic diseases. Curr Allergy Asthma Rep. 2013 Dec; 13(6):687-92. PMID: 24057650; PMCID: PMC3840144.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    36. Ciaccio CE, DiDonna AC, Kennedy K, Barnes CS, Portnoy JM, Rosenwasser LJ. Association of tobacco smoke exposure and atopic sensitization. Ann Allergy Asthma Immunol. 2013 Nov; 111(5):387-90. PMID: 24125146; PMCID: PMC3869197.
      Citations: 10     Fields:    Translation:HumansAnimalsPHPublic Health
    37. Barnes C, Portnoy JM, Ciaccio CE, Pacheco F. A comparison of subject room dust with home vacuum dust for evaluation of dust-borne aeroallergens. Ann Allergy Asthma Immunol. 2013 May; 110(5):375-9. PMID: 23622010; PMCID: PMC3870589.
      Citations: 8     Fields:    Translation:PHPublic Health
    38. Ciaccio CE, Kennedy K, Portnoy JM. A new model for environmental assessment and exposure reduction. Curr Allergy Asthma Rep. 2012 Dec; 12(6):650-5. PMID: 22933137; PMCID: PMC3493798.
      Citations: 4     Fields:    Translation:HumansAnimalsPHPublic Health
    39. Vesper S, Barnes C, Ciaccio CE, Johanns A, Kennedy K, Murphy JS, Nunez-Alvarez A, Sandel MT, Cox D, Dewalt G, Ashley PJ. Higher Environmental Relative Moldiness Index (ERMI) values measured in homes of asthmatic children in Boston, Kansas City, and San Diego. J Asthma. 2013 Mar; 50(2):155-61. PMID: 23137280; PMCID: PMC3874819.
      Citations: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    40. Ciaccio CE, Portnoy JM. Spacers and valved holding chambers in asthma drug delivery: how many breaths are needed to achieve adequate lung deposition? Curr Allergy Asthma Rep. 2011 Dec; 11(6):445-6. PMID: 21901303.
      Citations:    Fields:    
    41. Ciaccio CE. Angioedema: an overview and update. Mo Med. 2011 Sep-Oct; 108(5):354-7. PMID: 22073494; PMCID: PMC6188378.
      Citations:    Fields:    Translation:Humans
    42. Jacobs Z, Ciaccio CE. Periodic Fever syndromes. Curr Allergy Asthma Rep. 2010 Nov; 10(6):398-404. PMID: 20734171.
      Citations: 6     Fields:    Translation:Humans
    43. Ciaccio CE, Portnoy JM. Vitamin D insufficiency and risk of severe asthma exacerbations. Curr Allergy Asthma Rep. 2010 Nov; 10(6):387-8. PMID: 20725812.
      Citations: 5     Fields:    
    44. Lupoli TA, Ciaccio CE, Portnoy JM. Home and school environmental assessment and remediation. Curr Allergy Asthma Rep. 2009 Nov; 9(6):419-25. PMID: 19814913.
      Citations:    Fields:    Translation:HumansPHPublic Health
    45. Johnson L, Ciaccio C, Barnes CS, Kennedy K, Forrest E, Gard LC, Pacheco F, Dowling P, Portnoy JM. Low-cost interventions improve indoor air quality and children's health. Allergy Asthma Proc. 2009 Jul-Aug; 30(4):377-85. PMID: 19772759.
      Citations: 12     Fields:    Translation:HumansAnimalsPHPublic Health
    46. Ramos C, Ciaccio C, Portnoy JM. Asthma control is enhanced when health plans and providers cooperate. Pediatr Ann. 2009 Mar; 38(3):135-42. PMID: 19353902.
      Citations:    Fields:    Translation:Humans
    47. Ciaccio CE, Portnoy JM. Strategies for primary prevention of atopy in children. Curr Allergy Asthma Rep. 2008 Nov; 8(6):493-9. PMID: 18940139.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    48. Robin J, Weinberg K, Tiongson J, Carnethon M, Reddy M, Ciaccio C, Quadrini M, Hsu J, Fan J, Choi P, Kadish A, Goldberger J, Passman R. Renal dialysis as a risk factor for appropriate therapies and mortality in implantable cardioverter-defibrillator recipients. Heart Rhythm. 2006 Oct; 3(10):1196-201. PMID: 17018351.
      Citations: 22     Fields:    Translation:Humans
    49. Chiu B, Ciaccio C, West MA. Intestinal obstruction from furniture cushion foam bezoar. Surgery. 2005 Nov; 138(5):956-8. PMID: 16291400.
      Citations: 5     Fields:    Translation:Humans
    50. Di Marco V, Lo Iacono O, Almasio P, Ciaccio C, Capra M, Rizzo M, Malizia R, Maggio A, Fabiano C, Barbaria F, Crax? A. Long-term efficacy of alpha-interferon in beta-thalassemics with chronic hepatitis C. Blood. 1997 Sep 15; 90(6):2207-12. PMID: 9310471.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    51. Mansueto S, Di Leo R, Vitale G, Casandra F, Gallarano P, Ciaccio C, Occhino C. [Enzymatic parameters in boutonneuse fever. II. Behavior and significance of lactic dehydrogenase]. Boll Ist Sieroter Milan. 1983 Jul; 62(3):292-7. PMID: 6639781.
      Citations:    Fields:    Translation:Humans
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