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Cevher Ozcan

TitleAssociate Professor
InstitutionUniversity of Chicago
AddressChicago IL 60637
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    K08HL117082     (OZCAN, CEVHER)May 1, 2014 - Oct 31, 2019
    Mitochondrial Mechanisms and Novel Therapeutic Targets in Atrial Fibrillation
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cetin-Atalay R, Meliton AY, Ozcan C, Woods PS, Sun KA, Fang Y, Hamanaka RB, Mutlu GM. Loss of heme oxygenase 2 causes reduced expression of genes in cardiac muscle development and contractility and leads to cardiomyopathy in mice. PLoS One. 2023; 18(10):e0292990. PMID: 37844118; PMCID: PMC10578579.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Dixit G, Blair J, Ozcan C. Plasma proteomic analysis of association between atrial fibrillation, coronary microvascular disease and heart failure. Am J Cardiovasc Dis. 2022; 12(2):81-91. PMID: 35600285; PMCID: PMC9123414.
      Citations: 2     
    3. Allaw AB, Mittal S, Merchant FM, Besser SA, Beaser AD, Aziz Z, Ozcan C, Nayak HM, Tung R, Upadhyay GA. Population-Level Impact of the Guidelines Update on Patient Selection and Outcomes After Cardiac Resynchronization Therapy. JACC Clin Electrophysiol. 2022 05; 8(5):651-661. PMID: 35589178.
      Citations: 1     Fields:    Translation:Humans
    4. Kohli U, Hazra A, Shahab A, Beaser AD, Aziz ZA, Upadhyay GA, Ozcan C, Tung R, Nayak HM. Atypical pathogens associated with cardiac implantable electronic device infections. Pacing Clin Electrophysiol. 2021 Sep; 44(9):1549-1561. PMID: 34245025; PMCID: PMC9290787.
      Citations: 4     Fields:    Translation:Humans
    5. Upadhyay GA, Henry M, Genovese D, Desai P, Lattell J, Wey H, Besser SA, Aziz Z, Beaser AD, Ozcan C, Nayak HM, Lang RM, Tung R. Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing. Heart Rhythm O2. 2021 Oct; 2(5):446-454. PMID: 34667959; PMCID: PMC8505206.
      Citations: 2     
    6. Ozcan C. Conduction Intervals and Atrial Fibrillation in Chronic Kidney Disease. Am J Nephrol. 2021; 52(5):354-355. PMID: 33971643.
      Citations: 1     Fields:    Translation:Humans
    7. Ozcan C, Allan T, Besser SA, de la Pena A, Blair J. The relationship between coronary microvascular dysfunction, atrial fibrillation and heart failure with preserved ejection fraction. Am J Cardiovasc Dis. 2021; 11(1):29-38. PMID: 33815917; PMCID: PMC8012292.
      Citations: 5     
    8. Nishimura T, Patel HN, Wang S, Upadhyay GA, Smith HL, Ozcan C, Shatz DY, Nayak HM, Patel AR, Tung R. Prognostic value of cardiac magnetic resonance septal late gadolinium enhancement patterns for periaortic ventricular tachycardia ablation: Heterogeneity of the anteroseptal substrate in nonischemic cardiomyopathy. Heart Rhythm. 2021 04; 18(4):579-588. PMID: 33301979; PMCID: PMC8026601.
      Citations: 2     Fields:    Translation:Humans
    9. Nayak HM, Aziz ZA, Kwasnik A, Lee E, Shatz DY, Tenorio R, Besser SA, Beaser AD, Ozcan C, Upadhyay GA, Tung R. Indirect and Direct Evidence for 3-D Activation During Left Atrial Flutter: Anatomy of Epicardial Bridging. JACC Clin Electrophysiol. 2020 12; 6(14):1812-1823. PMID: 33357578.
      Citations: 7     Fields:    Translation:Humans
    10. Ozcan C, Dixit G, Li Z. Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation. J Cardiovasc Transl Res. 2021 06; 14(3):492-502. PMID: 32844365.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    11. Liao H, Wei W, Tanager KS, Miele F, Upadhyay GA, Beaser AD, Aziz Z, Nayak HM, Ozcan C, Nishimura T, Jiang R, Shatz D, Husain AN, Tung R. Left ventricular summit arrhythmias with an abrupt V3 transition: Anatomy of the aortic interleaflet triangle vantage point. Heart Rhythm. 2021 01; 18(1):10-19. PMID: 32707175.
      Citations: 8     Fields:    Translation:Humans
    12. Beaser AD, Aziz Z, Besser SA, Jones CI, Jameria Z, Kannan A, Upadhyay GA, Broman MT, Ozcan C, Tung R, Nayak HM. Characterization of Lead Adherence Using Intravascular Ultrasound to Assess Difficulty of Transvenous Lead Extraction. Circ Arrhythm Electrophysiol. 2020 08; 13(8):e007726. PMID: 32628867.
      Citations: 6     Fields:    Translation:Humans
    13. Ozcan C, Deshmukh A. Atrial arrhythmias in patients with left ventricular assist devices. Curr Opin Cardiol. 2020 05; 35(3):276-281. PMID: 32097178; PMCID: PMC7138730.
      Citations: 3     Fields:    Translation:Humans
    14. Nishimura T, Beaser AD, Aziz ZA, Upadhyay GA, Ozcan C, Raiman M, Shatz DY, Besser SA, Shatz NA, Nayak HM, Tung R. Periaortic ventricular tachycardia in structural heart disease: Evidence of localized reentrant mechanisms. Heart Rhythm. 2020 08; 17(8):1271-1279. PMID: 32325198.
      Citations: 5     Fields:    Translation:Humans
    15. Upadhyay GA, Cherian T, Shatz DY, Beaser AD, Aziz Z, Ozcan C, Broman MT, Nayak H, Tung R. Response by Upadhyay et al to Letter Regarding Article, "Intracardiac Delineation of Septal Conduction in Left Bundle-Branch Block Patterns: Mechanistic Evidence of Left Intrahisian Block Circumvented by His Bundle Pacing". Circulation. 2019 10; 140(14):e713-e714. PMID: 31567009.
      Citations: 1     Fields:    Translation:Humans
    16. Ozcan C, Li Z, Kim G, Jeevanandam V, Uriel N. Molecular Mechanism of the Association Between Atrial Fibrillation and Heart Failure Includes Energy Metabolic Dysregulation Due to Mitochondrial Dysfunction. J Card Fail. 2019 Nov; 25(11):911-920. PMID: 31415862; PMCID: PMC7144800.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    17. Upadhyay GA, Cherian T, Shatz DY, Beaser AD, Aziz Z, Ozcan C, Broman MT, Nayak HM, Tung R. Intracardiac Delineation of Septal Conduction in Left Bundle-Branch Block Patterns. Circulation. 2019 04 16; 139(16):1876-1888. PMID: 30704273.
      Citations: 77     Fields:    Translation:Humans
    18. Tung R, Ozcan C. Atrial Arrhythmias in Patients With Left Ventricular Assist Devices: To Treat or Not to Treat? JACC Clin Electrophysiol. 2019 04; 5(4):467-469. PMID: 31000100; PMCID: PMC7144789.
      Citations:    Fields:    Translation:Humans
    19. Guo J, Nayak HM, Besser SA, Beaser A, Aziz Z, Broman M, Ozcan C, Tung R, Upadhyay GA. Impact of Atrial Fibrillation Ablation on Recurrent Hospitalization: A Nationwide Cohort Study. JACC Clin Electrophysiol. 2019 03; 5(3):330-339. PMID: 30898236.
      Citations: 7     Fields:    Translation:Humans
    20. Deshmukh A, Bhatia A, Sayer GT, Kim G, Raikhelkar J, Imamura T, Ozcan C, Ota T, Jeevanandam V, Uriel N. Left Atrial Appendage Occlusion With Left Ventricular Assist Device Decreases Thromboembolic Events. Ann Thorac Surg. 2019 04; 107(4):1181-1186. PMID: 30365959.
      Citations: 10     Fields:    Translation:Humans
    21. Bukari A, Wali E, Deshmukh A, Aziz Z, Broman M, Beaser A, Upadhyay G, Nayak H, Tung R, Ozcan C. Prevalence and predictors of atrial arrhythmias in patients with sinus node dysfunction and atrial pacing. J Interv Card Electrophysiol. 2018 Dec; 53(3):365-371. PMID: 30293095; PMCID: PMC7134386.
      Citations: 4     Fields:    Translation:Humans
    22. Deshmukh A, Bhatia A, Anyanwu E, Ota T, Jeevanandam V, Uriel N, Tung R, Ozcan C. Incidence and Outcomes of Postoperative Atrial Fibrillation After Left Ventricular Assist Device. ASAIO J. 2018 Sep/Oct; 64(5):581-585. PMID: 29485424; PMCID: PMC7055419.
      Citations: 4     Fields:    Translation:Humans
    23. Wali E, Deshmukh A, Bukari A, Broman M, Aziz Z, Beaser A, Upadhyay G, Nayak HM, Tung R, Ozcan C. Impact of high-grade atrioventricular block and cumulative frequent pacing on atrial arrhythmias. Pacing Clin Electrophysiol. 2018 09; 41(9):1158-1164. PMID: 29931776; PMCID: PMC7144804.
      Citations: 2     Fields:    Translation:Humans
    24. Chua K, Upadhyay GA, Lee E, Aziz Z, Beaser AD, Ozcan C, Broman M, Nayak HM, Tung R. High-resolution mapping of the triangle of Koch: Spatial heterogeneity of fast pathway atrionodal connections. Heart Rhythm. 2018 03; 15(3):421-429. PMID: 29081398.
      Citations: 6     Fields:    Translation:Humans
    25. Bukari A, Nayak H, Aziz Z, Deshmukh A, Tung R, Ozcan C. Impact of race and gender on clinical outcomes of catheter ablation in patients with atrial fibrillation. Pacing Clin Electrophysiol. 2017 Oct; 40(10):1073-1079. PMID: 28842917; PMCID: PMC5810413.
      Citations: 6     Fields:    Translation:Humans
    26. Deshmukh A, Ozcan C. Symptomatic Long Pauses and Bradycardia due to Massive Multinodular Goiter. Case Rep Cardiol. 2017; 2017:4201942. PMID: 28845312; PMCID: PMC5563397.
    27. Benes LB, Rosenberg JR, Ozcan C, Cherian TS, Shah AP. Intravascular ultrasound to assess for baffle stenosis after Mustard procedure. Int J Cardiovasc Imaging. 2017 Aug; 33(8):1113-1114. PMID: 28285329.
      Citations:    Fields:    Translation:Humans
    28. Deshmukh A, Kim G, Burke M, Anyanwu E, Uriel N, Tung R, Ozcan C, Jeevanandam V. Atrial Arrhythmias and Electroanatomical Remodeling in Patients With Left Ventricular Assist Devices. J Am Heart Assoc. 2017 Mar 08; 6(3). PMID: 28275069; PMCID: PMC5524037.
      Citations: 21     Fields:    Translation:Humans
    29. Stone J, Balkhy H, Ozcan C. Unique case of papillary fibroelastoma originating from the right interatrial septum. Int J Cardiol. 2016 Nov 15; 223:251-253. PMID: 27541666.
      Citations:    Fields:    Translation:Humans
    30. Narang A, Ozcan C. Severe Torsades de Pointes with acquired QT prolongation. Eur Heart J Acute Cardiovasc Care. 2019 Dec; 8(8):775-776. PMID: 27154527.
      Citations: 2     Fields:    Translation:Humans
    31. Weil BR, Ozcan C. Cardiomyocyte Remodeling in Atrial Fibrillation and Hibernating Myocardium: Shared Pathophysiologic Traits Identify Novel Treatment Strategies? Biomed Res Int. 2015; 2015:587361. PMID: 26221599; PMCID: PMC4499626.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    32. Ozcan C, Battaglia E, Young R, Suzuki G. LKB1 knockout mouse develops spontaneous atrial fibrillation and provides mechanistic insights into human disease process. J Am Heart Assoc. 2015 Mar 15; 4(3):e001733. PMID: 25773299; PMCID: PMC4392447.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    33. Ozcan C, Strom JB, Newell JB, Mansour MC, Ruskin JN. Incidence and predictors of atrial fibrillation and its impact on long-term survival in patients with supraventricular arrhythmias. Europace. 2014 Oct; 16(10):1508-14. PMID: 24906607.
      Citations: 10     Fields:    Translation:Humans
    34. Ozcan C, Barrett CD. Ventricular arrhythmias and left ventricular assist device. Int J Cardiol. 2013 Sep 30; 168(2):e81-3. PMID: 23890887.
      Citations:    Fields:    Translation:Humans
    35. Ozcan C, Barrett CD. Utility of intracardiac echocardiography for catheter ablation of an anteroseptal accessory pathway from the non-coronary aortic cusp. Int J Cardiol. 2013 Sep 10; 167(6):e153-5. PMID: 23664440.
      Citations: 1     Fields:    Translation:Humans
    36. Ozcan C, Palmeri M, Horvath TL, Russell KS, Russell RR. Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning. Am J Physiol Heart Circ Physiol. 2013 May; 304(9):H1192-200. PMID: 23457013; PMCID: PMC3652089.
      Citations: 49     Fields:    Translation:AnimalsCells
    37. Ozcan C, Rottman JN, Heist EK, Guy ML, Ellinor PT, Singh J, Milan DJ, Danik SB, Barrett CD, Mansour M, Ruskin JN, Mela T. Unpredictable battery depletion of St Jude Atlas II and Atlas+ II HF implantable cardioverter-defibrillators. Heart Rhythm. 2012 May; 9(5):717-20. PMID: 22172318.
      Citations: 3     Fields:    Translation:Humans
    38. Ozcan C, Ruskin J, Mansour M. Cryoballoon catheter ablation in atrial fibrillation. Cardiol Res Pract. 2011; 2011:256347. PMID: 21747987; PMCID: PMC3130969.
      Citations: 2     
    39. Lubitz SA, Ozcan C, Magnani JW, Benjamin EJ, Ellinor PT, Kääb S. Genetics of atrial fibrillation: implications for future research directions and personalized medicine. Circ Arrhythm Electrophysiol. 2010 Jun; 3(3):291-9. PMID: 20551423; PMCID: PMC3062900.
      Citations: 23     Fields:    Translation:HumansAnimals
    40. Ozcan C, Zaret BL. Dobutamine stress test and beta-agonist - a potential concern for nuclear cardiology testing: a case report. Cases J. 2009 Jul 09; 2:7466. PMID: 19829971; PMCID: PMC2740317.
    41. Chen L, Hodge D, Jahangir A, Ozcan C, Trusty J, Friedman P, Rea R, Bradley D, Brady P, Hammill S, Hayes D, Shen WK. Preserved left ventricular ejection fraction following atrioventricular junction ablation and pacing for atrial fibrillation. J Cardiovasc Electrophysiol. 2008 Jan; 19(1):19-27. PMID: 17971146.
      Citations: 18     Fields:    Translation:Humans
    42. Ozcan C, Terzic A, Bienengraeber M. Effective pharmacotherapy against oxidative injury: alternative utility of an ATP-sensitive potassium channel opener. J Cardiovasc Pharmacol. 2007 Oct; 50(4):411-8. PMID: 18049309.
      Citations: 13     Fields:    Translation:AnimalsCells
    43. Ozcan C, Bienengraeber M, Hodgson DM, Mann DL, Terzic A. Mitochondrial tolerance to stress impaired in failing heart. J Mol Cell Cardiol. 2003 Sep; 35(9):1161-6. PMID: 12967639.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Ozcan C, Jahangir A, Friedman PA, Munger TM, Packer DL, Hodge DO, Hayes DL, Gersh BJ, Hammill SC, Shen WK. Significant effects of atrioventricular node ablation and pacemaker implantation on left ventricular function and long-term survival in patients with atrial fibrillation and left ventricular dysfunction. Am J Cardiol. 2003 Jul 01; 92(1):33-7. PMID: 12842241.
      Citations: 10     Fields:    Translation:Humans
    45. Dzeja PP, Bast P, Ozcan C, Valverde A, Holmuhamedov EL, Van Wylen DG, Terzic A. Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection. Am J Physiol Heart Circ Physiol. 2003 Apr; 284(4):H1048-56. PMID: 12666660.
      Citations: 45     Fields:    Translation:AnimalsCells
    46. Ozcan C, Jahangir A, Friedman PA, Hayes DL, Munger TM, Rea RF, Lloyd MA, Packer DL, Hodge DO, Gersh BJ, Hammill SC, Shen WK. Sudden death after radiofrequency ablation of the atrioventricular node in patients with atrial fibrillation. J Am Coll Cardiol. 2002 Jul 03; 40(1):105-10. PMID: 12103263.
      Citations: 17     Fields:    Translation:Humans
    47. Ozcan C, Bienengraeber M, Dzeja PP, Terzic A. Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H531-9. PMID: 11788400.
      Citations: 51     Fields:    Translation:AnimalsCells
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