Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease.

Histopathologic Evaluation and Single-cell Spatial Transcriptomics of the Colon Reveal Cellular and Molecular Abnormalities Linked to J-Pouch Failure in Patients With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2025; 19(10):101563.

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subject areas

Adult
Case-Control Studies
Colectomy
Colitis, Ulcerative
Colon
Colonic Pouches
Crohn Disease
Female
Gene Expression Profiling
Humans
Inflammatory Bowel Diseases
Male
Middle Aged
Proctocolectomy, Restorative
Retrospective Studies
Risk Factors
Single-Cell Analysis
Transcriptome
Young Adult

authors with profiles

John Cursio
Le Shen
Christopher Weber
Andrea Olivas
Eugene Chang
David Rubin
Kinga Olortegui
David Zemmour
Junjie Xing
Konstantin Umanskiy