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Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
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Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104). J Transl Med. 2012 Dec 10; 10:246.
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subject areas
Adult
Aged
Aged, 80 and over
Biopsy
Cell Line, Tumor
Enzyme Inhibitors
Extracellular Signal-Regulated MAP Kinases
Farnesyltranstransferase
Female
HSP40 Heat-Shock Proteins
Humans
Interferon-gamma
Male
Melanoma
Middle Aged
Neoplasm Staging
Phosphorylation
Proto-Oncogene Proteins c-akt
Quinolones
Signal Transduction
Skin Neoplasms
T-Lymphocytes
Treatment Outcome
authors with profiles
Thomas Gajewski