"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
|
| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
|
| Concept/Terms |
Interferon-gamma- Interferon-gamma
- gamma-Interferon
- Interferon, Immune
- Immune Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, gamma
|
Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 3 | 5 |
| 1997 | 2 | 4 | 6 |
| 1998 | 5 | 5 | 10 |
| 1999 | 2 | 6 | 8 |
| 2000 | 4 | 4 | 8 |
| 2001 | 7 | 6 | 13 |
| 2002 | 4 | 9 | 13 |
| 2003 | 4 | 13 | 17 |
| 2004 | 6 | 19 | 25 |
| 2005 | 5 | 9 | 14 |
| 2006 | 4 | 10 | 14 |
| 2007 | 4 | 14 | 18 |
| 2008 | 7 | 14 | 21 |
| 2009 | 2 | 10 | 12 |
| 2010 | 1 | 13 | 14 |
| 2011 | 8 | 8 | 16 |
| 2012 | 1 | 13 | 14 |
| 2013 | 1 | 9 | 10 |
| 2014 | 2 | 8 | 10 |
| 2015 | 2 | 8 | 10 |
| 2016 | 2 | 6 | 8 |
| 2017 | 1 | 6 | 7 |
| 2018 | 1 | 4 | 5 |
| 2019 | 3 | 4 | 7 |
| 2020 | 3 | 8 | 11 |
| 2021 | 2 | 3 | 5 |
| 2022 | 0 | 3 | 3 |
| 2023 | 2 | 3 | 5 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 3 | 4 |
| 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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m6A RNA methylation modulates IFN-?-stimulated intestinal epithelial cell-intrinsic antiparasitic defense. PLoS Pathog. 2026 07; 22(7):e1014442.
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Aberrant STAT signaling and T cell dysregulation define a targetable pediatric sepsis endotype. J Clin Invest. 2026 Jul 15; 136(14).
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Inflammation-Induced Claudin-2 Up-Regulation Limits Pancreatitis Development by Enhancing Pancreatic Ductal Transport. Gastroenterology. 2026 Oct; 171(4):699-716.
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Immunogenicity and efficacy over 12 months following a fourth dose of a bivalent mRNA or protein-based COVID-19 vaccine: A randomised controlled trial in Australia. J Infect. 2026 Apr; 92(4):106727.
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Phase II Trial of Interleukin-12 Followed by Interferon Alfa-2b in Patients with Metastatic Malignant Melanoma: Results from CALGB 500001 (Alliance). Cancer Immunol Res. 2026 Mar 04; 14(3):423-433.
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Hyporesponsive fetus-specific T cell responses in multiparous human pregnancy. Front Immunol. 2025; 16:1634430.
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Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation. Nature. 2025 07; 643(8071):509-518.
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IFN-?-resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models. Sci Transl Med. 2025 06 04; 17(801):eadp8166.
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection. Cell. 2025 Jun 12; 188(12):3135-3151.e22.
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Poly I:C vaccination drives transient CXCL9 expression near B cell follicles in the lymph node through type-I and type-II interferon signaling. Cytokine. 2024 11; 183:156731.