"Aminopterin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A folic acid derivative used as a rodenticide that has been shown to be teratogenic.
| Descriptor ID |
D000630
|
| MeSH Number(s) |
D03.633.100.733.631.192
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aminopterin".
Below are MeSH descriptors whose meaning is more specific than "Aminopterin".
This graph shows the total number of publications written about "Aminopterin" by people in this website by year, and whether "Aminopterin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aminopterin" by people in Profiles.
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Randomized phase 2b study of pralatrexate versus erlotinib in patients with stage IIIB/IV non-small-cell lung cancer (NSCLC) after failure of prior platinum-based therapy. J Thorac Oncol. 2012 Jun; 7(6):1041-8.
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Pralatrexate with vitamin supplementation in patients with previously treated, advanced non-small cell lung cancer: safety and efficacy in a phase 1 trial. J Thorac Oncol. 2011 Nov; 6(11):1915-22.
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Phase II trial of oral aminopterin for adults and children with refractory acute leukemia. Clin Cancer Res. 2005 Nov 15; 11(22):8089-96.
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Edatrexate (10-ethyl-deaza-aminopterin) (NSC #626715) with or without leucovorin rescue for malignant mesothelioma. Sequential phase II trials by the cancer and leukemia group B. Cancer. 1999 Nov 15; 86(10):1985-91.
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Antifolates: the next generation. Semin Oncol. 1992 Dec; 19(6):707-19.
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Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity. J Biol Chem. 1992 Mar 05; 267(7):4317-21.