"alpha-MSH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
Descriptor ID |
D000521
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MeSH Number(s) |
D06.472.699.327.935.179 D06.472.699.327.935.531.750.050 D06.472.699.631.525.600.179 D06.472.699.631.525.600.531.750.050 D12.644.400.400.935.179 D12.644.400.400.935.531.750.050 D12.644.400.460.050 D12.644.548.365.935.179 D12.644.548.365.935.531.750.050 D12.644.548.691.525.690.179 D12.644.548.691.525.690.531.750.050 D12.776.631.650.405.935.179 D12.776.631.650.405.935.531.750.050 D12.776.631.650.460.050
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Concept/Terms |
alpha-MSH- alpha-MSH
- alpha MSH
- alpha-Melanotropin
- alpha Melanotropin
- Acetylated ACTH (1-13)NH2
- alpha-Melanocyte-Stimulating Hormone
- Hormone, alpha-Melanocyte-Stimulating
- alpha Melanocyte Stimulating Hormone
- MSH, alpha
ACTH (1-13)NH2- ACTH (1-13)NH2
- (Desacetyl)alpha-MSH
- DE-alpha-MSH
- MSH, (Desacetyl)alpha-
- Des-Acetyl MSH
- MSH, Des-Acetyl
- Desacetyl alpha-MSH
- Desacetyl alpha MSH
- alpha-MSH, Desacetyl
- Desacetyl alpha-Melanocyte-Stimulating Hormone
- Desacetyl alpha Melanocyte Stimulating Hormone
- Hormone, Desacetyl alpha-Melanocyte-Stimulating
- alpha-Melanocyte-Stimulating Hormone, Desacetyl
- (Des-Acetyl)-alpha-MSH
- Adrenocorticotropin (1-13)NH2
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Below are MeSH descriptors whose meaning is more general than "alpha-MSH".
Below are MeSH descriptors whose meaning is more specific than "alpha-MSH".
This graph shows the total number of publications written about "alpha-MSH" by people in this website by year, and whether "alpha-MSH" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "alpha-MSH" by people in Profiles.
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A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake. Am J Physiol Regul Integr Comp Physiol. 2010 Mar; 298(3):R720-8.
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The dynamic properties of intermediate filaments during organelle transport. J Cell Sci. 2009 Aug 15; 122(Pt 16):2914-23.
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AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality. Kidney Int. 2008 Jun; 73(11):1266-74.
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Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature. 2001 Oct 25; 413(6858):794-5.
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Structure and function of ASP, the human homolog of the mouse agouti gene. Hum Mol Genet. 1995 Feb; 4(2):223-30.