"Chlorzoxazone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
| Descriptor ID |
D002753
|
| MeSH Number(s) |
D03.633.100.221.346
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Chlorzoxazone".
Below are MeSH descriptors whose meaning is more specific than "Chlorzoxazone".
This graph shows the total number of publications written about "Chlorzoxazone" by people in this website by year, and whether "Chlorzoxazone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chlorzoxazone" by people in Profiles.
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Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6023-6034.
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Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds. J Pharmacol Exp Ther. 2001 Mar; 296(3):683-9.
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Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6-hydroxylation. Clin Pharmacol Ther. 1998 Mar; 63(3):296-302.