DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia. Cancer Discov. 2016 05; 6(5):501-15.

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subject areas

Animals
Biopsy
Bone Marrow
Cell Transformation, Neoplastic
Cluster Analysis
Disease Models, Animal
Disease Progression
DNA (Cytosine-5-)-Methyltransferases
DNA Methylation
fms-Like Tyrosine Kinase 3
Gene Expression Profiling
Gene Expression Regulation
Genetic Loci
Genotype
Haploinsufficiency
High-Throughput Nucleotide Sequencing
Humans
Karyotype
Leukemia, Myeloid, Acute
Mice
Mice, Transgenic
Mutation
Myeloproliferative Disorders
Penetrance
Tandem Repeat Sequences

authors with profiles

Michelle M. Lebeau