"Debrisoquin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Descriptor ID |
D003647
|
| MeSH Number(s) |
D03.633.100.531.205
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Debrisoquin".
Below are MeSH descriptors whose meaning is more specific than "Debrisoquin".
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Below are the most recent publications written about "Debrisoquin" by people in Profiles.
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Assessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis. Clin Pharmacol Ther. 1989 Mar; 45(3):328-33.