"Nomifensine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
| Descriptor ID |
D009627
|
| MeSH Number(s) |
D03.633.100.531.535
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nomifensine".
Below are MeSH descriptors whose meaning is more specific than "Nomifensine".
This graph shows the total number of publications written about "Nomifensine" by people in this website by year, and whether "Nomifensine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nomifensine" by people in Profiles.
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Monitoring Dopamine Responses to Potassium Ion and Nomifensine by in Vivo Microdialysis with Online Liquid Chromatography at One-Minute Resolution. ACS Chem Neurosci. 2017 02 15; 8(2):329-338.
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In Vivo Monitoring of Dopamine by Microdialysis with 1 min Temporal Resolution Using Online Capillary Liquid Chromatography with Electrochemical Detection. Anal Chem. 2015 Jun 16; 87(12):6088-94.
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Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants. Eur J Pharmacol. 2007 Jul 30; 568(1-3):112-23.