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Alfred Heller

TitleEmeritus/Emerita, Professor
InstitutionUniversity of Chicago
DepartmentPhysiology & Pharmacology
AddressChicago IL 60637
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    R01DA009764     (HELLER, ALFRED)Jul 5, 1996 - Apr 30, 2001
    NIH
    MONOAMINE DEVELOPMENT FOLLOWING IN UTERO DRUG EXPOSURE
    Role: Principal Investigator
    R37MH042134     (HELLER, ALFRED)Dec 1, 1986 - Jan 31, 1996
    NIH
    NEUROTOXICITY OF PSYCHOTROPIC DRUGS
    Role: Principal Investigator
    R01MH028942     (HELLER, ALFRED)Sep 1, 1977 - Jul 31, 2000
    NIH
    DRUG MECHANISM IN NEURONAL DOPAMINE ORGANIZATION
    Role: Principal Investigator
    T32GM007151     (MILLER, RICHARD J)Jul 1, 1975 - Jun 30, 2001
    NIH
    PHARMACOLOGICAL SCIENCES TRAINING PROGRAM
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Heller A, Won L, Bubula N, Hessefort S, Kurutz JW, Reddy GA, Gross M. Long-chain fatty acids increase cellular dopamine in an immortalized cell line (MN9D) derived from mouse mesencephalon. Neurosci Lett. 2005 Mar 07; 376(1):35-9. PMID: 15694270.
      Citations: 4     Fields:    Translation:AnimalsCells
    2. Won L, Bubula N, Hessefort S, Gross M, Heller A. Enhanced survival of primary murine dopaminergic neurons induced by a partially purified cell lysate fraction from mouse-derived striatal hybrid monoclonal cells. Neurosci Lett. 2003 Dec 19; 353(2):83-6. PMID: 14664906.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. Won L, Bubula N, Heller A. Fetal exposure to (+/-)-methylenedioxymethamphetamine in utero enhances the development and metabolism of serotonergic neurons in three-dimensional reaggregate tissue culture. Brain Res Dev Brain Res. 2002 Jul 30; 137(1):67-73. PMID: 12128255.
      Citations: 6     Fields:    Translation:AnimalsCells
    4. Won L, Bubula N, Heller A. Fetal exposure to methamphetamine in utero stimulates development of serotonergic neurons in three-dimensional reaggregate tissue culture. Synapse. 2002 Feb; 43(2):139-44. PMID: 11754494.
      Citations: 4     Fields:    Translation:AnimalsCells
    5. Heller A, Bubula N, Freeney A, Won L. Elevation of fetal dopamine following exposure to methamphetamine in utero. Brain Res Dev Brain Res. 2001 Sep 23; 130(1):139-42. PMID: 11557103.
      Citations: 8     Fields:    Translation:Animals
    6. Heller A, Bubula N, Lew R, Heller B, Won L. Gender-dependent enhanced adult neurotoxic response to methamphetamine following fetal exposure to the drug. J Pharmacol Exp Ther. 2001 Aug; 298(2):769-79. PMID: 11454941.
      Citations: 5     Fields:    Translation:Animals
    7. Won L, Bubula N, McCoy H, Heller A, Won L, Bubula N, McCoy H, Heller A. Methamphetamine concentrations in fetal and maternal brain following prenatal exposure. Neurotoxicol Teratol. 2001 Jul-Aug; 23(4):349-54. PMID: 11485837.
      Citations: 17     Fields:    Translation:Animals
    8. Heller B, Schweingruber F, Guvenc D, Heller A. Computer experiments to determine whether over- or under-counting necessarily affects the determination of difference in cell number between experimental groups. J Neurosci Methods. 2001 Mar 30; 106(1):91-9. PMID: 11248344.
      Citations: 1     Fields:    Translation:Animals
    9. Heller A, Freeney A, Hessefort S, Villereal M, Won L. Cellular dopamine is increased following exposure to a factor derived from immortalized striatal neurons [corrected]. Neurosci Lett. 2000 Dec 01; 295(1-2):1-4. PMID: 11078922.
      Citations: 1     Fields:    Translation:HumansCells
    10. Nakamura K, Won L, Heller A, Kang UJ. Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system. Brain Res. 2000 Aug 11; 873(2):203-11. PMID: 10930545.
      Citations: 1     Fields:    Translation:AnimalsCells
    11. Harkins AB, Dlouhy S, Ghetti B, Cahill AL, Won L, Heller B, Heller A, Fox AP. Evidence of elevated intracellular calcium levels in weaver homozygote mice. J Physiol. 2000 Apr 15; 524 Pt 2:447-55. PMID: 10766925; PMCID: PMC2269872.
      Citations: 4     Fields:    Translation:AnimalsCells
    12. Fox AP, Dlouhy S, Ghetti B, Hurley JH, Nucifora PG, Nelson DJ, Won L, Heller A. Altered responses to potassium in cerebellar neurons from weaver heterozygote mice. Exp Brain Res. 1998 Dec; 123(3):298-306. PMID: 9860268.
      Citations: 4     Fields:    Translation:AnimalsCells
    13. Heller A, Choi H, Won L. Regulation of developing dopaminergic axonal arbor size in three-dimensional reaggregate tissue culture. J Comp Neurol. 1997 Aug 04; 384(3):349-58. PMID: 9254032.
      Citations:    Fields:    Translation:AnimalsCells
    14. Won L, Ghetti B, Heller B, Heller A. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Exp Brain Res. 1997 Jun; 115(1):174-9. PMID: 9224846.
      Citations: 4     Fields:    Translation:AnimalsCells
    15. Heller A, Price S, Won L. Glial-derived neurotrophic factor (GDNF) induced morphological differentiation of an immortalized monoclonal hybrid dopaminergic cell line of mesencephalic neuronal origin. Brain Res. 1996 Jun 24; 725(1):132-6. PMID: 8828597.
      Citations: 8     Fields:    Translation:AnimalsCells
    16. Heller A, Won L, Heller B, Hoffmann PC. Examination of developmental neurotoxicity by the use of tissue culture model systems. Clin Exp Pharmacol Physiol. 1995 May; 22(5):375-8. PMID: 7554436.
      Citations:    Fields:    Translation:HumansCells
    17. Wainwright MS, Perry BD, Won LA, O'Malley KL, Wang WY, Ehrlich ME, Heller A. Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties. J Neurosci. 1995 Jan; 15(1 Pt 2):676-88. PMID: 7823171; PMCID: PMC6578282.
      Citations: 11     Fields:    Translation:AnimalsCells
    18. Vidal L, Heller B, Won L, Heller A. Quantitation of dopaminergic neurons in 3-dimensional reaggregate tissue culture by computer-assisted image analysis. J Neurosci Methods. 1995 Jan; 56(1):89-98. PMID: 7715250.
      Citations:    Fields:    Translation:AnimalsCells
    19. Choi HK, Won L, Heller A. Dopaminergic neurons grown in three-dimensional reaggregate culture for periods of up to one year. J Neurosci Methods. 1993 Mar; 46(3):233-44. PMID: 8097798.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Choi HK, Won L, Roback JD, Wainer BH, Heller A. Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. Proc Natl Acad Sci U S A. 1992 Oct 01; 89(19):8943-7. PMID: 1357658; PMCID: PMC50040.
      Citations: 41     Fields:    Translation:AnimalsCells
    21. Won L, Kontur PJ, Choi HK, Hoffmann PC, Heller B, Heller A. Acute and persistent effects of methamphetamine on developing monoaminergic neurons in reaggregate tissue culture. Brain Res. 1992 Mar 13; 575(1):6-12. PMID: 1504781.
      Citations: 1     Fields:    Translation:AnimalsCells
    22. Kontur PJ, Won LA, Hoffmann PC, Heller A. Survival of developing dopaminergic neurons in reaggregate tissue culture following treatment with methamphetamine. Neurosci Lett. 1991 Aug 19; 129(2):254-8. PMID: 1684029.
      Citations: 1     Fields:    Translation:AnimalsCells
    23. Choi HK, Won LA, Kontur PJ, Hammond DN, Fox AP, Wainer BH, Hoffmann PC, Heller A. Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion. Brain Res. 1991 Jun 21; 552(1):67-76. PMID: 1913182.
      Citations: 81     Fields:    Translation:AnimalsCells
    24. Won L, Price S, Wainer BH, Hoffmann PC, Bolam JP, Greengard P, Heller A. Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP-32-containing cells in three-dimensional reaggregate tissue culture. J Comp Neurol. 1989 Nov 01; 289(1):165-77. PMID: 2572612.
      Citations: 2     Fields:    Translation:AnimalsCells
    25. Won L, Heller A, Hoffmann PC. Selective association of dopamine axons with their striatal target cells in vitro. Brain Res Dev Brain Res. 1989 May 01; 47(1):93-100. PMID: 2736769.
      Citations: 1     Fields:    Translation:AnimalsCells
    26. Hsiang J, Heller A, Hoffmann PC, Mobley WC, Wainer BH. The effects of nerve growth factor on the development of septal cholinergic neurons in reaggregate cell cultures. Neuroscience. 1989; 29(1):209-23. PMID: 2710345.
      Citations: 2     Fields:    Translation:AnimalsCells
    27. Heller A, Kontur P, Hoffmann P, Heller B. Quantitation of neurochemically identified neurons in reaggregate tissue cultures. J Neurosci Methods. 1988 Aug; 25(1):83-90. PMID: 3221689.
      Citations: 1     Fields:    Translation:AnimalsCells
    28. Hsiang J, Price SD, Heller A, Hoffmann PC, Wainer BH. Ultrastructural evidence for hippocampal target cell-mediated trophic effects on septal cholinergic neurons in reaggregating cell cultures. Neuroscience. 1988 Aug; 26(2):417-31. PMID: 3173683.
      Citations:    Fields:    Translation:AnimalsCells
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