"Histamine H2 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
| Descriptor ID |
D006635
|
| MeSH Number(s) |
D27.505.519.625.375.425.425 D27.505.696.577.375.425.425
|
| Concept/Terms |
Histamine H2 Antagonists- Histamine H2 Antagonists
- Receptor Blockaders, H2
- Blockaders, Histamine H2 Receptor
- Histamine H2 Receptor Blockaders
- Histamine H2 Blockers
- Blockers, Histamine H2
- H2 Blockers, Histamine
- Receptor Antagonists, Histamine H2
- Histamine H2 Receptor Antagonists
- Antagonists, Histamine H2
- H2 Antagonists, Histamine
- H2 Receptor Blockaders
- Blockaders, H2 Receptor
- Antihistaminics, H2
- H2 Antihistaminics
|
Below are MeSH descriptors whose meaning is more general than "Histamine H2 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H2 Antagonists".
This graph shows the total number of publications written about "Histamine H2 Antagonists" by people in this website by year, and whether "Histamine H2 Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histamine H2 Antagonists" by people in Profiles.
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Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis. Am J Med. 2022 10; 135(10):1231-1243.e8.
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Fundoplication. Clin Perinatol. 2017 12; 44(4):795-803.
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Challenging surgical dogma in the management of proximal esophageal atresia with distal tracheoesophageal fistula: Outcomes from the Midwest Pediatric Surgery Consortium. J Pediatr Surg. 2018 Jul; 53(7):1267-1272.
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Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis. Dis Esophagus. 2017 May 01; 30(5):1-9.
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Alginate therapy is effective treatment for gastroesophageal reflux disease symptoms: a systematic review and meta-analysis. Dis Esophagus. 2017 02 01; 30(2):1-8.
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Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia. Neurobiol Dis. 2015 Apr; 76:67-76.
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Valuable heartburn data that may be difficult to swallow. Surg Obes Relat Dis. 2015 Jan-Feb; 11(1):229.
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Laryngopharyngeal reflux: paradigms for evaluation, diagnosis, and treatment. Ann Otol Rhinol Laryngol. 2014 Oct; 123(10):677-85.
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Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials. Lancet Respir Med. 2013 Jul; 1(5):369-76.
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Proton-pump inhibitor use is associated with low serum magnesium concentrations. Kidney Int. 2013 Apr; 83(4):692-9.