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Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.
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Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.
Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct; 48(10):973-983.
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PubMed
subject areas
Cell Line, Tumor
Cytochrome P-450 CYP3A
Cytochrome P-450 CYP3A Inhibitors
Glucuronides
Humans
Ketoconazole
Kinetics
Megestrol Acetate
Metabolome
Microsomes, Liver
Oxidation-Reduction
Prostate-Specific Antigen
Proton Magnetic Resonance Spectroscopy
Receptors, Cytoplasmic and Nuclear
Recombinant Proteins
Substrate Specificity
Troleandomycin
authors with profiles
Suzanne D. Conzen
Geoffrey Greene
Mark J. Ratain