Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statins.

Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statins. J Am Coll Cardiol. 2012 Nov 06; 60(19):1888-98.

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subject areas

Adult
Antibodies, Monoclonal
Cholesterol, LDL
Cohort Studies
Dose-Response Relationship, Drug
Double-Blind Method
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypercholesterolemia
Male
Proprotein Convertase 9
Proprotein Convertases
Receptors, LDL
Serine Endopeptidases
Treatment Outcome
Young Adult