"Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
| Descriptor ID |
D009857
|
| MeSH Number(s) |
G05.360.340.024.340.375.500
|
| Concept/Terms |
Oncogenes- Oncogenes
- Transforming Genes
- Transforming Gene
- Gene, Transforming
- Genes, Transforming
- Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Oncogenes".
This graph shows the total number of publications written about "Oncogenes" by people in this website by year, and whether "Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 2 | 1 | 3 |
| 1997 | 2 | 0 | 2 |
| 1998 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 1 | 2 |
| 2007 | 2 | 4 | 6 |
| 2010 | 1 | 2 | 3 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 2 | 3 |
| 2014 | 0 | 3 | 3 |
| 2015 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 3 | 5 |
| 2019 | 3 | 0 | 3 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oncogenes" by people in Profiles.
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HYENA detects oncogenes activated by distal enhancers in cancer. Nucleic Acids Res. 2024 Sep 09; 52(16):e77.
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SFyNCS detects oncogenic fusions involving non-coding sequences in cancer. Nucleic Acids Res. 2023 Oct 13; 51(18):e96.
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Pan-cancer assessment of mutational landscape in intrinsically disordered hotspots reveals potential driver genes. Nucleic Acids Res. 2022 05 20; 50(9):e49.
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Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia. Front Immunol. 2022; 13:845488.
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Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity. Blood. 2021 10 07; 138(14):1225-1236.
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The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma. Cancer. 2021 02 15; 127(4):544-553.
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Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types. Genome Med. 2020 10 27; 12(1):90.
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KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi's sarcoma. PLoS Pathog. 2020 10; 16(10):e1009006.
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Pan-cancer analysis of whole genomes. Nature. 2020 02; 578(7793):82-93.
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Detailed modeling of positive selection improves detection of cancer driver genes. Nat Commun. 2019 07 30; 10(1):3399.