"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
| Descriptor ID |
D011519
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".
- Proto-Oncogenes
- Genes, abl
- Genes, bcl-1
- Genes, bcl-2
- Genes, erbA
- Genes, erbB
- Genes, fms
- Genes, fos
- Genes, jun
- Genes, mos
- Genes, myb
- Genes, myc
- Genes, ras
- Genes, rel
- Genes, sis
- Genes, src
This graph shows the total number of publications written about "Proto-Oncogenes" by people in this website by year, and whether "Proto-Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 4 | 1 | 5 |
| 1995 | 4 | 0 | 4 |
| 1996 | 2 | 0 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 3 | 0 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition. Oncogene. 2017 05 11; 36(19):2737-2749.
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miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):11511-6.
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Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5594-9.
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miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm Bowel Dis. 2012 Jan; 18(1):94-100.
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010 Dec 14; 18(6):553-67.
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Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res. 2008 Sep; 466(9):2114-30.
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The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions. Mol Endocrinol. 2005 May; 19(5):1158-69.
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Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16). Genes Chromosomes Cancer. 2004 Nov; 41(3):257-65.
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EVI1 abrogates interferon-alpha response by selectively blocking PML induction. J Biol Chem. 2005 Jan 07; 280(1):428-36.
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Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangements. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7853-8.