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Downregulation of RUNX1/CBFß by MLL fusion proteins enhances hematopoietic stem cell self-renewal.
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Downregulation of RUNX1/CBFß by MLL fusion proteins enhances hematopoietic stem cell self-renewal.
Downregulation of RUNX1/CBFß by MLL fusion proteins enhances hematopoietic stem cell self-renewal. Blood. 2014 Mar 13; 123(11):1729-38.
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PubMed
subject areas
Animals
Blotting, Western
Bone Marrow Transplantation
Core Binding Factor Alpha 2 Subunit
Core Binding Factor beta Subunit
Flow Cytometry
Hematopoietic Stem Cells
Humans
Leukemia, Myeloid, Acute
Mice
Mice, Inbred C57BL
Myeloid-Lymphoid Leukemia Protein
Oncogene Proteins, Fusion
Phenotype
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Translocation, Genetic