"Formyltetrahydrofolates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-Formyltetrahydrofolate is leukovorin (citrovorum factor) while N(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions.
| Descriptor ID |
D005575
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| MeSH Number(s) |
D03.633.100.733.631.400.800.350 D08.211.840.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Formyltetrahydrofolates".
Below are MeSH descriptors whose meaning is more specific than "Formyltetrahydrofolates".
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Below are the most recent publications written about "Formyltetrahydrofolates" by people in Profiles.
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Inhibition of thymidylate synthase by the diastereoisomers of leucovorin. Cancer Chemother Pharmacol. 1990; 26(4):273-7.