Immunoglobulin Light Chains
"Immunoglobulin Light Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polypeptide chains, consisting of 211 to 217 amino acid residues and having a molecular weight of approximately 22 kDa. There are two major types of light chains, kappa and lambda. Two Ig light chains and two Ig heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) make one immunoglobulin molecule.
| Descriptor ID |
D007147
|
| MeSH Number(s) |
D12.776.124.486.485.705.750 D12.776.124.790.651.705.750 D12.776.377.715.548.705.750
|
| Concept/Terms |
Immunoglobulin Light Chains- Immunoglobulin Light Chains
- Chains, Immunoglobulin Light
- Light Chains, Immunoglobulin
- Immunoglobulin Light-Chain
- Light-Chain, Immunoglobulin
- Light-Chain Immunoglobulins
- Light Chain Immunoglobulins
- Immunoglobulin Light Chain
- Light Chain, Immunoglobulin
- Immunoglobulins, Light-Chain
- Immunoglobulins, Light Chain
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light Chains".
This graph shows the total number of publications written about "Immunoglobulin Light Chains" by people in this website by year, and whether "Immunoglobulin Light Chains" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 3 | 0 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2023 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin Light Chains" by people in Profiles.
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Perivascular Amyloid Deposition in Immunoglobulin Light Chain Cardiac Amyloidosis and Its Implications on Echocardiographic Cardiac Remodeling. J Am Soc Echocardiogr. 2024 Oct; 37(10):1010-1012.
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Vascular Amyloid Deposition Is Highly Prevalent in Immunoglobulin Light Chain Cardiac Amyloidosis. JACC Cardiovasc Imaging. 2023 08; 16(8):1121-1123.
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Chronic Lymphocytic Leukemia With Two B-Cell Populations of Discordant Light Chain Restrictions in Individual Patients: Parallel Development of Biclonal B-Cell Neoplasms or Clonal Evolution With Isotype Switch? Am J Clin Pathol. 2023 04 04; 159(4):337-351.
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Novel Cardiovascular Magnetic Resonance Model to Distinguish Immunoglobulin Light Chain From Transthyretin Cardiac Amyloidosis. JACC Cardiovasc Imaging. 2021 01; 14(1):302-304.
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819.
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Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry. MAbs. 2019 Nov-Dec; 11(8):1351-1357.
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An Efficient Method to Generate Monoclonal Antibodies from Human B Cells. Methods Mol Biol. 2019; 1904:109-145.
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Surface Light Chain Expression in Primary Mediastinal Large B-Cell Lymphomas by Multiparameter Flow Cytometry. Am J Clin Pathol. 2015 Oct; 144(4):635-41.
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Serum free light chain reduction correlates with response and progression-free survival following carfilzomib therapy in relapsed/refractory multiple myeloma. Leuk Lymphoma. 2015; 56(10):2959-61.
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Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells. Nat Commun. 2014 Jun 09; 5:4041.