"Porphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
| Descriptor ID |
D011166
|
| MeSH Number(s) |
D03.383.129.578.840.500 D03.633.400.909.500 D04.345.783.500 D23.767.727
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Porphyrins".
Below are MeSH descriptors whose meaning is more specific than "Porphyrins".
This graph shows the total number of publications written about "Porphyrins" by people in this website by year, and whether "Porphyrins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 2 | 0 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Porphyrins" by people in Profiles.
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Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer. J Med Chem. 2021 01 14; 64(1):741-767.
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Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy. J Am Chem Soc. 2016 09 28; 138(38):12502-10.
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The role of strong hypoxia in tumors after treatment in the outcome of bacteriochlorin-based photodynamic therapy. Free Radic Biol Med. 2014 Aug; 73:239-51.
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Intraoperative fluorescence-guided resection of high-grade malignant gliomas using 5-aminolevulinic acid-induced porphyrins: a systematic review and meta-analysis of prospective studies. PLoS One. 2013; 8(5):e63682.
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Biomodulatory approaches to photodynamic therapy for solid tumors. Cancer Lett. 2012 Dec 29; 326(1):8-16.
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension. Adv Exp Med Biol. 2010; 661:171-85.
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Porphyrin-based photocatalytic nanolithography: a new fabrication tool for protein arrays. Mol Cell Proteomics. 2009 Aug; 8(8):1823-31.
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Confocal scanning laser tomography analysis of choroidal neovascularization and correlation with quantitative fluorescein angiography. Curr Eye Res. 2009 Apr; 34(4):319-27.
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Phototocatalytic lithography of poly(propylene sulfide) block copolymers: toward high-throughput nanolithography for biomolecular arraying applications. Langmuir. 2009 Jan 20; 25(2):1238-44.
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Porphyrin-based photocatalytic lithography. Langmuir. 2008 May 06; 24(9):5179-84.