"Placental Lactogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.
| Descriptor ID |
D010928
|
| MeSH Number(s) |
D06.472.699.649.692 D12.644.548.726.692 D12.776.780.650
|
| Concept/Terms |
Placental Lactogen- Placental Lactogen
- Lactogen, Placental
- Choriomammotropin
- Lactogen Hormone, Placental
- Mammotropic Hormone, Placental
- Placental Mammotropic Hormone
- Pregnancy-Associated Plasma Protein D
- Pregnancy Associated Plasma Protein D
- Placental Luteotropin
- Luteotropin, Placental
- Somatomammotropin, Chorionic
- Chorionic Somatomammotropin
- Choriomammotrophin
- PAPP-D
Human Placental Lactogen- Human Placental Lactogen
- Placental Lactogen, Human
- HCS (Human Chorionic Somatomammotropin)
- HPL (Human Placental Lactogen)
- Chorionic Somatomammotropin, Human
- Human Chorionic Somatomammotropin
|
Below are MeSH descriptors whose meaning is more general than "Placental Lactogen".
Below are MeSH descriptors whose meaning is more specific than "Placental Lactogen".
This graph shows the total number of publications written about "Placental Lactogen" by people in this website by year, and whether "Placental Lactogen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Placental Lactogen" by people in Profiles.
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Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity. Cancer Res. 2017 04 01; 77(7):1684-1696.
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Do placental genes affect maternal breast cancer? Association between offspring's CGB5 and CSH1 gene variants and maternal breast cancer risk. Cancer Res. 2008 Dec 01; 68(23):9729-34.
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Crystal structure and site 1 binding energetics of human placental lactogen. J Mol Biol. 2006 May 05; 358(3):773-84.
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Placental genes and breast cancer: can the offspring's or father's genotypes predict mother's risk? Epidemiology. 2003 Mar; 14(2):251-3.
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Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor. Nat Struct Biol. 2000 Sep; 7(9):808-15.
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Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor. Acta Crystallogr D Biol Crystallogr. 1998 Nov 01; 54(Pt 6 Pt 2):1408-11.
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Tumor associated markers in clinical diagnosis. Ann Clin Lab Sci. 1978 May-Jun; 8(3):167-75.
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Hormone and enzyme levels in normal and complicated pregnancy. Am J Obstet Gynecol. 1973 Aug 15; 116(8):1105-13.
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The degradation of human placental lactogen in normal and nephrectomized dogs. J Endocrinol. 1972 Jun; 53(3):407-17.
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Vaginal mucification induced by pituitary prolactin and placental lactogen in mice. A luteotrophic test for protein hormone preparations. Gynecol Invest. 1970; 1(4):210-21.