"Staphylococcal Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
| Descriptor ID |
D013205
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| MeSH Number(s) |
D12.776.097.820 D23.050.161.821
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Staphylococcal Protein A".
Below are MeSH descriptors whose meaning is more specific than "Staphylococcal Protein A".
This graph shows the total number of publications written about "Staphylococcal Protein A" by people in this website by year, and whether "Staphylococcal Protein A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Staphylococcal Protein A" by people in Profiles.
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A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood. Vaccine. 2023 08 07; 41(35):5079-5084.
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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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A protein A based Staphylococcus aureus vaccine with improved safety. Vaccine. 2021 06 29; 39(29):3907-3915.
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Peptidoglycan Contribution to the B Cell Superantigen Activity of Staphylococcal Protein A. mBio. 2021 04 20; 12(2).
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Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22992-23000.
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Staphylococcus aureus Decolonization of Mice With Monoclonal Antibody Neutralizing Protein A. J Infect Dis. 2019 02 23; 219(6):884-888.
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Septal secretion of protein A in Staphylococcus aureus requires SecA and lipoteichoic acid synthesis. Elife. 2018 05 14; 7.
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Staphylococcal Protein A Contributes to Persistent Colonization of Mice with Staphylococcus aureus. J Bacteriol. 2018 05 01; 200(9).
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A comparison of methods for evaluation of a case of suspected macro-aspartate aminotransferase. Clin Chim Acta. 2016 Dec 01; 463:1-3.
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Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5718-23.