"Staphylococcal Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.
| Descriptor ID |
D013205
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| MeSH Number(s) |
D12.776.097.820 D23.050.161.821
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Staphylococcal Protein A".
Below are MeSH descriptors whose meaning is more specific than "Staphylococcal Protein A".
This graph shows the total number of publications written about "Staphylococcal Protein A" by people in this website by year, and whether "Staphylococcal Protein A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2025 | 3 | 0 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Staphylococcal Protein A" by people in Profiles.
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Examining the role of IgA in a persistent model of Staphylococcus aureus colonization. PLoS Pathog. 2026 Jan; 22(1):e1013924.
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The signal peptide of staphylococcal protein A alters the multimeric states of PepV. Microbiol Spectr. 2025 12 02; 13(12):e0177825.
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A SecA-associated protease modulates the extent of surface display of staphylococcal protein A. J Bacteriol. 2025 04 17; 207(4):e0052224.
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A novel polysaccharide in the envelope of S. aureus influences the septal secretion of preproteins with a YSIRK/GXXS motif. J Bacteriol. 2025 02 20; 207(2):e0047824.
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Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science. 2023 07 28; 381(6656):eadh1720.
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A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood. Vaccine. 2023 08 07; 41(35):5079-5084.
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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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A protein A based Staphylococcus aureus vaccine with improved safety. Vaccine. 2021 06 29; 39(29):3907-3915.
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Peptidoglycan Contribution to the B Cell Superantigen Activity of Staphylococcal Protein A. mBio. 2021 04 20; 12(2).
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Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22992-23000.