"Prostaglandin D2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
| Descriptor ID |
D015230
|
| MeSH Number(s) |
D10.251.355.255.550.200.200 D23.469.050.175.725.200.200
|
| Concept/Terms |
Prostaglandin D2- Prostaglandin D2
- D2, Prostaglandin
- 11-Dehydroprostaglandin F2 alpha
- 11 Dehydroprostaglandin F2 alpha
- F2 alpha, 11-Dehydroprostaglandin
- alpha, 11-Dehydroprostaglandin F2
- PGD2
- 11-Dehydroprostaglandin F2alpha
- 11 Dehydroprostaglandin F2alpha
- F2alpha, 11-Dehydroprostaglandin
|
Below are MeSH descriptors whose meaning is more general than "Prostaglandin D2".
Below are MeSH descriptors whose meaning is more specific than "Prostaglandin D2".
This graph shows the total number of publications written about "Prostaglandin D2" by people in this website by year, and whether "Prostaglandin D2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prostaglandin D2" by people in Profiles.
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DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. Circulation. 2020 02 25; 141(8):655-666.
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Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma. Biochem Biophys Res Commun. 2008 Sep 19; 374(2):231-6.
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Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism. Am J Pathol. 2007 Feb; 170(2):722-32.
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Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. Am J Respir Cell Mol Biol. 2007 May; 36(5):562-72.
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Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor gamma for monocyte recruitment and endothelial regeneration. Eur J Pharmacol. 2005 Jan 31; 508(1-3):255-65.
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Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. Am J Pathol. 2001 Aug; 159(2):591-7.
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Origin of late phase histamine release. J Allergy Clin Immunol. 1996 Oct; 98(4):721-3.
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Unilateral nasal allergen challenge leads to bilateral release of prostaglandin D2. Clin Exp Allergy. 1996 Apr; 26(4):371-8.
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Existence of an enzymatic pathway furnishing arachidonic acid for prostaglandin synthesis from arachidonoyl CoA in rabbit kidney medulla. Biochem Biophys Res Commun. 1994 Jul 29; 202(2):1054-9.
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Effects of antihistamines on inflammatory mediators. Ann Allergy. 1993 Sep; 71(3):292-5.