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Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides.
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Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides.
Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15148-15159.
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PubMed
subject areas
Amino Acid Sequence
Animals
Antibodies
Antigens, Tumor-Associated, Carbohydrate
Cell Line, Tumor
Directed Molecular Evolution
Epitopes
Humans
Mice
Models, Molecular
Mutation
Protein Conformation
T-Lymphocytes
authors with profiles
Hans Schreiber