"HIV Integrase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA.
| Descriptor ID |
D019428
|
| MeSH Number(s) |
D27.505.519.389.375.400 D27.505.954.122.388.077.088.314
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "HIV Integrase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "HIV Integrase Inhibitors".
This graph shows the total number of publications written about "HIV Integrase Inhibitors" by people in this website by year, and whether "HIV Integrase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "HIV Integrase Inhibitors" by people in Profiles.
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Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity. J Med Chem. 2017 06 22; 60(12):5045-5056.
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3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H. J Med Chem. 2016 07 14; 59(13):6136-48.
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LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs. PLoS Pathog. 2012; 8(3):e1002558.
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Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance. Proc Natl Acad Sci U S A. 2011 May 03; 108(18):7613-8.