"Chloramphenicol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Descriptor ID |
D002701
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MeSH Number(s) |
D02.033.455.706.300 D02.455.426.559.389.565.175 D02.640.529.175
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chloramphenicol".
Below are MeSH descriptors whose meaning is more specific than "Chloramphenicol".
This graph shows the total number of publications written about "Chloramphenicol" by people in this website by year, and whether "Chloramphenicol" was a major or minor topic of these publications.
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Below are the most recent publications written about "Chloramphenicol" by people in Profiles.
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Seborrheic dermatitis-like eruption in patients taking isotretinoin therapy for acne: retrospective study of five patients. Am J Clin Dermatol. 2008; 9(4):255-61.
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Trinucleotide repeats affect DNA replication in vivo. Nat Genet. 1997 Nov; 17(3):298-304.
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Mechanisms of action of chloroalanyl antibacterial peptides. Identification of the intracellular enzymes inactivated on treatment of Escherichia coli JSR-O with the dipeptide beta Cl-LAla-beta Cl-LAla. J Biol Chem. 1986 Jun 15; 261(17):7871-8.
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p lambda CM system: observations on the roles of transposable elements in formation and breakdown of plasmids derived from bacteriophage lambda replicons. J Bacteriol. 1983 Feb; 153(2):976-90.
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Bacteriophage N4-induced transcribing activities in Escherichia coli. I. Detection and characterization in cell extracts. Virology. 1979 Jun; 95(2):454-65.
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Fatal aplastic anemia following apparent "dose-related" chloramphenicol toxicity. J Pediatr. 1979 Mar; 94(3):403-6.
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Effect of ampicillin and chloramphenicol alone and in combination on ampicillin-susceptible and -resistant Haemophilus influenzae type B. Antimicrob Agents Chemother. 1979 Mar; 15(3):415-9.
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Transcription and replication of bacteriophage phi6 RNA. Virology. 1978 Aug; 89(1):206-17.
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Chromosomal integration of phage lambda by means of a DNA insertion element. Proc Natl Acad Sci U S A. 1978 Mar; 75(3):1490-4.
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Simplified radioenzymatic assay for chloramphenicol. Antimicrob Agents Chemother. 1978 Jan; 13(1):25-9.