"rac1 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020830
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.700.100.500 D12.644.360.525.700.100.100 D12.776.157.325.515.700.100.100 D12.776.476.525.700.100.100
|
| Concept/Terms |
rac1 GTP-Binding Protein- rac1 GTP-Binding Protein
- GTP-Binding Protein, rac1
- rac1 GTP Binding Protein
- rac1 Protein
- TC-25 GTP-Binding Protein
- GTP-Binding Protein, TC-25
- TC 25 GTP Binding Protein
- ras-Related C3 Botulinum Toxin Substrate 1
- ras Related C3 Botulinum Toxin Substrate 1
|
Below are MeSH descriptors whose meaning is more general than "rac1 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rac1 GTP-Binding Protein".
This graph shows the total number of publications written about "rac1 GTP-Binding Protein" by people in this website by year, and whether "rac1 GTP-Binding Protein" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 1 | 3 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 3 | 4 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 3 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 1 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "rac1 GTP-Binding Protein" by people in Profiles.
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Experimental Lung Injury Reduces Krüppel-like Factor 2 to Increase Endothelial Permeability via Regulation of RAPGEF3-Rac1 Signaling. Am J Respir Crit Care Med. 2017 03 01; 195(5):639-651.
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Contact guidance requires spatial control of leading-edge protrusion. Mol Biol Cell. 2017 Apr 15; 28(8):1043-1053.
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Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells. Oncotarget. 2016 Sep 20; 7(38):61229-61245.
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Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):E6359-68.
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Asef controls vascular endothelial permeability and barrier recovery in the lung. Mol Biol Cell. 2015 Feb 15; 26(4):636-50.
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A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness. Nat Commun. 2014 Sep 16; 5:4858.
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Microtubule dynamics control HGF-induced lung endothelial barrier enhancement. PLoS One. 2014; 9(9):e105912.
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Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism. J Biol Chem. 2014 Feb 21; 289(8):5168-83.
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The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 2013 Aug; 34(24):5958-68.
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Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction. PLoS One. 2013; 8(5):e63007.