"Glycogen Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the degradation of GLYCOGEN in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. This enzyme exists in two forms: an active phosphorylated form ( PHOSPHORYLASE A) and an inactive un-phosphorylated form (PHOSPHORYLASE B). Both a and b forms of phosphorylase exist as homodimers. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver and brain tissue.
| Descriptor ID |
D024981
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| MeSH Number(s) |
D08.811.913.400.450.460.400.186
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Phosphorylase".
This graph shows the total number of publications written about "Glycogen Phosphorylase" by people in this website by year, and whether "Glycogen Phosphorylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycogen Phosphorylase" by people in Profiles.
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Glycogen Repletion in Brown Adipose Tissue upon Refeeding Is Primarily Driven by Phosphorylation-Independent Mechanisms. PLoS One. 2016; 11(5):e0156148.
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Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. Blood. 2012 Nov 15; 120(20):4197-204.
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Transgenic overexpression of protein targeting to glycogen markedly increases adipocytic glycogen storage in mice. Am J Physiol Endocrinol Metab. 2007 Mar; 292(3):E952-63.
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Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E1-8.
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Regulation and function of the muscle glycogen-targeting subunit of protein phosphatase 1 (GM) in human muscle cells depends on the COOH-terminal region and glycogen content. Diabetes. 2003 Sep; 52(9):2221-6.