Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors.

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins. 2004 Jun 01; 55(4):805-13.

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subject areas

Aldehyde Reductase
Binding Sites
Crystallography, X-Ray
Drug Design
Enzyme Inhibitors
Holoenzymes
Imidazoles
Imidazolidines
Imides
Macromolecular Substances
Models, Molecular
Molecular Structure
Quinolones

authors with profiles

Andrzej Joachimiak