Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).

Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16). Cancer Res. 2007 Feb 01; 67(3):992-1000.

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subject areas

Chromosome Inversion
Chromosomes, Human, Pair 6
Core Binding Factor Alpha 2 Subunit
Core Binding Factor beta Subunit
Cyclin-Dependent Kinase Inhibitor p15
DNA Methylation
Gene Silencing
Humans
Leukemia, Myeloid, Acute
Myosin Heavy Chains
Promoter Regions, Genetic
RNA, Neoplasm
Transcriptional Activation

authors with profiles

Michael J. Thirman