"Complement C4b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
| Descriptor ID |
D015935
|
| MeSH Number(s) |
D12.776.124.486.274.350.260
|
| Concept/Terms |
Complement C4b- Complement C4b
- C4b, Complement
- Complement 4b
- Complement Component 4b
- Component 4b, Complement
- C4b Complement
- Complement, C4b
|
Below are MeSH descriptors whose meaning is more general than "Complement C4b".
Below are MeSH descriptors whose meaning is more specific than "Complement C4b".
This graph shows the total number of publications written about "Complement C4b" by people in this website by year, and whether "Complement C4b" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Complement C4b" by people in Profiles.
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Immunoglobulin and Complement Immunohistochemistry on Paraffin Sections in Autoimmune Bullous Diseases: A Systematic Review and Meta-analysis. Am J Dermatopathol. 2021 Oct 01; 43(10):689-699.
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Discordance between immunofluorescence and immunohistochemistry C4d staining and outcomes following heart transplantation. Clin Transplant. 2021 04; 35(4):e14242.
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Routine C4d immunohistochemistry in cardiac allografts: Long-term outcomes. J Heart Lung Transplant. 2017 Dec; 36(12):1329-1335.
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Antibody-mediated rejection in ABO compatible husband to wife living donor liver transplant and review of the literature. Hum Immunol. 2014 Jun; 75(6):578-83.
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Late kidney dysfunction in a kidney transplant recipient. Clin J Am Soc Nephrol. 2014 Mar; 9(3):590-7.
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Plasma cell densities and glomerular filtration rates predict renal allograft outcomes following acute rejection. Transpl Int. 2012 Oct; 25(10):1050-8.
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Anticardiac myosin immunity and chronic allograft vasculopathy in heart transplant recipients. J Immunol. 2011 Jul 15; 187(2):1023-30.
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Thrombotic microangiopathy and peritubular capillary C4d expression in renal allograft biopsies. Clin J Am Soc Nephrol. 2011 Feb; 6(2):395-403.
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Can C4d immunostaining on endomyocardial biopsies be considered a prognostic biomarker in heart transplant recipients? Transplantation. 2010 Oct 15; 90(7):791-8.
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Antibody-mediated rejection of renal allograft in combined liver-kidney transplant. Clin Transplant. 2010 Sep-Oct; 24(5):685-90.