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Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
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Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors.
Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors. Cancer Discov. 2012 May; 2(5):414-24.
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PubMed
subject areas
Adult
Aged
Antineoplastic Agents
Cell Line, Tumor
Drug Resistance, Neoplasm
Exons
Female
HEK293 Cells
Humans
Imidazoles
Indoles
Male
MAP Kinase Kinase 1
Melanoma
Middle Aged
Mutation
Oximes
Proto-Oncogene Proteins B-raf
Sulfonamides
authors with profiles
Richard Koya