Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis.

Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis. Mol Cancer Ther. 2008 Jun; 7(6):1669-79.

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subject areas

Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Bevacizumab
Cell Movement
Cell Proliferation
Cells, Cultured
Drug Synergism
Endothelial Cells
Enzyme Activation
Fluorouracil
Guanine Nucleotide Exchange Factors
Humans
Models, Biological
Naltrexone
Neovascularization, Physiologic
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins pp60(c-src)
Quaternary Ammonium Compounds
Receptor-Like Protein Tyrosine Phosphatases, Class 2
Repressor Proteins
rhoA GTP-Binding Protein
Vascular Endothelial Growth Factor A

authors with profiles

Jonathan Moss