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An APP ectodomain mutation outside of the Aß domain promotes Aß production in vitro and deposition in vivo.
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An APP ectodomain mutation outside of the Aß domain promotes Aß production in vitro and deposition in vivo.
An APP ectodomain mutation outside of the Aß domain promotes Aß production in vitro and deposition in vivo. J Exp Med. 2021 06 07; 218(6).
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PubMed
subject areas
Alzheimer Disease
Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Animals
Brain
Cell Line, Tumor
Disease Models, Animal
Exons
Female
HEK293 Cells
Humans
Male
Mice
Mice, Transgenic
Mutation
Plaque, Amyloid
authors with profiles
Sangram S. Sisodia