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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
Enhanced nicotinic receptor function and drug abuse vulnerability.
Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt.
Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
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Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure. J Mol Med (Berl). 2010 Oct; 88(10):1011-20.
View in:
PubMed
subject areas
Adaptation, Physiological
Animals
Fatty Acids
Glucose
Heart Failure
Humans
Hypertrophy, Right Ventricular
Mitochondria
Oxidation-Reduction
Oxygen
authors with profiles
Lin Piao
Stephen Archer