Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.

Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo. Cancer Res. 2009 Apr 15; 69(8):3689-94.

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subject areas

Animals
Cell Transformation, Neoplastic
Enzyme Activation
Epithelial Cells
Extracellular Signal-Regulated MAP Kinases
MAP Kinase Signaling System
Mice
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins p21(ras)
Thyroid Gland
Thyroid Neoplasms

authors with profiles

Samuel Refetoff