"Lewy Bodies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.
| Descriptor ID |
D016631
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| MeSH Number(s) |
A08.675.460 A11.284.420.460 A11.671.460
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lewy Bodies".
Below are MeSH descriptors whose meaning is more specific than "Lewy Bodies".
This graph shows the total number of publications written about "Lewy Bodies" by people in this website by year, and whether "Lewy Bodies" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lewy Bodies" by people in Profiles.
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CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6.
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Incidental Lewy body disease: do some cases represent a preclinical stage of dementia with Lewy bodies? Neurobiol Aging. 2011 May; 32(5):857-63.
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Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study. Arch Neurol. 2005 Jun; 62(6):1004-7.
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Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol. 2000 Jun; 99(6):663-72.
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Hereditary form of parkinsonism--dementia. Ann Neurol. 1998 Jun; 43(6):768-81.
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Exclusion of genetic linkage to 4q21-23 and 17q21 in a family with Lewy body parkinsonism. Am J Med Genet. 1998 Mar 28; 81(2):166-71.