"Vaccines, Conjugate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
| Descriptor ID |
D018074
|
| MeSH Number(s) |
D20.215.894.865.900 D23.050.865.900
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vaccines, Conjugate".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, Conjugate".
This graph shows the total number of publications written about "Vaccines, Conjugate" by people in this website by year, and whether "Vaccines, Conjugate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Vaccines, Conjugate" by people in Profiles.
-
A Phase 3, Randomized, Double-Blind, Comparator-Controlled Study to Evaluate Safety, Tolerability, and Immunogenicity of V114, a 15-Valent Pneumococcal Conjugate Vaccine, in Allogeneic Hematopoietic Cell Transplant Recipients (PNEU-STEM). Clin Infect Dis. 2023 10 13; 77(8):1102-1110.
-
Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8+ T-cell response. Sci Rep. 2021 03 18; 11(1):6267.
-
Structural and immunological characterization of E. coli derived recombinant CRM197 protein used as carrier in conjugate vaccines. Biosci Rep. 2018 10 31; 38(5).
-
Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection. Hum Vaccin Immunother. 2017 07 03; 13(7):1609-1614.
-
Staphylococcus aureus vaccines: Deviating from the carol. J Exp Med. 2016 08 22; 213(9):1645-53.
-
Sortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracis. Vaccine. 2012 May 14; 30(23):3435-44.
-
Magnitude of interference after diphtheria-tetanus toxoids-acellular pertussis/Haemophilus influenzae type b capsular polysaccharide-tetanus vaccination is related to the number of doses administered. J Infect Dis. 2001 Nov 15; 184(10):1293-9.
-
Pneumococcal vaccines for children: an update. Pediatr Infect Dis J. 1998 Sep; 17(9):823-4.
-
Vaccine antigen interactions after a combination diphtheria-tetanus toxoid-acellular pertussis/purified capsular polysaccharide of Haemophilus influenzae type b-tetanus toxoid vaccine in two-, four- and six-month-old infants. Pediatr Infect Dis J. 1997 Sep; 16(9):863-70.
-
Infant immunization with pneumococcal CRM197 vaccines: effect of saccharide size on immunogenicity and interactions with simultaneously administered vaccines. J Infect Dis. 1997 Aug; 176(2):445-55.