"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
| Descriptor ID |
D017353
|
| MeSH Number(s) |
G05.365.590.762.320 G05.558.800.320
|
| Concept/Terms |
Gene Deletion- Gene Deletion
- Deletion, Gene
- Deletions, Gene
- Gene Deletions
|
Below are MeSH descriptors whose meaning is more general than "Gene Deletion".
Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".
This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 2 | 6 |
| 1997 | 4 | 3 | 7 |
| 1998 | 1 | 3 | 4 |
| 1999 | 0 | 6 | 6 |
| 2000 | 2 | 8 | 10 |
| 2001 | 1 | 6 | 7 |
| 2002 | 1 | 10 | 11 |
| 2003 | 1 | 7 | 8 |
| 2004 | 0 | 6 | 6 |
| 2005 | 3 | 12 | 15 |
| 2006 | 1 | 10 | 11 |
| 2007 | 5 | 9 | 14 |
| 2008 | 3 | 7 | 10 |
| 2009 | 2 | 15 | 17 |
| 2010 | 4 | 10 | 14 |
| 2011 | 2 | 9 | 11 |
| 2012 | 2 | 11 | 13 |
| 2013 | 4 | 14 | 18 |
| 2014 | 1 | 12 | 13 |
| 2015 | 1 | 11 | 12 |
| 2016 | 3 | 9 | 12 |
| 2017 | 1 | 9 | 10 |
| 2018 | 0 | 9 | 9 |
| 2019 | 3 | 8 | 11 |
| 2020 | 2 | 7 | 9 |
| 2021 | 0 | 3 | 3 |
| 2022 | 1 | 1 | 2 |
| 2024 | 0 | 2 | 2 |
| 2025 | 0 | 3 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Deletion" by people in Profiles.
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Transcription factor 21 deletion from podocyte precursors as a model for congenital nephrotic syndrome. Am J Physiol Renal Physiol. 2026 06 01; 330(6):F746-F760.
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Clinical Significance of MTAP Deletions and Their Overlap With Concurrent Oncogenic Driver Alterations Including EGFR in NSCLC. J Thorac Oncol. 2026 03; 21(3):103520.
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Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida. ACS Synth Biol. 2025 07 18; 14(7):2739-2752.
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PKCd Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells. Cancer Immunol Res. 2025 04 02; 13(4):547-559.
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MGA deletion leads to Richter's transformation by modulating mitochondrial OXPHOS. Sci Transl Med. 2024 07 31; 16(758):eadg7915.
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Uterine Inflammatory Myofibroblastic Tumors: p16 as a Surrogate for CDKN2A Deletion and Predictor of Aggressive Behavior. Am J Surg Pathol. 2024 Jul 01; 48(7):813-824.
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Ordered and deterministic cancer genome evolution after p53 loss. Nature. 2022 08; 608(7924):795-802.
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PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
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AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. Cereb Cortex. 2021 08 26; 31(10):4808-4824.
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Detection of a mosaic CDKL5 deletion and inversion by optical genome mapping ends an exhaustive diagnostic odyssey. Mol Genet Genomic Med. 2021 07; 9(7):e1665.